onr:"swepub:oai:DiVA.org:uu-4671"
Sökning: onr:"swepub:oai:DiVA.org:uu-4671" > Regulation of Breat...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
- Rieger-Fackeldey, Esther,1960-Uppsala universitet,Institutionen för kvinnors och barns hälsa (författare)
Regulation of Breathing under Different Pulmonary Conditions
- BokEngelska2004
Förlag, utgivningsår, omfång ...
- Uppsala :Acta Universitatis Upsaliensis,2004
- 40 s.
- electronicrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:uu-4671
- ISBN:9155460968
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4671URI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Serie
- Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine,0282-7476 ;1390
Anmärkningar
- The breathing pattern of preterm infants is immature and is associated with a variety of reflexes. In a patient on the ventilator these reflexes interfere with spontaneous breathing. A better understanding of the immature control of breathing could lead to further improvements in ventilatory techniques. This thesis concerns studies of pulmonary stretch receptor (PSR) and phrenic nerve activity as part of the regulation of breathing in an animal model.During assist/control ventilation with three different inspiratory pressure waveforms in animals with healthy lungs, squarewave pressure waveform strongly inhibits spontaneous inspiratory activity.During partial liquid ventilation (PLV) in animals with healthy lungs, all PSRs studied maintained their phasic character, with increased impulse frequency during inspiration. PSR activity was not higher during PLV than during gas ventilation (GV), indicating that there was no extensive stretching of the lung during PLV.During proportional assist ventilation (PAV) the applied airway pressure is servo-controlled proportionally to the ongoing breathing effort, thereby interacting with the activity of PSRs. Peak PSR activity was higher and occurred earlier during PAV than during CPAP. The regulation of breathing is maintained during PAV in surfactant-depleted animals before and early after surfactant instillation, with a higher ventilatory response and a lower breathing effort than during CPAP in both conditions.Both lung mechanics and gas exchange influence the regulation of breathing. Inhibition of inspiratory activity occurred at a lower arterial pH and a higher PaCO2 during PLV than during GV in animals with surfactant-depleted lungs, which might be related to recruitment of a larger number of pulmonary stretch receptors during PLV.In summary, selected aspects of the regulation of breathing were studied in an animal model with different ventilatory techniques under different lung conditions similar to those that can occur in infants.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Pediatrik hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Pediatrics hsv//eng
- Pediatrics
- Control of breathing
- Pulmonary Stretch Receptor
- Phrenic Nerve Activity
- Respiratory Distress Syndrome
- Surfactant
- Partial Liquid Ventilation
- Assisted Ventilation
- Pediatrik
- Paediatric medicine
- Pediatrisk medicin
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Sedin, Gunnar (preses)
- Jonzon, Anders (preses)
- Sindelar, Richard (preses)
- Schulze, Andreas (preses)
- Martin, Richard,MDDivision of Neonatology, Rainbow Babies and Children's Hospital, Cleveland, OH, USA (opponent)
- Uppsala universitetInstitutionen för kvinnors och barns hälsa (creator_code:org_t)
Internetlänk
Hitta via bibliotek
- Regulation of Breathing under Different Pulmonary Conditions (Sök publikationen i LIBRIS)
Till lärosätets databas
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Rieger-Fackeldey ...
- Sedin, Gunnar
- Jonzon, Anders
- Sindelar, Richar ...
- Schulze, Andreas
- Martin, Richard, ...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Pediatrik
- Delar i serien
- Comprehensive Su ...
- Av lärosätet
- Uppsala universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
