| 1. |
- Taube, Amelie, 1966-, et al.
(författare)
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Trabeculectomy with an active postoperative regimen : results and resource utilization
- 2009
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Ingår i: Acta Ophthalmplogica. - : Wiley. - 0001-639X .- 1755-375X .- 1755-3768. ; 87:5, s. 524-528
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To evaluate intraocular pressure (IOP) and resource utilization after trabeculectomy, using an active postoperative regimen, in a Swedish population. METHODS: A retrospective analysis was performed on the patient charts of all patients who underwent trabeculectomy in a Swedish university hospital during 1 year (November 2000-December 2001). Trabeculectomy was performed in 34 eyes and trabeculectomy in combination with phacoemulsification in 10 eyes. Intraocular pressure, visual acuity, complications and numbers of injections of 5-fluorouracil, suture removal, needling procedures and visits to ophthalmologists were recorded for 2 years. RESULTS: Mean IOP before surgery was 30.4 mmHg (standard deviation [SD] 9.5) in eyes with capsular glaucoma and 28.7 mmHg (SD 9.3) in eyes with primary open-angle glaucoma. Mean IOP after 2 years was 15.3 mmHg (SD 3.9) in all eyes. Intraocular pressure of < 18 mmHg was achieved in 65% of the eyes after 2 years, as was IOP < or = 13 mmHg in 37%. Flap or suture manipulation was performed in 41 of 44 eyes. Needling procedures were carried out a mean of 2.3 times in 31 eyes. The mean number of visits to an ophthalmologist was 14.1 during the first postoperative year and 4.4 during the second. CONCLUSIONS: The results were encouraging, with few complications and modest resource utilization.
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| 2. |
- Airaksinen, P J, et al.
(författare)
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Visual field and retinal nerve fibre layer in early glaucoma after optic disc haemorrhage
- 1983
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 61:2, s. 94-186
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Tidskriftsartikel (refereegranskat)abstract
- Computerized visual field testing with the Competer automatic perimeter including automatic profile perimetry revealed early glaucomatous field loss in 9 of 10 eyes with photographically demonstrable retinal nerve fibre layer (RNFL) defects after optic disc haemorrhages despite the fact than conventional routine perimetry had failed to do so. In 7 of these cases the Competer central pattern test was abnormal; in 2 cases field defects could be shown only when automatic high-resolution static profile perimetry was performed and directed according to the information present in wide-angle RNFL photographs. A field defect was also found in one of five eyes with no photographic RNFL changes. Visual field defects seem to occur in a higher proportion of cases with RNFL defects than was previously thought, but they can be very subtle and hard to find. There are, however, cases where in spite of the presence of an indisputable RNFL defect no visual field defects can be shown even with painstaking technique and conversely field defects may be present without RNFL defects. Automatic perimetry and RNFL photography complement each other in early detection and quantitation of glaucomatous damage.
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| 3. |
- Alm, Albert
(författare)
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Effects of norepinephrine, angiotensin, dihydroergotamine, papaverine, isoproterenol, histamine, nicotinic acid, and xanthinol nicotinate on retinal oxygen tension in cats
- 1972
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 50:5, s. 707-719
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Tidskriftsartikel (refereegranskat)abstract
- The oxygen tension in the vitreous body close to the retina, PvrO2, was determined continuously in cats. The effects on PvrO2 of intraarterial injections of various vasoactive drugs were determined. The vasoconstrictors norepinephrine, angiotensin and dihydroergotamine did not change PvrO2 in five cats. The same result was obtained with the vasodilators isoproterenol, histamine and xanthinol nicotinate in five cats, and with nicotinic acid in six cats, while papaverine invariably increased PvrO2 in seven cats when injected intraarterially and in two cats when injected intravenously. It is suggested that the ability to penetrate the blood-retinal barrier may play an important role in determining the effect of vaso-active drugs on retinal blood flow.
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| 4. |
- Asman, P, et al.
(författare)
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Weighting according to location in computer-assisted glaucoma visual field analysis
- 1992
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 70:5, s. 8-671
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Tidskriftsartikel (refereegranskat)abstract
- In recent years several aids for automated interpretation of visual field data have been suggested. We believed that incorporation of thorough knowledge of normal visual field variability would allow improvements in the performance of such aids since more attention would be paid to field results in areas with low physiological variability. Two visual field models for classification of fields in glaucoma based on comparisons of sensitivity values in the upper and lower hemifields and on analysis of test point clusters with diminished sensitivity were compared. Both models were constructed using logistic regression analysis in 101 normal eyes and 101 eyes with glaucoma. The first, more traditional model assumed Gaussian distributions of deviations from age-corrected normal thresholds and constant variability across the field (non-weighted model). The second model took into account empirically determined variability of pointwise threshold results and of cluster volumes in various visual field regions (weighted model). The two models were subsequently tested on an independent material of 163 normal eyes and 76 eyes with glaucoma. The weighted model gave significantly better classification of the fields in both materials. Accounting for physiological threshold variability can offer significant advantages in the construction of perimetric analysis aids for detection of glaucoma.
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| 5. |
- Dyster-Aas, K, et al.
(författare)
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Computerized visual field screening in the management of patients with ocular hypertension
- 1980
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 58:6, s. 918-928
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Tidskriftsartikel (refereegranskat)abstract
- Visual field testing which the Computer fully automatic computerized perimeter (Heijl & Krakau 1975) employing a supra-liminal screening test procedure was used in a material of 1013 eyes with ocular hypertension in which earlier routine perimetry (kinetic and static) on the Goldmann perimeter had yielded a normal result. The automatic screening was repeated if positive, and manual control perimetry was used in order to confirm or reject identified field defects. This procedure revealed field defects that could be confirmed at both automatic and manual perimetry in 3.6% of the eyes. In the control group the incidence of field defects found at manual perimetry during the same time interval was calculated at 0.4%. Thus automatic screening revealed several times more field defects than manual routine perimetry. Eyes in which repeated automatic screening had indicated defects which manual control perimetry failed to confirm, showed a high percentage of field loss at later follow-up. The results are discussed, and the conclusion is drawn that automatic screening is clearly superior to manual routine perimetry used at present. The most practical solution in many eye departments would be to use a computerized perimeter for the visual field screening of glaucoma suspects.
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| 6. |
- Heijl, A, et al.
(författare)
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An automatic static perimeter, design and pilot study
- 1975
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 53:3, s. 293-310
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Tidskriftsartikel (refereegranskat)abstract
- An instrument for automatic static perimetry at 14 points across a meridian was constructed and used in a pilot study. The machine was controlled by a computer and the subjects responded to the light stimuli by pressing one of two push-buttons. Most people investigated readily understood the rules at testing. "Blunders" made by the subject were, however, so common, that allowance had to be made in the test programme for a number of mistakes. The test stimuli should be exposed in random order. When the zone of uncertain seeing is wide - this occurs especially in untrained subjects - a simple test logic gives a fairly large variation. An improvement in reproducibility is then obtained by applying a more complicated logic, though at the cost of an increased duration of the test session.
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| 7. |
- Heijl, A
(författare)
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Computer test logics for automatic perimetry
- 1977
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 55:5, s. 53-837
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Tidskriftsartikel (refereegranskat)abstract
- Using an automatic computerized perimeter developed by Heijl & Krakau (1975b) three different perimetric test logics, one simple (I) and two more complicated and time-consuming (II & III) were investigated in practical experiments on healthy normal test subjects and patients and in computer simulated tests. The patients either had a verified diagnosis of glaucoma or glaucoma was suspected. The best consistency in measured thresholds was obtained with test logic II, in which an averaging procedure is used. The variation of the results was larger in pathological than in normal visual fields. All test logics investigated readily detected the pathological field defects, but blind spots could easier pass unrecognized with the simplest logic than with the other two logics. The conclusion is drawn that a simple test logic can be used for perimetry in glaucoma suspects if no visual field defect has previously been documented. For the follow-up of pathological fields a fairly complicated test logic, e.g. using averaging, is preferable.
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| 8. |
- Heijl, A
(författare)
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Computerized perimetry in glaucoma management
- 1989
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 67:1, s. 1-12
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Forskningsöversikt (refereegranskat)abstract
- The present article discusses the role of computerized perimetry in the management of patients with suspect and manifest glaucoma. The value of visual field examination is compared to that of inspection and photography of the optic disc and to some extent to retinal nerve fibre layer photography. Computerized perimetry is related to standard manual visual field examination. Guidelines are offered for the choice of test programs and for the interpretation of results.
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| 9. |
- Heijl, A
(författare)
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Lack of diffuse loss of differential light sensitivity in early glaucoma
- 1989
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 67:4, s. 60-353
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Tidskriftsartikel (refereegranskat)abstract
- We studied the differential light sensitivity in 83 patients who were prospectively followed with computerized threshold preimetry and optic disc pathography because of suspect glaucoma. Eyes with media opacities were excluded from the analysis. Fourteen eyes developed progressive optic disc cupping and/or localized visual field loss. In this glaucoma group light sensitivity in the 10 best points in the visual field did not deviate more from estimated age-corrected standard values than in the remaining groups of 115 eyes with increased intraocular pressure and 18 normotensive eyes. The results do not support the concept that diffuse loss of differential light sensitivity should be common in early glaucoma.
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| 10. |
- Heijl, A
(författare)
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Time changes of contrast thresholds during automatic perimetry
- 1977
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Ingår i: Acta Ophthalmologica. - : Wiley. - 0001-639X .- 1755-375X. ; 55:4, s. 696-708
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Tidskriftsartikel (refereegranskat)abstract
- Contrast thresholds were continuously recorded in six points of the visual field through a repetitive up-and-down staircase method using the automatic perimeter developed by Heijl & Krakau (1975b). The uninterrupted sessions lasted about 30 min. Nineteen patients with a verified diagnosis of glaucoma, or in whom glaucoma was suspected, and twelve healthy normal subjects were tested. With increasing test time, a decreased contrast sensitivity was found. In most subjects the mean threshold increment was small (less than 1.5 dB). The threshold increments were larger in the patient group than in the normal subjects--many test points showing increments of 6-10 dB during the test session. Such a large deterioration of sensitivity was most common in eyes with visual field defects. Test points which showed large threshold increments were often situated in the vicinity of documented visual field defects. In eyes with pathological visual fields, the short-term variation increased with increasing test time. An impairment of fixation with increasing test time was found in the patient group.
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