Sökning: onr:"swepub:oai:DiVA.org:uu-518472" > Long-Term Outcome o...
Fältnamn | Indikatorer | Metadata |
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001 | oai:DiVA.org:uu-518472 | |
003 | SwePub | |
008 | 231219s2023 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:37667843-09bd-4033-be63-9683beb0ce1b | |
009 | oai:prod.swepub.kib.ki.se:237818181 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5184722 URI |
024 | 7 | a https://doi.org/10.1089/whr.2023.00732 DOI |
024 | 7 | a https://lup.lub.lu.se/record/37667843-09bd-4033-be63-9683beb0ce1b2 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:2378181812 URI |
040 | a (SwePub)uud (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Calissendorff, Janu Karolinska Institutet,Karolinska Institute,Karolinska University Hospital4 aut |
245 | 1 0 | a Long-Term Outcome of Graves' Disease :b A Gender Perspective |
264 | 1 | b Mary Ann Liebert,c 2023 |
338 | a electronic2 rdacarrier | |
520 | a Introduction: In gender-skewed conditions such as Graves' disease (GD), the outcome naturally becomes dominated by the majority. This may lead to gender-biased misunderstandings regarding treatment outcomes. This especially holds true when complications, such as depression, are unevenly distributed. We have, therefore, studied the long-term outcome of GD from a gender perspective.Materials and Methods: A cohort of 1186 patients with GD was included in a follow-up 6-10 years after inclusion. Choice of treatment, the feeling of recovery, long-term treatment, comorbidity, and quality of life were investigated with questionnaires. All results were studied sex-divided.Results: We included 973 women and 213 men. There was no difference between men and women in the choice of treatment. At follow-up, women scored significantly worse in the general questionnaire 36-item Short-Form Health Status (SF-36) domain bodily pain and in the thyroid-specific Thyroid-Related Patient-Reported Outcome (ThyPRO) domains depression, impaired sex life, and cosmetic complaints, all p < 0.05. Women were twice as likely (29.5%) to be treated with levothyroxine after successful treatment with antithyroid drugs (ATD) compared with men (14.9%, p < 0.05).Conclusion: After treatment for GD, women were more affected by depression, impaired sex life, cosmetic issues, and bodily pain despite successful cure of hyperthyroidism. The prevalence of hypothyroidism was also doubled in women. Whether these observed gender differences reflect a worse outcome of GD in women or a natural consequence of a higher prevalence of these symptoms and autoimmunity in the female population is difficult to disentangle. Nevertheless, several years after GD, women reveal more persistent symptoms. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng |
653 | a quality of life | |
653 | a long-term follow-up | |
653 | a Graves disease | |
653 | a Graves disease | |
653 | a long-term follow-up | |
653 | a quality of life | |
700 | 1 | a Cramon, Per Karkovu Rigshospitalet, Copenhagen Univ Hosp, Dept Clin Physiol & Nucl Med, Copenhagen, Denmark.,Copenhagen University Hospital4 aut |
700 | 1 | a Hallengren, Bengtu Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-bha |
700 | 1 | a Khamisi, Selwanu Uppsala University,Uppsala universitet,Endokrinologi och mineralmetabolism,Uppsala Univ Hosp, Dept Endocrinol & Diabet, Uppsala, Sweden.,Uppsala University Hospital4 aut0 (Swepub:uu)selkh262 |
700 | 1 | a Lantz, Mikaelu Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-mla |
700 | 1 | a Planck, Terezau Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-tvo |
700 | 1 | a Sjölin, Gabrielu Örebro Univ Hosp, Fac Med & Hlth, Örebro, Sweden.,Örebro University Hospital4 aut |
700 | 1 | a Wallin, Göranu Karolinska Institute,Örebro University Hospital4 aut |
700 | 1 | a Holmberg, Matsu Karolinska Institutet,Karolinska Institute,Karolinska University Hospital4 aut |
710 | 2 | a Karolinska Instituteb Karolinska University Hospital4 org |
773 | 0 | t Women's Health Reportsd : Mary Ann Liebertg 4:1, s. 487-496q 4:1<487-496x 2688-4844 |
856 | 4 | u https://doi.org/10.1089/whr.2023.0073y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1821234/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u http://dx.doi.org/10.1089/whr.2023.0073x freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-518472 |
856 | 4 8 | u https://doi.org/10.1089/whr.2023.0073 |
856 | 4 8 | u https://lup.lub.lu.se/record/37667843-09bd-4033-be63-9683beb0ce1b |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:237818181 |
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