onr:"swepub:oai:lup.lub.lu.se:953bdd83-d330-4c32-836a-62f15728f82c"
Sökning: onr:"swepub:oai:lup.lub.lu.se:953bdd83-d330-4c32-836a-62f15728f82c" > Contribution of Est...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
- Aigner, AnnetteUniversity Medical Center Hamburg-Eppendorf (författare)
Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
- 2017
- 8 s.
Nummerbeteckningar
- LIBRIS-ID:oai:lup.lub.lu.se:953bdd83-d330-4c32-836a-62f15728f82c
- https://lup.lub.lu.se/record/953bdd83-d330-4c32-836a-62f15728f82cURI
- https://doi.org/10.1161/STROKEAHA.117.016599DOI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- Background and Purpose - As stroke in young adults is assumed to have different etiologies and risk factors than in older populations, the aim of this study was to examine the contribution of established potentially modifiable cardiovascular risk factors to the burden of stroke in young adults. Methods - A German nationwide case-control study based on patients enrolled in the SIFAP1 study (Stroke In Young Fabry Patients) 2007 to 2010 and controls from the population-based GEDA study (German Health Update) 2009 to 2010 was performed. Cases were 2125 consecutive patients aged 18 to 55 years with acute first-ever stroke from 26 clinical stroke centers; controls (age- and sex-matched, n=8500, without previous stroke) were from a nationwide community sample. Adjusted population-attributable risks of 8 risk factors (hypertension, hyperlipidemia, diabetes mellitus, coronary heart disease, smoking, heavy episodic alcohol consumption, low physical activity, and obesity) and their combinations for all stroke, ischemic stroke, and primary intracerebral hemorrhage were calculated. Results - Low physical activity and hypertension were the most important risk factors, accounting for 59.7% (95% confidence interval, 56.3-63.2) and 27.1% (95% confidence interval, 23.6-30.6) of all strokes, respectively. All 8 risk factors combined explained 78.9% (95% confidence interval, 76.3-81.4) of all strokes. Population-attributable risks of all risk factors were similar for all ischemic stroke subtypes. Population-attributable risks of most risk factors were higher in older age groups and in men. Conclusions - Modifiable risk factors previously established in older populations also account for a large part of stroke in younger adults, with 4 risk factors explaining almost 80% of stroke risk.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
- case-control study
- population-attributable risk
- risk factors
- stroke
- young adults
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Grittner, UlrikeCharité - University Medicine Berlin (författare)
- Rolfs, ArndtUniversity of Rostock (författare)
- Norrving, BoLund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk strokeforskning,Forskargrupper vid Lunds universitet,Stroke policy och kvalitetsregisterforskning,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Stroke Research Group,Lund University Research Groups,Stroke policy and quality register research(Swepub:lu)neur-bno (författare)
- Siegerink, BobRobert Koch Institut (författare)
- Busch, Markus A.Robert Koch Institut (författare)
- University Medical Center Hamburg-EppendorfCharité - University Medicine Berlin (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Stroke48:7, s. 1744-17510039-2499
Internetlänk
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Aigner, Annette
- Grittner, Ulrike
- Rolfs, Arndt
- Norrving, Bo
- Siegerink, Bob
- Busch, Markus A.
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Neurologi
- Artiklar i publikationen
- Stroke
- Av lärosätet
- Lunds universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
