Acute megakaryoblastic leukaemia in a patient with systemic lupus erythematosus

• We describe here a 72-year-old female patient with an acute megakaryoblastic leukaemia (M7 by FAB Classification) and systemic lupus erythematosus (SLE). The patient had not been pretreated with immunosuppressive therapy, which is potentially leukaemogenic. The karyotype displayed multiple, structural and numerical anomalies, suggesting a possible de novo rather than a secondary nature of leukaemia.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Hematologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Hematology (hsv//eng)

Nyckelord

Aged

Bone Marrow

Chromosome Aberrations

Chromosome Disorders

Fatal Outcome

Female

Humans

Karyotyping

Leukemia, Megakaryoblastic, Acute

Lupus Erythematosus, Systemic

Megakaryocytes

Publikations- och innehållstyp

art (ämneskategori)

ref (ämneskategori)