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Proteasome inhibiti...
Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells.
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Sloss, Callum M (författare)
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Wang, Fang (författare)
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Liu, Rong (författare)
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Xia, Lijun (författare)
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Houston, Michael (författare)
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- Ljungman, David (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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Palladino, Michael A (författare)
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Cusack, James C (författare)
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(creator_code:org_t)
- 2008
- 2008
- Engelska.
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Ingår i: Clinical cancer research : an official journal of the American Association for Cancer Research. - 1078-0432. ; 14:16, s. 5116-23
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- In the current study, we investigate the activation of antiapoptotic signaling pathways in response to proteasome inhibitor treatment in pancreatic cancer and evaluate the use of concomitant inhibition of these pathways to augment proteasome inhibitor treatment responses.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Adenocarcinoma
- drug therapy
- metabolism
- Animals
- Antibodies
- Monoclonal
- administration & dosage
- Antibodies
- Monoclonal
- Humanized
- Antineoplastic Combined Chemotherapy Protocols
- therapeutic use
- Apoptosis
- drug effects
- physiology
- Blotting
- Western
- Boronic Acids
- administration & dosage
- Cell Line
- Tumor
- Deoxycytidine
- administration & dosage
- analogs & derivatives
- Female
- Humans
- Lactones
- administration & dosage
- Mice
- Mice
- Nude
- Pancreatic Neoplasms
- drug therapy
- metabolism
- Phosphatidylinositol 3-Kinases
- drug effects
- metabolism
- Protease Inhibitors
- therapeutic use
- Proteasome Inhibitors
- Pyrazines
- administration & dosage
- Pyrroles
- administration & dosage
- Quinazolines
- administration & dosage
- Receptor
- Epidermal Growth Factor
- drug effects
- metabolism
- Signal Transduction
- drug effects
- physiology
- Xenograft Model Antitumor Assays
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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