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Infective endocardi...
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Alestig, Kjell,1931Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases
(författare)
Infective endocarditis: a diagnostic and therapeutic challenge for the new millennium.
- Artikel/kapitelEngelska2000
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2009-07-08
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Informa UK Limited,2000
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LIBRIS-ID:oai:gup.ub.gu.se/285411
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https://gup.ub.gu.se/publication/285411URI
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https://doi.org/10.1080/003655400750044908DOI
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This review on infective endocarditis (IE) is based on clinical studies carried out in Göteborg since 1984, data obtained from a Swedish national registry of IE since 1995 and existing literature. IE is still a great challenge in medicine, although improved bacteriological and echocardiographical techniques have facilitated diagnosis. In Sweden the incidence of IE is about 6 per 100,000 inhabitants a year. During recent decades IE has changed character. Patients are older, fever is often the only major symptom and a new murmur is less frequent. Streptococci, including viridans species and staphylococci, are still the most common bacteria found. Antibiotic treatment for 4-6 weeks may reduce mortality of IE to 30-50%. For further reduction, heart surgery is necessary in 20-25% of patients in order to remove infected tissues and restore valve function. Rapid diagnosis, careful antibiotic treatment and optimal surgery may reduce mortality associated with treatment to 10%. Antibiotic treatment is still mainly empiric. Penicillin and aminoglycoside for 2 weeks only seem to be effective in uncomplicated IE caused by alpha-streptococci. Otherwise, 4 weeks of treatment is needed, but aminoglycoside treatment may be reduced to 1 week in general and 2 weeks for enterococcal infections.
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Hogevik, HarrietGothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases
(författare)
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Olaison, Lars,1949Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för infektionssjukdomar,Institute of Internal Medicine, Dept of Infectious Diseases(Swepub:gu)xolala
(författare)
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Göteborgs universitetInstitutionen för invärtesmedicin, Avdelningen för infektionssjukdomar
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Scandinavian journal of infectious diseases: Informa UK Limited32:4, s. 343-560036-55481651-1980
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