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Healthy lifestyle c...
Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort
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- Matta, Komodo (författare)
- International Agency for Research on Cancer, World Health Organization
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- Viallon, Vivian (författare)
- International Agency for Research on Cancer, World Health Organization
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- Botteri, Edoardo (författare)
- Cancer Registry of Norway, Institute of Population-Based Cancer Research
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- Peveri, Giulia (författare)
- Karolinska Institute,University of Milan
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- Dahm, Christina (författare)
- Aarhus University
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- Nannsen, Anne Østergaard (författare)
- Aarhus University
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- Olsen, Anja (författare)
- Aarhus University,Danish Cancer Society
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- Tjønneland, Anne (författare)
- Danish Cancer Society,University of Copenhagen
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- Elbaz, Alexis (författare)
- Institut Gustave Roussy
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- Artaud, Fanny (författare)
- Institut Gustave Roussy
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- Marques, Chloé (författare)
- Institut Gustave Roussy
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- Kaaks, Rudolf (författare)
- German Cancer Research Centre
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- Katzke, Verena (författare)
- German Cancer Research Centre
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- Schulze, Matthias B. (författare)
- German Institute of Human Nutrition,University of Potsdam
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- Llanaj, Erand (författare)
- German Center for Diabetes Research,German Institute of Human Nutrition
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- Masala, Giovanna (författare)
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO)
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- Pala, Valeria (författare)
- Istituto Nazionale dei Tumori
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- Panico, Salvatore (författare)
- University of Naples Federico II
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- Tumino, Rosario (författare)
- Hyblean Association for Epidemiological Research
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- Ricceri, Fulvio (författare)
- University of Turin
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- Derksen, Jeroen W.G. (författare)
- University Medical Center Utrecht
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- Nøst, Therese Haugdahl (författare)
- UiT The Arctic University of Norway, Tromsø,Norwegian University of Science and Technology
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- Sandanger, Torkjel M. (författare)
- UiT The Arctic University of Norway, Tromsø
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- Borch, Kristin Benjaminsen (författare)
- UiT The Arctic University of Norway, Tromsø
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Quirós, J. Ramón (författare)
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- Castro-Espin, Carlota (författare)
- Catalan Institute of Oncology,Bellvitge Biomedical Research Institute,International Agency for Research on Cancer, World Health Organization
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- Sánchez, Maria José (författare)
- University of Granada,Andalusian School Of Public Health (EASP),CIBER Epidemiology and Public Health (CIBERESP)
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- Atxega, Amaia Aizpurua (författare)
- Biodonostia Health Research Institute
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- Cirera, Lluís (författare)
- Murcia Regional Health Council,University of Murcia,CIBER Epidemiology and Public Health (CIBERESP)
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- Guevara, Marcela (författare)
- Health Research Institute of Navarra (IDISNA),CIBER Epidemiology and Public Health (CIBERESP)
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- Manjer, Jonas (författare)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Surgery,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
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- Tin Tin, Sandar (författare)
- University of Oxford
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- Heath, Alicia (författare)
- Imperial College London
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- Touvier, Mathilde (författare)
- National Institute for Health and Medical Research, France
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- Goldberg, Marcel (författare)
- Université Paris Cité
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- Weiderpass, Elisabete (författare)
- International Agency for Research on Cancer, World Health Organization
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- Gunter, Marc J. (författare)
- Imperial College London,International Agency for Research on Cancer, World Health Organization
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- Freisling, Heinz (författare)
- International Agency for Research on Cancer, World Health Organization
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- Riboli, Elio (författare)
- Imperial College London
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- Ferrari, Pietro (författare)
- International Agency for Research on Cancer, World Health Organization
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(creator_code:org_t)
- 2024
- 2024
- Engelska.
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Ingår i: BMC Medicine. - 1741-7015. ; 22:1
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Healthy lifestyles are inversely associated with the risk of noncommunicable diseases, which are leading causes of death. However, few studies have used longitudinal data to assess the impact of changing lifestyle behaviours on all-cause and cancer mortality. Methods: Within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, lifestyle profiles of 308,497 cancer-free adults (71% female) aged 35–70 years at recruitment across nine countries were assessed with baseline and follow-up questionnaires administered on average of 7 years apart. A healthy lifestyle index (HLI), assessed at two time points, combined information on smoking status, alcohol intake, body mass index, and physical activity, and ranged from 0 to 16 units. A change score was calculated as the difference between HLI at baseline and follow-up. Associations between HLI change and all-cause and cancer mortality were modelled with Cox regression, and the impact of changing HLI on accelerating mortality rate was estimated by rate advancement periods (RAP, in years). Results: After the follow-up questionnaire, participants were followed for an average of 9.9 years, with 21,696 deaths (8407 cancer deaths) documented. Compared to participants whose HLIs remained stable (within one unit), improving HLI by more than one unit was inversely associated with all-cause and cancer mortality (hazard ratio [HR]: 0.84; 95% confidence interval [CI]: 0.81, 0.88; and HR: 0.87; 95% CI: 0.82, 0.92; respectively), while worsening HLI by more than one unit was associated with an increase in mortality (all-cause mortality HR: 1.26; 95% CI: 1.20, 1.33; cancer mortality HR: 1.19; 95% CI: 1.09, 1.29). Participants who worsened HLI by more than one advanced their risk of death by 1.62 (1.44, 1.96) years, while participants who improved HLI by the same amount delayed their risk of death by 1.19 (0.65, 2.32) years, compared to those with stable HLI. Conclusions: Making healthier lifestyle changes during adulthood was inversely associated with all-cause and cancer mortality and delayed risk of death. Conversely, making unhealthier lifestyle changes was positively associated with mortality and an accelerated risk of death.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Cancer
- Change score
- Composite score
- Healthy lifestyle index
- Longitudinal
- Mortality
- Prospective study
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Matta, Komodo
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Viallon, Vivian
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Botteri, Edoardo
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Peveri, Giulia
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Dahm, Christina
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Nannsen, Anne Øs ...
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visa fler...
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Olsen, Anja
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Tjønneland, Anne
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Elbaz, Alexis
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Artaud, Fanny
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Marques, Chloé
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Kaaks, Rudolf
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Katzke, Verena
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Schulze, Matthia ...
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Llanaj, Erand
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Masala, Giovanna
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Pala, Valeria
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Panico, Salvator ...
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Tumino, Rosario
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Ricceri, Fulvio
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Derksen, Jeroen ...
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Nøst, Therese Ha ...
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Sandanger, Torkj ...
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Borch, Kristin B ...
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Quirós, J. Ramón
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Castro-Espin, Ca ...
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Sánchez, Maria J ...
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Atxega, Amaia Ai ...
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Cirera, Lluís
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Guevara, Marcela
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Manjer, Jonas
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Tin Tin, Sandar
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Heath, Alicia
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Touvier, Mathild ...
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Goldberg, Marcel
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Weiderpass, Elis ...
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Gunter, Marc J.
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Freisling, Heinz
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Riboli, Elio
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Ferrari, Pietro
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
- Artiklar i publikationen
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BMC Medicine
- Av lärosätet
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Lunds universitet
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Karolinska Institutet