SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:lup.lub.lu.se:706c9252-ea0b-4c41-ad64-5afcd277c154"
 

Sökning: onr:"swepub:oai:lup.lub.lu.se:706c9252-ea0b-4c41-ad64-5afcd277c154" > Quantitative versus...

  • Doria, Andrea S. (författare)

Quantitative versus semiquantitative MR imaging of cartilage in blood-induced arthritic ankles: preliminary findings

  • Artikel/kapitelEngelska2014

Förlag, utgivningsår, omfång ...

  • 2014-02-13
  • Springer Science and Business Media LLC,2014

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:706c9252-ea0b-4c41-ad64-5afcd277c154
  • https://lup.lub.lu.se/record/4488291URI
  • https://doi.org/10.1007/s00247-013-2872-1DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Recent advances in hemophilia prophylaxis have raised the need for accurate noninvasive methods for assessment of early cartilage damage in maturing joints to guide initiation of prophylaxis. Such methods can either be semiquantitative or quantitative. Whereas semiquantitative scores are less time-consuming to be performed than quantitative methods, they are prone to subjective interpretation. To test the feasibility of a manual segmentation and a quantitative methodology for cross-sectional evaluation of articular cartilage status in growing ankles of children with blood-induced arthritis, as compared with a semiquantitative scoring system and clinical-radiographic constructs. Twelve boys, 11 with hemophilia (A, n = 9; B, n = 2) and 1 with von Willebrand disease (median age: 13; range: 6-17), underwent physical examination and MRI at 1.5 T. Two radiologists semiquantitatively scored the MRIs for cartilage pathology (surface erosions, cartilage loss) with blinding to clinical information. An experienced operator applied a validated quantitative 3-D MRI method to determine the percentage area of denuded bone (dAB) and the cartilage thickness (ThCtAB) in the joints' MRIs. Quantitative and semiquantitative MRI methods and clinical-radiographic constructs (Hemophilia Joint Health Score [HJHS], Pettersson radiograph scores) were compared. Moderate correlations were noted between erosions and dAB (r = 0.62, P = 0.03) in the talus but not in the distal tibia (P > 0.05). Whereas substantial to high correlations (r range: 0.70-0.94, P < 0.05) were observed between erosions, cartilage loss, HJHS and Pettersson scores both at the distal tibia and talus levels, moderate/borderline substantial (r range: 0.55-0.61, P < 0.05) correlations were noted between dAB/ThCtAB and clinical-radiographic constructs. Whereas the semiquantitative method of assessing cartilage status is closely associated with clinical-radiographic scores in cross-sectional studies of blood-induced arthropathy, quantitative measures provide independent information and are therefore less applicable for that research design.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Zhang, Ningning (författare)
  • Lundin, BjörnLund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)drad-blu (författare)
  • Hilliard, Pamela (författare)
  • Man, Carina (författare)
  • Weiss, Ruth (författare)
  • Detzler, Gary (författare)
  • Blanchette, Victor (författare)
  • Moineddin, Rahim (författare)
  • Eckstein, Felix (författare)
  • Sussman, Marshall S. (författare)
  • Diagnostisk radiologi, LundSektion V (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Pediatric Radiology: Springer Science and Business Media LLC44:5, s. 576-5861432-19980301-0449

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy