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Pretreatment MRI in...
Pretreatment MRI in Primary Rectal Cancer as a Predictor for Oncological Outcomes After Surgery for Local Recurrence
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- Elliot, Anders H. (författare)
- Karolinska Institutet
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- Othman, Barwar N. (författare)
- Karolinska Univ Hosp, Dept Imaging & Physiol, Stockholm, Sweden
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- Suzuki, Chikako (författare)
- Karolinska Institutet
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- Blomqvist, Lennart (författare)
- Karolinska Institutet
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- Martling, Anna (författare)
- Karolinska Institutet
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- Johansson, Hemming (författare)
- Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden
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- Glimelius, Bengt (författare)
- Uppsala universitet,Experimentell och klinisk onkologi
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- Nilsson, Per J. (författare)
- Karolinska Institutet
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- Iversen, Henrik (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2021-05-05
- 2021
- Engelska.
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Ingår i: Anticancer Research. - : Anticancer Research USA Inc.. - 0250-7005 .- 1791-7530. ; 41:5, s. 2459-2465
- Relaterad länk:
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https://ar.iiarjourn...
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https://urn.kb.se/re...
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https://doi.org/10.2...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background/Aim: For patients with locally recurrent rectal cancer (LRRC) extensive surgery is often the only curative option and patient selection is crucial. This study aimed to investigate whether magnetic resonance imaging (MRI) characteristics of the primary tumour can predict oncological outcome after surgery for locally recurrent rectal cancer (LRRC). Patients andMethods: All patients undergoing surgery for LRRC with a curative intent at the Karolinska University Hospital 2003-2013 were included. MRI examinations of the primary tumour were re-evaluated.Results: In total, 54 patients were included. A tumour volume decrease of <70% after preoperative radiotherapy or chemoradiotherapy (C)RT for the primary tumour was correlated with a lower proportion of R0 resection of the LRRC (OR=0.07, 95% CI=0.01-0.84). No association between MRI characteristics of the primary tumour and prognosis after LRRC surgery was found.Conclusion: Long-term outcomes after surgery for LRRC were not significantly associated with MRI characteristics of the index tumour. However, factors associated with increased risk of R1 resection of LRRC were identified.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Rectal cancer
- local recurrence
- MRI
- preoperative treatment
- oncological outcome
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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