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- Aspán, Anna, et al.
(author)
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Genotypic variation among Staphylococcus aureus isolates from cases of clinical mastitis in Swedish dairy cows
- 2010
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In: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 185, s. 188-192
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Journal article (peer-reviewed)abstract
- The main aim of this study was to examine genotypic diversity of 82 Staphylococcus aureus isolates from cases of acute clinical mastitis in cattle using pulsed-field gel electrophoresis, and to investigate pulso-type differences between geographical regions of Sweden. The work also investigated haemolysis type (alpha, alpha beta), beta-lactamase production, and the association between S. aureus pulsotypes and breed, parity and presence of teat lesions. All isolates came from different farms.In total, 25 pulsotypes were found, but most only once or twice. The most common pulsotype accounted for 26% of the isolates and was found in all regions. The distribution of pulsotypes in the southern region of the country differed from the northern and middle regions. alpha beta- or alpha-Haemolysis was found in 66% and 34% of the isolates, respectively, and beta-lactamase production was found in 9% of the isolates. Variation in haemolysis type or beta-lactamase production was found within some pulsotypes. The results indicate that some pulsotypes have spread widely between herds within the country. (C) 2009 Elsevier Ltd. All rights reserved.
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- Axling, Johanna, et al.
(author)
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Use of diagnostic reports to estimate prevalence and distribution of skeletal lesions in young Thoroughbreds
- 2016
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In: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 214, s. 72-76
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Journal article (peer-reviewed)abstract
- Diagnostic reports written to assist stud managers in the sale of young Thoroughbreds have not previously been used as a data source for the study of skeletal lesions. However, analyses of these reports may provide efficient and cost-effective insights into the prevalence and distribution of skeletal lesions within a population. Diagnostic reports written by veterinarians were acquired from Thoroughbred stud managers in Australia and New Zealand. The reports were based on approximately 1300 sets of weanling and yearling radiographs taken between 2002 and 2007. The prevalence and anatomical distribution of skeletal lesions in weanlings (299 horses) and yearlings (1004 horses) were determined from these reports. Overall, 69.9% of weanlings and 64.5% of yearlings were reported as having one or more skeletal lesions. Diagnostic reports in weanlings were a strong indication of what was likely to be seen in subsequent yearling reports. These diagnostic reports are typically used by stud managers in the sales process and the potential drawback is that some categories of skeletal lesions may be under-reported. However, there was substantial agreement between the prevalence and distribution of several skeletal lesions reported in this study and those previously reported from direct evaluation of radiographs for Australian and New Zealand Thoroughbred yearlings. Strong agreement was found for osteophytes, enthesiophytes and other modelling in the hocks, and for lesions in the hind fetlocks and stifles. This indicates that written diagnostic reports are a useful and a reliable source of data for the study of some skeletal lesions in young Thoroughbred horses. (C) 2016 Elsevier Ltd. All rights reserved.
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- Bergknut, Niklas
(author)
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Biomechanical evaluation of a novel nucleus pulposus prosthesis in canine cadaveric spines
- 2012
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In: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 192, s. 199-205
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Journal article (peer-reviewed)abstract
- Partial disc replacement is a new surgical technique aimed at restoring functionality to degenerated intervertebral discs (IVDs). The aim of the present study was to assess biomechanically the behaviour of a novel nucleus pulposus prosthesis (NPP) in situ and its ability to restore functionality to the canine IVD after nuclectomy alone or after combined dorsal laminectomy and nuclectomy. Nine canine T13-L5 specimens (L2L3 group) and 10 L5-Cd1 specimens (LS group) were tested biomechanically in the native state, after nuclectomy (L2L3 group) or after combined dorsal laminectomy and nuclectomy (LS group), and after insertion of the NPP. Range of motion (ROM), neutral zone (NZ), and neutral zone stiffness (NZS) were determined in flexion/extension, lateral bending, and axial rotation.Nuclectomy alone and combined dorsal laminectomy and nuclectomy caused significant instability in all motion directions. Implantation of the NPP resulted in significant restoration of the parameters (ROM, NZ, and NZS) towards the native state; however, fragmentation/herniation of the NPP occurred in 47% of the cases. In conclusion, the NPP has the ability to improve functionality of the nuclectomized canine IVD. The high rate of NPP failure requires modifications directed at the integrity of the NPP and its confinement to the nuclear cavity. (C) 2011 Elsevier Ltd. All rights reserved.
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- Bergknut, Niklas, et al.
(author)
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Intervertebral disc degeneration in the dog. Part 1: Anatomy and physiology of the intervertebral disc and characteristics of intervertebral disc degeneration
- 2013
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In: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 195, s. 282-291
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Research review (peer-reviewed)abstract
- Intervertebral disc (IVD) degeneration is common in dogs and can give rise to a number of diseases, such as IVD herniation, cervical spondylomyelopathy, and degenerative lumbosacral stenosis. Although there have been many reports and reviews on the clinical aspects of canine IVD disease, few reports have discussed and reviewed the process of IVD degeneration. In this first part of a two-part review, the anatomy, physiology, histopathology, and biochemical and biomechanical characteristics of the healthy and degenerated IVD are described. In Part 2, the aspects of IVD degeneration in chondrodystrophic and non-chondrodystrophic dog breeds are discussed in depth
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- Bergknut, Niklas, et al.
(author)
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Intervertebral disc degeneration in the dog. Part 2: Chondrodystrophic and non-chondrodystrophic breeds
- 2013
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In: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 195, s. 292-299
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Journal article (peer-reviewed)abstract
- Dogs can be grouped into two distinct types of breed based on the predisposition to chondrodystrophy, namely, non-chondrodystrophic (NCD) and chondrodystrophic (CD). In addition to a different process of endochondral ossification, NCD and CD breeds have different characteristics of intravertebral disc (IVD) degeneration and IVD degenerative diseases. The anatomy, physiology, histopathology, and biochemical and biomechanical characteristics of the healthy and degenerated IVD are discussed in the first part of this two-part review. This second part describes the similarities and differences in the histopathological and biochemical characteristics of IVD degeneration in CD and NCD canine breeds and discusses relevant aetiological factors of IVD degeneration. (C) 2012 Elsevier Ltd. All rights reserved.
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- Bergknut, Niklas, et al.
(author)
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Intervertebral disc disease in dogs - Part 1: A new histological grading scheme for classification of intervertebral disc degeneration in dogs
- 2013
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In: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 195, s. 156-163
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Journal article (peer-reviewed)abstract
- Three independent observers evaluated 35 IVDs at different stages of degeneration using the scheme. Glycosaminoglycan contents of the nucleus pulposus and macroscopic grading according to Thompson, which are considered 'gold standards' for IVD degeneration, were used to validate the scheme. Reproducibility was assessed by analysing the inter-observer reliability of all individual variables of the grading scheme, using a weighted kappa analysis. Significant correlations were found between Thompson grading and total histological score (r = 0.94; P < 0.01) and between glycosaminoglycan content and total histological score (r = -0.72; P < 0.01). Most individual histological variables showed 'moderate' to 'almost perfect' inter-observer reliability. The high correlation with the gold standards in combination with the high reproducibility indicates that the proposed histological grading scheme is reliable and objective for classification of IVD degeneration in both chondrodystrophic and non-chondrodystrophic dog breeds. (C) 2012 Elsevier Ltd. All rights reserved.
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- Bergsten, Christer
(author)
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The effect of an acidified, ionized copper sulphate solution on digital dermatitis in dairy cows
- 2012
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In: Veterinary Journal. - : Elsevier BV. - 1090-0233 .- 1532-2971. ; 193, s. 659-663
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Journal article (peer-reviewed)abstract
- At the start of the study 21/110 cows had ulcerative DD lesions with 10 on the left hind foot, 8 on the right and 3 on both. These lesions, as well as any new lesions which arose during the study, were treated with chlortetracycline spray. During the study 440 observations were made and seven new DD lesions were recorded on left feet (copper treated) and 20 on right feet (formalin treated). Based on survival analysis, the risk of developing a new ulcerative DD lesion on copper-treated (left hind) feet was almost three times less (RR = 0.37, 95% CI 0.16-0.91) than formalin-treated (right hind) feet. Cure rates of DD lesions were not different between copper and formalin. (C) 2012 Elsevier Ltd. All rights reserved.
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