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Evaluation of catio...
Evaluation of cationic micropeptides derived from the innate immune system as inhibitors of marine biofouling
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- Trepos, R. (författare)
- University of Portsmouth, UK
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- Cervin, Gunnar, 1967 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för biologi och miljövetenskap, Tjärnö marinbiologiska laboratorium,Department of Biological and Environmental Sciences, Tjärnö Marine Biological Laboratory,University of Gothenburg, Sweden
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- Pile, C. (författare)
- University of Portsmouth, UK
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- Pavia, Henrik, 1964 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för biologi och miljövetenskap, Tjärnö marinbiologiska laboratorium,Department of Biological and Environmental Sciences, Tjärnö Marine Biological Laboratory,University of Gothenburg, Sweden
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- Hellio, C. (författare)
- University of Western Brittany, France
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- Svenson, Johan (författare)
- RISE,SP Kemi Material och Ytor,UiT The Arctic University of Norway, Norway
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(creator_code:org_t)
- 2015-06-09
- 2015
- Engelska.
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Ingår i: Biofouling. - : Informa UK Limited. - 0892-7014 .- 1029-2454. ; 31:4, s. 393-403
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- A series of 13 short synthetic amphiphilic cationic micropeptides, derived from the antimicrobial iron-binding innate defence protein lactoferrin, have been evaluated for their capacity to inhibit the marine fouling process. The whole biofouling process was studied and microfouling organisms such as marine bacteria and microalgae were included as well as the macrofouling barnacle Balanus improvisus. In total 19 different marine fouling organisms (18 microfoulers and one macrofouler) were included and both the adhesion and growth of the microfoulers were investigated. It was shown that the majority of the peptides inhibited barnacle cyprid settlement via a reversible nontoxic mechanism, with IC50 values as low as 0.5 mu g ml(-1). Six peptides inhibited adhesion and growth of microorganisms. Two of these were particularly active against the microfoulers with MIC-values ranging between 0.01 and 1 mu g ml(-1), which is comparable with the commercial reference antifoulant SeaNine.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
Nyckelord
- antifouling
- innate defence
- nontoxic
- peptides
- amphiphilic
- SYNTHETIC ANTIMICROBIAL PEPTIDOMIMETICS
- BARNACLE BALANUS-IMPROVISUS
- ANTIFOULING COMPOUNDS
- ANTIBACTERIAL PEPTIDES
- BOVINE LACTOFERRIN
- RELEASE COATINGS
- NATURAL-PRODUCTS
- FOULING-RELEASE
- ANALOGS
- STABILITY
- Biotechnology & Applied Microbiology
- Marine & Freshwater Biology
- XTER SC
- 1993
- BIOFOULING
- V7
- P97
- amphiphilic
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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