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  • Fröjd, Victoria,1986Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials (författare)

Importance of Ca(2+) Modifications for Osseointegration of Smooth and Moderately Rough Anodized Titanium Implants - A Removal Torque and Histological Evaluation in Rabbit.

  • Artikel/kapitelEngelska2012

Förlag, utgivningsår, omfång ...

  • 2010-10-26
  • Wiley,2012

Nummerbeteckningar

  • LIBRIS-ID:oai:gup.ub.gu.se/129086
  • https://gup.ub.gu.se/publication/129086URI
  • https://doi.org/10.1111/j.1708-8208.2010.00315.xDOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-15560URI

Kompletterande språkuppgifter

  • Språk:engelska

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  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Background: Incorporation of Ca(2+) into the titania of anodized titanium surfaces has been found to enhance osseointegration. It provides a stable surface when the ions are incorporated into the oxide layer during the anodizing process. The Ca(2+) may suggestively be prominent sites for mineral induction, attract proteins, and catalyze intracellular cascades. Purpose: The aim of the present study was to evaluate the osseointegration of smooth (S(a) < 0.5µm) and moderately rough (S(a) 1.0-2.0µm) commercially pure titanium implants, with and without Ca(2+) , in order to reflect on the importance of surface chemistry in relation to topography. Materials and Methods: Anodized implants with (OxCa) or without Ca(2+) (Ox), blasted implants (Bl), and blasted anodized implants, with (BlOxCa) or without Ca(2+) (BlOx), were inserted in rabbit femur and tibia. The implant surfaces were characterized using interferometry, scanning electron microscopy, and X-ray photoelectron spectroscopy prior to implant installation. Removal torque (RTQ) measurements were executed on all implants after a healing period of 12 weeks. The implants were, thereafter, removed en bloc with surrounding tissues and prepared for histological evaluations. Results: RTQ measurements of tibial implants revealed significantly higher values for BlOxCa implants (90.7 ± 23.3 Ncm) compared to OxCa (64.6 ± 18.2 Ncm) and BlOx implants (69.7 ± 17.5 Ncm) (p = 0.029). Ca(2+) modification of smooth implants placed in the femur did not reveal any differences. Conclusion: Ca(2+) modification of smooth implants resulted in similar interfacial shear strength as moderately rough implants and Ca(2+) modification of moderately rough implants demonstrated the significantly strongest interfacial shear strength when placed in rabbit tibia. This possibly demonstrated surface chemistry compensating for lesser roughness.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Wennerberg, Ann,1955Malmö högskola,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,Odontologiska fakulteten (OD)(Swepub:mau)odanwe (författare)
  • Franke Stenport, Victoria,1970Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology(Swepub:gu)xstevi (författare)
  • Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Clinical implant dentistry and related research: Wiley14:5, s. 737-7451708-82081523-0899

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