Sökning: onr:"swepub:oai:gup.ub.gu.se/45625" >
Coronary heart dise...
Coronary heart disease mortality after 5 years of adjuvant tamoxifen therapy: results from a randomized trial
-
- Nordenskjöld, Bo, 1940- (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Onkologi,Onkologiska kliniken US
-
- Rosell, Johan, 1966- (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Onkologi,Onkologiska kliniken US
-
- Rutqvist, L. E. (författare)
- Department of Oncology, Södersjukhuset Hospital, Stockholm, Sweden
-
visa fler...
-
- Malmström, Per (författare)
- Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Oncology, Lund University Hospital, Lund, Sweden
-
- Bergh, J. (författare)
- Karolinska Institutet,Department of Oncology, Karolinska Hospital, Stockholm, Sweden
-
- Bengtsson, Nils-Olof (författare)
- Umeå universitet,Onkologi,Department of Oncology, Umeå University Hospital, Umeå, Sweden
-
- Hatschek, T. (författare)
- Karolinska Institutet,Department of Oncology, Karolinska Hospital, Stockholm, Sweden
-
- Wallgren, Arne, 1940 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för onkologi,Institute of Selected Clinical Sciences, Department of Oncology,Department of Oncology, Sahlgrenska University Hospital, Göteborg, Sweden
-
- Carstensen, John, 1953- (författare)
- Linköpings universitet,Filosofiska fakulteten,Tema hälsa och samhälle
-
visa färre...
-
(creator_code:org_t)
- Oxford University Press (OUP), 2005
- 2005
- Engelska.
-
Ingår i: J Natl Cancer Inst. - : Oxford University Press (OUP). - 1460-2105 .- 0027-8874. ; 97:21, s. 1609-10
- Relaterad länk:
-
http://dx.doi.org/10... (free)
-
visa fler...
-
https://academic.oup...
-
https://gup.ub.gu.se...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- From January 1, 1983, through December 31, 1992, a total of 4610 patients entered a randomized trial that compared mortality among patients receiving 2 years of adjuvant tamoxifen therapy with that in patients receiving 5 years of adjuvant tamoxifen therapy, 4175 of whom were recurrence free after 2 years of tamoxifen therapy. Among the 2046 patients randomly assigned to the 5-year group all-cause mortality, breast cancer-specific mortality, and the incidence of contralateral breast cancer were reduced, compared with those among 2129 patients randomized in the 2-year group, but the incidence of endometrial cancer was increased. In addition, mortality from coronary heart disease was statistically significantly reduced in the 5-year group, compared with that in the 2-year group (hazard ratio = 0.67, 95% confidence interval = 0.47 to 0.94; P = .022 [two-sided Wald test]). Ten years after surgery, 2.1% of the patients in the 5-year group and 3.5% of those in the 2-year group had died from coronary heart disease. No statistically significant increases in mortality from other heart diseases, cerebrovascular diseases, or other vascular diseases were observed.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Aged
- Antineoplastic Agents
- Hormonal/*administration & dosage
- Breast Neoplasms/*drug therapy/prevention & control
- Chemotherapy
- Adjuvant
- Coronary Disease/*mortality
- Drug Administration Schedule
- Estrogen Receptor Modulators/*administration & dosage
- Female
- Humans
- Incidence
- Middle Aged
- Mortality/trends
- Odds Ratio
- Postmenopause
- Proportional Hazards Models
- Registries
- Sweden/epidemiology
- Tamoxifen/*administration & dosage
- Time Factors
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Nordenskjöld, Bo ...
-
Rosell, Johan, 1 ...
-
Rutqvist, L. E.
-
Malmström, Per
-
Bergh, J.
-
Bengtsson, Nils- ...
-
visa fler...
-
Hatschek, T.
-
Wallgren, Arne, ...
-
Carstensen, John ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Cancer och onkol ...
- Artiklar i publikationen
-
J Natl Cancer In ...
- Av lärosätet
-
Göteborgs universitet
-
Lunds universitet
-
Umeå universitet
-
Karolinska Institutet
-
Linköpings universitet