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Importance of Ca(2+...
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Fröjd, Victoria,1986Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
(författare)
Importance of Ca(2+) Modifications for Osseointegration of Smooth and Moderately Rough Anodized Titanium Implants - A Removal Torque and Histological Evaluation in Rabbit.
- Artikel/kapitelEngelska2012
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LIBRIS-ID:oai:gup.ub.gu.se/129086
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https://gup.ub.gu.se/publication/129086URI
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https://doi.org/10.1111/j.1708-8208.2010.00315.xDOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-15560URI
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Background: Incorporation of Ca(2+) into the titania of anodized titanium surfaces has been found to enhance osseointegration. It provides a stable surface when the ions are incorporated into the oxide layer during the anodizing process. The Ca(2+) may suggestively be prominent sites for mineral induction, attract proteins, and catalyze intracellular cascades. Purpose: The aim of the present study was to evaluate the osseointegration of smooth (S(a) < 0.5µm) and moderately rough (S(a) 1.0-2.0µm) commercially pure titanium implants, with and without Ca(2+) , in order to reflect on the importance of surface chemistry in relation to topography. Materials and Methods: Anodized implants with (OxCa) or without Ca(2+) (Ox), blasted implants (Bl), and blasted anodized implants, with (BlOxCa) or without Ca(2+) (BlOx), were inserted in rabbit femur and tibia. The implant surfaces were characterized using interferometry, scanning electron microscopy, and X-ray photoelectron spectroscopy prior to implant installation. Removal torque (RTQ) measurements were executed on all implants after a healing period of 12 weeks. The implants were, thereafter, removed en bloc with surrounding tissues and prepared for histological evaluations. Results: RTQ measurements of tibial implants revealed significantly higher values for BlOxCa implants (90.7 ± 23.3 Ncm) compared to OxCa (64.6 ± 18.2 Ncm) and BlOx implants (69.7 ± 17.5 Ncm) (p = 0.029). Ca(2+) modification of smooth implants placed in the femur did not reveal any differences. Conclusion: Ca(2+) modification of smooth implants resulted in similar interfacial shear strength as moderately rough implants and Ca(2+) modification of moderately rough implants demonstrated the significantly strongest interfacial shear strength when placed in rabbit tibia. This possibly demonstrated surface chemistry compensating for lesser roughness.
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Wennerberg, Ann,1955Malmö högskola,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,Odontologiska fakulteten (OD)(Swepub:mau)odanwe
(författare)
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Franke Stenport, Victoria,1970Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology(Swepub:gu)xstevi
(författare)
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Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap
(creator_code:org_t)
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Ingår i:Clinical implant dentistry and related research: Wiley14:5, s. 737-7451708-82081523-0899
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