| 1. |
- Bisgin, Atil, et al.
(författare)
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Serum soluble tumour necrosis factor related apoptosis-inducing ligand level and peripheral eosinophil count in patients with nasal polyposis
- 2015
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Ingår i: Journal of Laryngology and Otology. - : Cambridge University Press (CUP): STM Journals. - 0022-2151 .- 1748-5460. ; 129:3, s. 250-253
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Tidskriftsartikel (refereegranskat)abstract
- Background: Nasal polyposis is one of the most common inflammatory pathologies of the nasal cavity. Eosinophilic inflammation plays an important role in the pathogenesis. This study aimed to investigate soluble tumour necrosis factor related apoptosis-inducing ligand levels and eosinophil count in nasal polyposis patients. Methods: The study was performed on 24 adult nasal polyposis patients and 24 age-matched healthy individuals. The patients had not received any medical or surgical treatment. Pre-operative computed tomography scans were assessed using the Lund-MacKay grading system, and soluble tumour necrosis factor related apoptosis-inducing ligand levels were measured with a sandwich enzyme-linked immunosorbent assay. Results: Compared with controls, eosinophil levels in nasal polyposis patients were increased (p = 0.024), but there was no significant difference in soluble tumour necrosis factor related apoptosis-inducing ligand levels (p = 0.529). The Lund-Mackay mean grading was 12.43 +/- 6.9. There was no correlation between soluble tumour necrosis factor related apoptosis-inducing ligand level and Lund-Mackay grading and eosinophil count. Conclusion: There was no relationship between soluble tumour necrosis factor related apoptosis-inducing ligand level and blood eosinophil or clinical markers; however, soluble tumour necrosis factor related apoptosis-inducing ligand level remains of interest for future studies.
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| 2. |
- Blomstedt, Patric
(författare)
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Tracheostomy in ancient Egypt
- 2014
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Ingår i: Journal of Laryngology and Otology. - 0022-2151 .- 1748-5460. ; 128:8, s. 665-668
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Forskningsöversikt (refereegranskat)abstract
- It has often been reported that the ancient Egyptians performed tracheostomies. An analysis of this claim demonstrates it to be founded on only two depictions from the Protodynastic period (thirty-first century BC). These depictions are difficult to reconcile with tracheostomy from an anatomical point of view and can more easily be explained as human sacrifices. Considering that Egyptian surgery included only minor procedures even at its zenith during later dynastic periods, it is difficult to imagine that they would have developed such an advanced procedure at such an early date.
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| 3. |
- Diamant, H, et al.
(författare)
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Swedish otorhinolaryngology (ORL) 1880-1920
- 2005
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Ingår i: The Journal of laryngology and otology. Supplement. - : Cambridge University Press (CUP). - 0144-2945 .- 0022-2151 .- 1748-5460. ; 119:30, s. 104-106
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Emgård, Per, et al.
(författare)
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A group III steroid solution without antibiotic components : an effective cure for external otitis.
- 2005
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Ingår i: Journal of Laryngology and Otology. - : Cambridge University Press (CUP). - 0022-2151 .- 1748-5460. ; 119:5, s. 342-7
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Tidskriftsartikel (refereegranskat)abstract
- The present study was undertaken to compare the clinical benefits of prescribing ear drops containing 0.05% solution of betamethasone dipropionate (BD), and ear drops containing hydrocortisone with oxytetracycline hydrochloride and polymyxin B (HCPB), for topical treatment of external otitis. Fifty-one patients were enrolled in this open randomized, parallel-group, multicentre study, performed in eight different ENT departments. The patients were randomly assigned to one of the two treatment groups: BD (n = 26) and HCPB (n = 25). Only ENT specialists investigated the patients. Bacterial and fungal cultures were raised on days 1 and 11, using swabbed material from ear canals. Twice daily the patients recorded their symptoms during the acute phase, using special diary cards.BD proved a significantly more effective cure than HCPB during the acute phase of external otitis and afforded a lower relapse frequency during a six-month follow-up period. The patients of the BD group were significantly less troubled by itching (p < 0.01) than those in the HCPB group. On day 11, at the end of the acute phase, growth of bacteria (p = 0.03) and fungi (p < 0.01) was less frequent in the BD group than in the HCPB group. No serious adverse events occurred, and those minor events observed were comparable between the two groups.Our conclusion is that the group III steroid solution, BD, cured the external otitis more effectively than did the HCPB solution, whether infected by bacteria or by fungi. No difference was evident regarding adverse effects. Furthermore, price favours a solution without any antibiotic component. In view of these observations, a group III steroid solution ought to be the preferred remedy for external otitis, whether infected or not.
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| 5. |
- Geneid, A., et al.
(författare)
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Union of the European Phoniatricians position statement on the exit strategy of phoniatric and laryngological services: staying safe and getting back to normal after the peak of coronavirus disease 2019 (issued on 25th May 2020)
- 2020
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Ingår i: Journal of Laryngology and Otology. - : CAMBRIDGE UNIV PRESS. - 0022-2151 .- 1748-5460. ; 134:8, s. 661-664
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Tidskriftsartikel (refereegranskat)abstract
- Background The following position statement from the Union of the European Phoniatricians, updated on 25th May 2020 (superseding the previous statement issued on 21st April 2020), contains a series of recommendations for phoniatricians and ENT surgeons who provide and/or run voice, swallowing, speech and language, or paediatric audiology services. Objectives This material specifically aims to inform clinical practices in countries where clinics and operating theatres are reopening for elective work. It endeavours to present a current European view in relation to common procedures, many of which fall under the aegis of aerosol generating procedures. Conclusion As evidence continues to build, some of the recommended practices will undoubtedly evolve, but it is hoped that the updated position statement will offer clinicians precepts on safe clinical practice.
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| 6. |
- Hallgren, Frida, et al.
(författare)
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Antibiotics in treatment of peritonsillar infection: clindamycin versus penicillin
- 2021
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Ingår i: Journal of Laryngology and Otology. - : Cambridge University Press (CUP). - 0022-2151. ; 135:1, s. 64-69
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Tidskriftsartikel (refereegranskat)abstract
- Objective This study aimed to compare antibiotic treatment with clindamycin versus penicillin V or G in terms of time to recovery and recurrence in patients with peritonsillar infection, including both peritonsillar cellulitis and peritonsillar abscess. Method This retrospective cohort study examined the records of 296 patients diagnosed with peritonsillar infection. Based on the ENT doctor's choice of antibiotics, patients were divided into clindamycin and penicillin groups. Results Mean number of days in follow up was 3.5 days in the clindamycin group and 3.4 days in the penicillin group. The recurrence rate within 2 months was 7 per cent in the clindamycin group and 4 per cent in the penicillin group. Conclusion This study found no significant differences in either recovery or recurrence between the groups. This supports the use of penicillin as a first-line treatment, considering the greater frequency of adverse effects of clindamycin shown in previous studies, as well as its profound collateral damage on the intestinal microbiota, resulting in antibiotic resistance.
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| 7. |
- Heo, S J, et al.
(författare)
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Stability measurements of craniofacial implants by means of resonance frequency analysis. A clinical pilot study.
- 1998
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Ingår i: The Journal of laryngology and otology. - : Cambridge University Press (CUP). - 0022-2151 .- 1748-5460. ; 112:6, s. 537-42
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Tidskriftsartikel (refereegranskat)abstract
- Nineteen patients previously treated with 52 implants for anchorage of craniofacial prostheses were subjected to implant stability measurements by means of resonance frequency analysis (RFA), six months to 15 years after implant placement. The resonance frequency (RF) of a transducer attached to the implant abutment was measured by using a frequency response analyser, a personal computer (PC) and dedicated software. Statistically significant higher RF values were seen for implants in the temporal bone as compared to implants in the nose and periorbital regions. There was a positive correlation with time since implant placement for the period from six months up to seven years. It was concluded that the preliminary results suggest that implant stability increases with time and that implants in temporal bone are more stable than implants in the bone in the nose and periorbital regions, probably reflecting differences in bone density.
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| 8. |
- Hydén, Dag, 1945-, et al.
(författare)
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Ear involvement in ligneous conjunctivitis : A rarity or an under-diagnosed condition?
- 2002
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Ingår i: Journal of Laryngology and Otology. - : Cambridge University Press (CUP). - 0022-2151 .- 1748-5460. ; 116:6, s. 482-487
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Tidskriftsartikel (refereegranskat)abstract
- Conjunctivitis lignosa, a rare affliction of the conjunctiva, is sometimes associated with other disturbances. We present two children with concurrent conjunctivitis lignosa and ear involvement. In these two cases, there were histopathologically verified ligneous changes of the middle ears. Routine haematoxylin and eosin, van Gieson, periodic acid-Schiff (PAS) and alcian blue staining of specimens from the eyes and middle ears revealed findings typical for ligneous conjunctivitis. In addition, new histochemical and immunohistochemical studies for glycosaminoglycans on specimens from the eyes and middle ears showed that the accumulations of the amorphous, cell-deficient material stained strongly but heterogeneously for hyaluronic acid and weakly but uniformly for keratin sulphate. The staining for other glycosaminoglycans, e.g. chondroitin-4-sulphate and dermatan sulphate was confined to vessels and areas rich in collagen fibres and fibroblasts. In patients with conjunctivitis lignosa, the ear involvement may remain undiagnosed due to its resemblance to secretory otitis media with effusion. Since isolated ear involvement may occur, we advocate biopsies for routine haematoxylin and eosin, and specific staining for hyaluronic acid and keratin sulphate, also in children with protracted, refractory otitis media with atypical effusion.
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| 9. |
- Knutsson, J, et al.
(författare)
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Five-year results for use of single-flanged tympanostomy tubes in children
- 2008
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Ingår i: Journal of Laryngology and Otology. - 0022-2151 .- 1748-5460. ; 122, s. 584-589
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Tidskriftsartikel (refereegranskat)abstract
- Aims: To assess the five-year outcome of the use of single-flanged tympanostomy tubes in children,including the time to extrusion, rate of retained tubes and rate of persistent perforation. Materials and methods: The medical records relating to 640 single-flanged tympanostomy tubesintended for short-term use in paediatric patients were retrospectively reviewed. Results and analysis: We found that 36.4 per cent of the tubes had extruded within 12 months and 71.0per cent within 24 months. Results showed that 14.1 per cent of the tubes had been removed because ofprolonged retention, with a mean time to removal of 38.9 months. The time to extrusion was longerand the rate of retained tubes was higher than those reported for several other short-term tubes. Wefound that 4.5 per cent of tube insertions had resulted in a persistent perforation, a higher percentagethan previously reported for other tubes intended for short-term use. Within five years of tubeinsertion, 70.5 per cent of the tympanic membranes had normalised.
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| 10. |
- Korres, S., et al.
(författare)
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Prognosis of patients with idiopathic sudden hearing loss : role of vestibular assessment
- 2011
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Ingår i: Journal of Laryngology and Otology. - : Cambridge University Press. - 0022-2151 .- 1748-5460. ; 125:3, s. 251-257
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To evaluate the correlation between caloric and vestibular evoked myogenic potential test results, initial audiogram data, and early hearing recovery, in patients with idiopathic sudden hearing loss.Materials and methods: One hundred and four patients with unilateral idiopathic sudden hearing loss underwent complete neurotological evaluation. Results for vestibular evoked myogenic potential and caloric testing were compared with patients' initial and final audiograms.Results: Overall, abnormal vestibular evoked myogenic potential responses occurred in 28.8 per cent of patients, whereas abnormal caloric test results occurred in 50 per cent. A statistically significant relationship was found between the type of inner ear lesion and the incidence of profound hearing loss. Moreover, a negative correlation was found between the extent of the inner ear lesion and the likelihood of early recovery.Conclusion: In patients with idiopathic sudden hearing loss, the extent of the inner ear lesion tends to correlate with the severity of cochlear damage. Vestibular assessment may be valuable in predicting the final outcome.
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