Sökning: onr:"swepub:oai:lup.lub.lu.se:38732062-a382-403f-8b68-712db346d7bf" > Fiber intake modula...
Fältnamn | Indikatorer | Metadata |
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000 | 08372naa a2200985 4500 | |
001 | oai:lup.lub.lu.se:38732062-a382-403f-8b68-712db346d7bf | |
003 | SwePub | |
008 | 161205s2017 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-129409 | |
009 | oai:prod.swepub.kib.ki.se:134926491 | |
024 | 7 | a https://lup.lub.lu.se/record/38732062-a382-403f-8b68-712db346d7bf2 URI |
024 | 7 | a https://doi.org/10.1002/ijc.304152 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1294092 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1349264912 URI |
040 | a (SwePub)lud (SwePub)umud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Romieu, Isabelleu International Agency for Research on Cancer, World Health Organization4 aut |
245 | 1 0 | a Fiber intake modulates the association of alcohol intake with breast cancer |
264 | c 2016-11-21 | |
264 | 1 | b Wiley,c 2017 |
520 | a Alcohol intake has been related to an increased risk of breast cancer (BC) while dietary fiber intake has been inversely associated to BC risk. A beneficial effect of fibers on ethanol carcinogenesis through their impact on estrogen levels is still controversial. We investigated the role of dietary fiber as a modifying factor of the association of alcohol and BC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC). This study included 334,850 women aged 35–70 years at baseline enrolled in the ten countries of the EPIC study and followed up for 11.0 years on average. Information on fiber and alcohol intake at baseline and average lifetime alcohol intake were calculated from country-specific dietary and lifestyle questionnaires. Hazard ratios (HR) of developing invasive BC according to different levels of alcohol and fiber intake were computed. During 3,670,439 person-years, 11,576 incident BC cases were diagnosed. For subjects with low intake of fiber (<18.5 g/day), the risk of BC per 10 g/day of alcohol intake was 1.06 (1.03–1.08) while among subjects with high intake of fiber (>24.2 g/day) the risk of BC was 1.02 (0.99–1.05) (test for interaction p = 0.011). This modulating effect was stronger for fiber from vegetables. Our results suggest that fiber intake may modulate the positive association of alcohol intake and BC. Alcohol is well known to increase the risk for BC, while a fiber-rich diet has the opposite effect. Here the authors find a significant interaction between both lifestyle factors indicating that high fiber intake can ease the adverse effects associated with alcohol consumption. Consequently, women with high alcohol intake and low fiber intake (<18.5 g/day) had the highest risk for BC. Specific benefits were associated with fibers from vegetable, warranting further investigations into specific fiber sources and their mechanistic interactions with alcohol-induced BC risk. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a alcohol | |
653 | a breast cancer | |
653 | a epidemiology | |
653 | a nutrition | |
653 | a alcohol | |
700 | 1 | a Ferrari, Pietrou International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Chajès, Veroniqueu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a de Batlle, Jordiu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Biessy, Carineu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Scoccianti, Chiarau International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Dossus, Laureu Institut Gustave Roussy4 aut |
700 | 1 | a Christine Boutron, Marieu Institut Gustave Roussy4 aut |
700 | 1 | a Bastide, Nadiau Institut Gustave Roussy4 aut |
700 | 1 | a Overvad, Kimu Aarhus University4 aut |
700 | 1 | a Olsen, Anjau Danish Cancer Society4 aut |
700 | 1 | a Tjønneland, Anneu Danish Cancer Society4 aut |
700 | 1 | a Kaaks, Rudolfu German Cancer Research Centre4 aut |
700 | 1 | a Boeing, Heineru German Institute of Human Nutrition4 aut |
700 | 1 | a Trichopoulou, Antoniau National and Kapodistrian University of Athens4 aut |
700 | 1 | a Lagiou, Pagonau Academy of Athens4 aut |
700 | 1 | a Trichopoulos, Dimitriosu Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Palli, Domenicou Cancer Research and Prevention Institute (ISPO)4 aut |
700 | 1 | a Sieri, Sabinau Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Tumino, Rosariou Civic and M.P Arezzo Hospital4 aut |
700 | 1 | a Vineis, Paolou Human Genetics Foundation (HuGeF)4 aut |
700 | 1 | a Panico, Salvatoreu University of Naples Federico II4 aut |
700 | 1 | a Bueno-de-Mesquita, H. Basu University of Malaya4 aut |
700 | 1 | a Gils, Carla H.u University Medical Center Utrecht4 aut |
700 | 1 | a Peeters, Petra H.u Imperial College London4 aut |
700 | 1 | a Lund, Eilivu UiT The Arctic University of Norway, Tromsø4 aut |
700 | 1 | a Skeie, Guriu UiT The Arctic University of Norway, Tromsø4 aut |
700 | 1 | a Weiderpass, Elisabeteu Karolinska Institutet,Karolinska Institute4 aut |
700 | 1 | a Ramón Quirós, J.u Public Health Directorate4 aut |
700 | 1 | a Chirlaque, María Doloresu Murcia Regional Health Authority4 aut |
700 | 1 | a Ardanaz, Evau Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Health Research Institute of Navarra (IDISNA)4 aut0 (Swepub:lu)extLU-05 |
700 | 1 | a Sánchez, María Joséu Andalusian School Of Public Health (EASP)4 aut |
700 | 1 | a Duell, Eric J.u Catalan Institute of Oncology4 aut |
700 | 1 | a Amiano Etxezarreta, Pilaru CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Borgquist, Signeu Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Bröstcancer-genetik,Institutionen för kliniska vetenskaper, Lund,Bröstcancer - prevention & intervention,Forskargrupper vid Lunds universitet,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Breastcancer-genetics,Department of Clinical Sciences, Lund,Breast cancer prevention & intervention,Lund University Research Groups4 aut0 (Swepub:lu)ront-sbo |
700 | 1 | a Hallmans, Göranu Umeå universitet,Umeå University,Näringsforskning4 aut0 (Swepub:umu)goha0001 |
700 | 1 | a Johansson, Ingegerdu Umeå universitet,Umeå University,Institutionen för odontologi4 aut0 (Swepub:umu)injo0003 |
700 | 1 | a Maria Nilsson, Lenau Umeå universitet,Umeå University,Näringsforskning4 aut0 (Swepub:umu)leni0002 |
700 | 1 | a Khaw, Kay Teeu University of Cambridge4 aut |
700 | 1 | a Wareham, Nicku University of Cambridge4 aut |
700 | 1 | a Key, Timothy J.u University of Oxford4 aut |
700 | 1 | a Travis, Ruth C.u University of Oxford4 aut |
700 | 1 | a Murphy, Neilu Imperial College London4 aut |
700 | 1 | a Wark, Petra A.u Imperial College London4 aut |
700 | 1 | a Riboli, Eliou Imperial College London4 aut |
710 | 2 | a International Agency for Research on Cancer, World Health Organizationb Institut Gustave Roussy4 org |
773 | 0 | t International Journal of Cancerd : Wileyg 140:2, s. 316-321q 140:2<316-321x 0020-7136x 1097-0215 |
856 | 4 | u http://dx.doi.org/10.1002/ijc.30415y FULLTEXT |
856 | 4 | u https://munin.uit.no/bitstream/10037/13295/3/article.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/38732062-a382-403f-8b68-712db346d7bf |
856 | 4 8 | u https://doi.org/10.1002/ijc.30415 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-129409 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:134926491 |
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