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Sökning: onr:"swepub:oai:lup.lub.lu.se:8ef9c5b4-41e5-4b12-a3fe-044816e0d515" > Platelet function t...

  • Szanto, TimeaCoagulation Disorders Unit, Department of Hematology, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland; Research Program in Systems Oncology, Helsinki University, Helsinki, Finland,Helsinki University Central Hospital,Helsinki Univ Hosp, Finland; Univ Helsinki, Finland (författare)

Platelet function testing : Current practice among clinical centres in Northern Europe

  • Artikel/kapitelEngelska2022

Förlag, utgivningsår, omfång ...

  • 2022-05-05
  • Wiley,2022

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:8ef9c5b4-41e5-4b12-a3fe-044816e0d515
  • https://lup.lub.lu.se/record/8ef9c5b4-41e5-4b12-a3fe-044816e0d515URI
  • https://doi.org/10.1111/hae.14578DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-98863URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-185275URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:149466910URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Funding agency:Helsinki University Hospital TYH2020318
  • Funding Agencies|Helsinki University Hospital [TYH2020318]
  • Introduction: Platelet function tests are used to screen and diagnose patients with possible inherited platelet function defects (IPFD). Some acquired platelet dysfunction may be caused by certain drugs or comorbidities, which need to be excluded before testing. Aims: To identify current practice among centres performing platelet function tests in Northern Europe. Methods: A total of 14 clinical centres from Sweden (six), Finland (two), Denmark (two), Norway (one), Estonia (two) and Iceland (one) completed the survey questionnaire, the population capture area of about 29.5 million. Results: Six of the 14 (42.8%) centres providing platelet function assessment represent comprehensive treatment centres (EUHANET status). A Bleeding score (BS) or ISTH bleeding assessment tool (ISTH BAT score) is evaluated in 11/14 (78.6%) centres and family history in all. Five/14 centres (35.7%) use structured preanalytical patient instructions, and 10/14 (71.4%) recorded questionnaire on the preassessment of avoidance of any drugs or natural products affecting platelet functions. Preliminary investigations of screening tests of coagulation are performed in 10/14 (71.4%), while in 4/14 (28.6%), the diagnostic work-up of IPFD and von Willebrand disease (VWD) is performed simultaneously. The work-up of IPFD includes peripheral blood smear in 10/14 (71.4%), platelet aggregometry in all, flow cytometry in 10/14 (71.4%) and Platelet Function Analysis (PFA) in 3/11 (28.6%). Molecular genetic diagnosis is available in 7/14 (50%) centres. Conclusions: The considerable variability in the current practice illustrates the need for harmonization between the Northern European centres according to the international registers (i.e. EUHASS) and IPFD guidelines (ISTH, EHA).

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Zetterberg, EvaLund University,Lunds universitet,Klinisk koagulationsmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Coagulation, Malmö,Lund University Research Groups,Department of Translational Medicine & Centre for Thrombosis and Haemostasis, Lund University, Malmö, Sweden,Lund Univ, Sweden; Lund Univ, Sweden(Swepub:lu)med-ezt (författare)
  • Ramström, Sofia,1973-Linköpings universitet,Örebro universitet,Örebro University,Linköping University,Institutionen för medicinska vetenskaper,Department of Clinical Chemistry and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, Klinisk kemi,Orebro Univ, Sweden(Swepub:liu)sofra86 (författare)
  • Leinøe, Eva B.Department of Haematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark,Copenhagen Univ Hosp, Denmark (författare)
  • Holme, Pål A.Department of Haematology, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway,Univ Oslo, Norway; Univ Oslo, Norway (författare)
  • Antovic, Jovan P.Karolinska Institutet (författare)
  • Holmström, MargaretaLinköpings universitet,Linköping University,Department of Health and Department of Acute Internal Medicine and Geriatrics, Medicine and Caring Sciences Linköping University, Linköping, Sweden,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Medicinska och geriatriska akutkliniken(Swepub:liu)marho73 (författare)
  • Onundarson, Pall T.Faculty of Medicine, University of Iceland, Reykjavik, Iceland,Univ Iceland, Iceland (författare)
  • Pikta, MarikaLaboratory, North Estonia Medical Centre, Tallinn, Estonia,North Estonia Med Ctr, Estonia (författare)
  • Vaide, InesDepartment of Hemato-Oncology, University of Tartu, Institute of Clinical Medicine, Tartu, Estonia,Univ Tartu, Estonia (författare)
  • Olsson, AnnaThe County of Västra Götaland,Region Västra Götaland, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Sweden(Swepub:lu)an5851ol (författare)
  • Magnusson, MariaKarolinska Institutet (författare)
  • Kärkkäinen, SatuHemostasis and Platelet Laboratory, Fimlab Laboratoriot, Tampere, Finland,Fimlab Lab, Finland (författare)
  • Bitar, ManarDepartment of Laboratory Medicine, Clinical Chemistry, Faculty of Medicine and Health, Örebro University Hospital, Örebro, Sweden,Orebro Univ Hosp, Sweden (författare)
  • Poulsen, Lone HvitfeldtCentre for Haemophilia and Thrombosis, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark (författare)
  • Lassila, RiittaHelsinki University Central Hospital,Coagulation Disorders Unit, Department of Hematology, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland; Research Program in Systems Oncology, Helsinki University, Helsinki, Finland,Helsinki Univ Hosp, Finland; Univ Helsinki, Finland (författare)
  • Coagulation Disorders Unit, Department of Hematology, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland; Research Program in Systems Oncology, Helsinki University, Helsinki, FinlandHelsinki University Central Hospital (creator_code:org_t)
  • the Nordic Haemophilia Council

Sammanhörande titlar

  • Ingår i:Haemophilia: Wiley28:4, s. 642-6481351-82161365-2516

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