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In vitro platelet f...
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Safai-Kutti, Soodabeh
(författare)
In vitro platelet function in infantile autism.
- Artikel/kapitelEngelska1988
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LIBRIS-ID:oai:gup.ub.gu.se/197866
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https://gup.ub.gu.se/publication/197866URI
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It has previously been demonstrated that patients with infantile autism demonstrate impaired in vivo platelet behaviour. Therefore, in 14 children (13 boys and 1 girl) with infantile autism (aged 2-14, mean 6 years) and 12 healthy control boys (aged 6-15, mean 11 years) we studied in vitro platelet reactivity using ADP- and collagen-induced platelet aggregation. In each child a total of 7 different final concentrations of ADP and 4 different concentrations of collagen were employed. At all concentrations of ADP and collagen used the autistic children consistently exhibited diminished platelet aggregability; the differences, however, did not reach statistical significance. Therefore a wider panel of in vitro tests is apparently required and a larger group of patients be studied to help elucidate the functional/metabolic platelet defect met in infantile autism.
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Denfors, I
(författare)
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Kutti, JackGothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine(Swepub:gu)xkutja
(författare)
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Wadenvik, Hans,1955Gothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine(Swepub:gu)xwadha
(författare)
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Göteborgs universitetMedicinska institutionen
(creator_code:org_t)
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Ingår i:Folia haematologica (Leipzig, Germany : 1928)115:6, s. 897-9010323-4347
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