Adiponectin, obesity and atherosclerosis.

• The circulating protein adiponectin has been the subject of immense interest ever since it was first discovered in the mid-1990s. The protein is uniquely produced and secreted by mature adipocytes and is believed to have important anti-inflammatory and anti-diabetic effects; low levels have been shown to be predictive of future type 2 diabetes and cardiovascular disease. This review discusses adiponectin in relation to obesity, inflammation, insulin resistance and atherosclerosis.

Nyckelord

Adipocytes

metabolism

Adiponectin

physiology

Animals

Atherosclerosis

metabolism

Cytokines

metabolism

Humans

Insulin Resistance

immunology

Obesity

metabolism

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