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Progression of reti...
Progression of retinopathy in insulin-treated type 2 diabetic patients.
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- Henricsson, Marianne (författare)
- Lund University,Lunds universitet,Oftalmologi (Malmö),Forskargrupper vid Lunds universitet,Ophthalmology (Malmö),Lund University Research Groups
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- Berntorp, Kerstin (författare)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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- Fernlund, Per (författare)
- Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups
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- Sundkvist, Göran (författare)
- Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine
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(creator_code:org_t)
- American Diabetes Association, 2002
- 2002
- Engelska.
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Ingår i: Diabetes Care. - : American Diabetes Association. - 1935-5548 .- 0149-5992. ; 25:2, s. 381-385
- Relaterad länk:
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http://www.ncbi.nlm.... (free)
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visa fler...
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http://dx.doi.org/10... (free)
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http://care.diabetes...
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https://lup.lub.lu.s...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- OBJECTIVE—To study the progression of retinopathy 3 years after initiation of insulin therapy. RESEARCH DESIGN AND METHODS—In a prospective, observational case-control study, 42 type 2 diabetic patients were examined at baseline and 1, 3, 6, 12, 24, and 36 months after change to insulin therapy. Retinopathy was graded based on fundus photographs using the Wisconsin scale; HbA1c and IGF-1 were measured. RESULTS—During the observation period of 3 years, 26 patients progressed in the retinopathy scale; 11 patients progressed at least three levels. After 3 years of insulin therapy, HbA1c and IGF-1 were significantly lower than at baseline. Progression of retinopathy greater than or equal to three levels was related to high IGF-1 levels. CONCLUSIONS—A relationship was found between high IGF-1 levels at 3 years and progression of retinopathy in type 2 diabetic patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Nyckelord
- Treatment Outcome
- Non-U.S. Gov't
- Support
- Prospective Studies
- Middle Age
- Non-Insulin-Dependent: physiopathology
- Diabetic Retinopathy: physiopathology
- Disease Progression
- Logistic Models
- Insulin: administration & dosage
- Hypoglycemic Agents: administration & dosage
- Human
- Follow-Up Studies
- Male
- Female
- Non-Insulin-Dependent: drug therapy
- Diabetes Mellitus
- Non-Insulin-Dependent: complications
- Aged
- Case-Control Studies
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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