Sökning: onr:"swepub:oai:lup.lub.lu.se:37f98723-a4aa-4977-b3e1-cffb1c3e2ef6" >
The relationship between the metabolic syndrome and arterial wall thickness : A mosaic still to be interpreted
-
- Scuteri, Angelo (författare)
- University of Rome Tor Vergata
-
- Franco, Oscar H. (författare)
- Erasmus University Medical Center
-
- Völzke, Henry (författare)
- University of Greifswald
-
visa fler...
-
- Shin, Min Ho (författare)
- Chonnam National University
-
- Kweon, Sun Seog (författare)
- Chonnam National University
-
- Rietzschel, Ernst (författare)
- Ghent University Hospital,Ghent University
-
- Ryliškytė, Ligita (författare)
- Vilnius University Hospital
-
- Strazhesko, Irina (författare)
- Federal State Institution National Research Center for Preventive Medicine, Russia
-
- Chen, Chen Huan (författare)
- National Yang-Ming University Taiwan
-
- Lakatta, Edward G. (författare)
- National Institute on Aging, United States
-
- Nilsson, Peter M. (författare)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
-
visa färre...
-
(creator_code:org_t)
- Elsevier BV, 2016
- Engelska 6 s.
-
Ingår i: Atherosclerosis. - : Elsevier BV. - 0021-9150. ; 255, s. 11-16
- Relaterad länk:
-
http://dx.doi.org/10...
-
visa fler...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background and aims We aimed to identify clusters of metabolic syndrome (MetS) components, risky for extremely high intima-media thickness. Methods We studied 41,513 volunteers (men and women) from eleven cohorts worldwide, participating in the MARE (Metabolic syndrome and Artery REsearch) Consortium. Results Specific clusters of MetS components - high triglycerides-high blood pressure-abdominal obesity (TBW), low HDL cholesterol-high blood pressure-abdominal obesity (HBW), high glucose-high blood pressure-abdominal obesity (GBW) - were accompanied by a 50–90% significantly greater likelihood of presenting extremely high intima-media thickness (via ultrasound of carotid artery, CCA IMT), after controlling for age, sex, smoking, non-HDL cholesterol, and presence of diabetes mellitus. This likelihood is comparable to the effect of being 7–8 years older or of being a cigarette smoker or of having non-HDL cholesterol 50 mg/dl higher. Conclusions The consistent association of specific clusters of MetS components with extremely thick (older) large artery cross-culturally suggests that identification of those clusters in clinical practice will facilitate a personalized health care and a better – i.e. more healthy and cost-effective - prevention of major cardiovascular (CV) events.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Arterial ageing
- Arteries
- Carotid intima-media thickness
- Metabolic syndrome
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
- Av författaren/redakt...
-
Scuteri, Angelo
-
Franco, Oscar H.
-
Völzke, Henry
-
Shin, Min Ho
-
Kweon, Sun Seog
-
Rietzschel, Erns ...
-
visa fler...
-
Ryliškytė, Ligit ...
-
Strazhesko, Irin ...
-
Chen, Chen Huan
-
Lakatta, Edward ...
-
Nilsson, Peter M ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Kardiologi
- Artiklar i publikationen
-
Atherosclerosis
- Av lärosätet
-
Lunds universitet