Sökning: onr:"swepub:oai:research.chalmers.se:1151215d-30a5-4758-afa0-d487ef2e21d3" > Biomaterial Integra...
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000 | 04634naa a2200517 4500 | |
001 | oai:research.chalmers.se:1151215d-30a5-4758-afa0-d487ef2e21d3 | |
003 | SwePub | |
008 | 220507s2022 | |||||||||||000 ||eng| | |
009 | oai:gup.ub.gu.se/316453 | |
024 | 7 | a https://research.chalmers.se/publication/5302332 URI |
024 | 7 | a https://doi.org/10.1002/mabi.2022000372 DOI |
024 | 7 | a https://gup.ub.gu.se/publication/3164532 URI |
040 | a (SwePub)cthd (SwePub)gu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a for2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a von Mentzer, Ula,d 1995u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)peiciute |
245 | 1 0 | a Biomaterial Integration in the Joint: Pathological Considerations, Immunomodulation, and the Extracellular Matrix |
264 | c 2022-04-27 | |
264 | 1 | b Wiley,c 2022 |
338 | a electronic2 rdacarrier | |
520 | a Defects of articular joints are becoming an increasing societal burden due to a persistent increase in obesity and aging. For some patients suffering from cartilage erosion, joint replacement is the final option to regain proper motion and limit pain. Extensive research has been undertaken to identify novel strategies enabling earlier intervention to promote regeneration and cartilage healing. With the introduction of decellularized extracellular matrix (dECM), researchers have tapped into the potential for increased tissue regeneration by designing biomaterials with inherent biochemical and immunomodulatory signals. Compared to conventional and synthetic materials, dECM-based materials invoke a reduced foreign body response. It is therefore highly beneficial to understand the interplay of how these native tissue-based materials initiate a favorable remodeling process by the immune system. Yet, such an understanding also demands increasing considerations of the pathological environment and remodeling processes, especially for materials designed for early disease intervention. This knowledge will avoid rejection and help predict complications in conditions with inflammatory components such as arthritides. This review outlines general issues facing biomaterial integration and emphasizes the importance of tissue-derived macromolecular components in regulating essential homeostatic, immunological, and pathological processes to increase biomaterial integration for patients suffering from joint degenerative diseases. | |
650 | 7 | a TEKNIK OCH TEKNOLOGIERx Maskinteknikx Produktionsteknik, arbetsvetenskap och ergonomi0 (SwePub)203072 hsv//swe |
650 | 7 | a ENGINEERING AND TECHNOLOGYx Mechanical Engineeringx Production Engineering, Human Work Science and Ergonomics0 (SwePub)203072 hsv//eng |
650 | 7 | a TEKNIK OCH TEKNOLOGIERx Annan teknikx Övrig annan teknik0 (SwePub)211992 hsv//swe |
650 | 7 | a ENGINEERING AND TECHNOLOGYx Other Engineering and Technologiesx Other Engineering and Technologies not elsewhere specified0 (SwePub)211992 hsv//eng |
650 | 7 | a TEKNIK OCH TEKNOLOGIERx Industriell bioteknikx Medicinsk bioteknik0 (SwePub)209082 hsv//swe |
650 | 7 | a ENGINEERING AND TECHNOLOGYx Industrial Biotechnologyx Medical Biotechnology0 (SwePub)209082 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Biomaterialvetenskap0 (SwePub)304032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Biomaterials Science0 (SwePub)304032 hsv//eng |
653 | a rheumatoid arthritis | |
653 | a immune systems | |
653 | a osteoarthritis | |
653 | a cartilage | |
653 | a extracellular matrix | |
653 | a biomaterials | |
653 | a implants | |
700 | 1 | a Corciulo, Carmenu Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Rheumatology and Inflammation Research4 aut0 (Swepub:gu)xcorca |
700 | 1 | a Stubelius, Alexandra,d 1983u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)karlstra |
710 | 2 | a Chalmers tekniska högskolab Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning4 org |
773 | 0 | t Macromolecular Bioscienced : Wileyg 22:7q 22:7x 1616-5195x 1616-5187 |
856 | 4 | u https://research.chalmers.se/publication/530233/file/530233_Fulltext.pdfx primaryx freey FULLTEXT |
856 | 4 8 | u https://research.chalmers.se/publication/530233 |
856 | 4 8 | u https://doi.org/10.1002/mabi.202200037 |
856 | 4 8 | u https://gup.ub.gu.se/publication/316453 |
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