Pneumoproteins and inflammatory biomarkers in asphalt pavers.

Pneumoproteins, biomarkers of systemic inflammation and endothelial activation were studied across a season in 72 asphalt pavers, 32 asphalt plant operators and 19 asphalt engineers. Smokers had lower concentrations of Clara cell protein (CC-16) and surfactant protein A, but higher concentrations of surfactant protein D, interleukin 6, C-reactive protein, fibrinogen and intercellular adhesion molecule (ICAM)-1 than non-smokers. Smokers reporting wheezing had lower mean CC-16 concentration than smokers not reporting wheezing (5.7 vs 8.6 microg l(-1); p = 0.05). Cholesterol, P-selectin and ICAM-1 were lower in pavers and operators at the end compared with the start of the season. This may be related to increased physical activity during the season.

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Arbetsmedicin och miljömedicin hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Occupational Health and Environmental Health hsv//eng
Adult
Biological Markers
analysis
Cell Adhesion Molecules
analysis
Construction Materials
Cytokines
blood
Endothelium
Vascular
physiology
Enzyme-Linked Immunosorbent Assay
Female
Fibrinogen
Humans
Hydrocarbons
Inflammation
metabolism
Interleukin-6
Linear Models
Lung
chemistry
Male
Middle Aged
Norway
epidemiology
Obesity
complications
epidemiology
Occupational Exposure
analysis
P-Selectin
Proteins
chemistry
Questionnaires
Respiratory Function Tests
Respiratory Tract Diseases
epidemiology
Seasons
Smoking
epidemiology
Spirometry
Young Adult

Ulvestad, Bente (författare)
Andersson, LenaGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine (författare)
Barregård, Lars,1948Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine(Swepub:gu)xbarrl (författare)
Göteborgs universitetInstitutionen för medicin, avdelningen för samhällsmedicin och folkhälsa (creator_code:org_t)

Ingår i:Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals15:6, s. 498-5071366-5804

Av författaren/redakt...: Ellingsen, Dag G; Ulvestad, Bente; Andersson, Lena; Barregård, Lars, ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Hälsovetenskap; och Arbetsmedicin oc ...

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.