Sökning: onr:"swepub:oai:prod.swepub.kib.ki.se:141376635" >
Independent Predict...
Independent Predictors of Cardiac Mortality and Hospitalization for Heart Failure in a Multi-Ethnic Asian ST-segment Elevation Myocardial Infarction Population Treated by Primary Percutaneous Coronary Intervention
-
Bulluck, H (författare)
-
Zheng, HL (författare)
-
Chan, MY (författare)
-
visa fler...
-
Foin, N (författare)
-
Foo, DC (författare)
-
Lee, CW (författare)
-
Lim, ST (författare)
-
- Sahlen, A (författare)
- Karolinska Institutet
-
Tan, HC (författare)
-
Tan, JW (författare)
-
Tong, KL (författare)
-
Wong, AS (författare)
-
Wong, PE (författare)
-
Yeo, KK (författare)
-
Foo, LL (författare)
-
Chua, TS (författare)
-
Koh, TH (författare)
-
Hausenloy, DJ (författare)
-
visa färre...
-
(creator_code:org_t)
- 2019-07-11
- 2019
- Engelska.
-
Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 9:1, s. 10072-
- Relaterad länk:
-
https://www.nature.c...
-
visa fler...
-
http://kipublication...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- We aimed to identify independent predictors of cardiac mortality and hospitalization for heart failure (HHF) from a real-world, multi-ethnic Asian registry [the Singapore Myocardial Infarction Registry] of ST-segment elevation myocardial infarction (STEMI) patients treated by primary percutaneous coronary intervention. 11,546 eligible STEMI patients between 2008 and 2015 were identified. In-hospital, 30-day and 1-year cardiac mortality and 1-year HHF rates were 6.4%, 6.8%, 8.3% and 5.2%, respectively. From the derivation cohort (70% of patients), age, Killip class and cardiac arrest, creatinine, hemoglobin and troponin on admission and left ventricular ejection fraction (LVEF) during hospitalization were predictors of in-hospital, 30-day and 1-year cardiac mortality. Previous ischemic heart disease (IHD) was a predictor of in-hospital and 30-day cardiac mortality only, whereas diabetes was a predictor of 1-year cardiac mortality only. Age, previous IHD and diabetes, Killip class, creatinine, hemoglobin and troponin on admission, symptom-to-balloon-time and LVEF were predictors of 1-year HHF. The c-statistics were 0.921, 0.901, 0.881, 0.869, respectively. Applying these models to the validation cohort (30% of patients) showed good fit and discrimination (c-statistic 0.922, 0.913, 0.903 and 0.855 respectively; misclassification rate 14.0%, 14.7%, 16.2% and 24.0% respectively). These predictors could be incorporated into specific risk scores to stratify reperfused STEMI patients by their risk level for targeted intervention.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Bulluck, H
-
Zheng, HL
-
Chan, MY
-
Foin, N
-
Foo, DC
-
Lee, CW
-
visa fler...
-
Lim, ST
-
Sahlen, A
-
Tan, HC
-
Tan, JW
-
Tong, KL
-
Wong, AS
-
Wong, PE
-
Yeo, KK
-
Foo, LL
-
Chua, TS
-
Koh, TH
-
Hausenloy, DJ
-
visa färre...
- Artiklar i publikationen
-
Scientific repor ...
- Av lärosätet
-
Karolinska Institutet