1. |
- Babakinejad, Babak, et al.
(författare)
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Local delivery of molecules from a nanopipette for quantitative receptor mapping on live cells
- 2013
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Ingår i: Analytical Chemistry. - : American Chemical Society (ACS). - 1520-6882 .- 0003-2700. ; 85:19, s. 42-9333
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Tidskriftsartikel (refereegranskat)abstract
- Using nanopipettes to locally deliver molecules to the surface of living cells could potentially open up studies of biological processes down to the level of single molecules. However, in order to achieve precise and quantitative local delivery it is essential to be able to determine the amount and distribution of the molecules being delivered. In this work, we investigate how the size of the nanopipette, the magnitude of the applied pressure or voltage, which drives the delivery, and the distance to the underlying surface influences the number and spatial distribution of the delivered molecules. Analytical expressions describing the delivery are derived and compared with the results from finite element simulations and experiments on delivery from a 100 nm nanopipette in bulk solution and to the surface of sensory neurons. We then developed a setup for rapid and quantitative delivery to multiple subcellular areas, delivering the molecule capsaicin to stimulate opening of Transient Receptor Potential Vanilloid subfamily member 1 (TRPV1) channels, membrane receptors involved in pain sensation. Overall, precise and quantitative delivery of molecules from nanopipettes has been demonstrated, opening up many applications in biology such as locally stimulating and mapping receptors on the surface of live cells.
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2. |
- Chithra, G. K., et al.
(författare)
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Android application for ticket collector in trains
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 9:Special Issue 2, s. 1015-1022
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Tidskriftsartikel (refereegranskat)abstract
- The main objective of this android app is that the ticket collector checks the traveller price tag and updates the traveller list to the information whether or not the passengers are travelling in the train according to their tickets with their individual dates of a journey. This app starts with a login page. The ticket collector updates the user id and watchword manually to IRCTC and therefore the management stores his user-id and watchword within the information. So, the ticket collector 1st needs to login to the app together with his individual user-id and password. Then once logging in to the app, HOME page is displayed. during this page, the ticket collector needs to select the train range and so the date of journey and therefore the diary number and then submits this page. Then he gets the traveller list and therefore the ticket collector checks the traveller list and updates the list supported who is travelling. And at that time submits the checked traveller list and then it gets updated to the information. This app helps the ticket collector most. Some passengers take the general price tag and request ticket collector for the berth or seat within the reservation coach. So, at this time this app helps the ticket collector to look at the quantity of vacant seats. It reduces the looking out time for the ticket collector. the quantity of vacant seats is displayed once the ticket collector simply clicks the quantity of vacant seat availability option. The porter asks the traveller regarding his/her supply and destination that he needed the price tag. So, supported the traveller necessities the ticket collector chooses the supply and destination that the traveller desires the seat or berth. So, if the seats square measure vacant then the ticket collector checks the number to be paid by the traveller as fine and so asks the fine and if the traveller pays the fine to the ticket collector then he updates the traveller details who need the price tag and so he updates the traveller details to the database.
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3. |
- Mahajan, Anubha, et al.
(författare)
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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
- 2022
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Ingår i: Nature Genetics. - : Springer Nature. - 1061-4036 .- 1546-1718. ; 54:5, s. 560-572
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Tidskriftsartikel (refereegranskat)abstract
- We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the Diabetes Meta-Analysis of Trans-Ethnic association studies (DIAMANTE) Consortium. Multi-ancestry GWAS meta-analysis identified 237 loci attaining stringent genome-wide significance (P < 5 x 10(-9)), which were delineated to 338 distinct association signals. Fine-mapping of these signals was enhanced by the increased sample size and expanded population diversity of the multi-ancestry meta-analysis, which localized 54.4% of T2D associations to a single variant with >50% posterior probability. This improved fine-mapping enabled systematic assessment of candidate causal genes and molecular mechanisms through which T2D associations are mediated, laying the foundations for functional investigations. Multi-ancestry genetic risk scores enhanced transferability of T2D prediction across diverse populations. Our study provides a step toward more effective clinical translation of T2D GWAS to improve global health for all, irrespective of genetic background. Genome-wide association and fine-mapping analyses in ancestrally diverse populations implicate candidate causal genes and mechanisms underlying type 2 diabetes. Trans-ancestry genetic risk scores enhance transferability across populations.
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4. |
- Monika, K., et al.
(författare)
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Theft vehicle scheme using cloud computing techniques
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 9:Special Issue 2, s. 1023-1031
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Tidskriftsartikel (refereegranskat)abstract
- Due to proliferation in the metropolitan areas there existing problem of poor traffic congestion has grown at alarming event and it is not easy to find the stolen vehicles. So here we use Theft vehicle detection system for finding the theft vehicles using open source hardware of RASPBERRY PI.This system make use of RFID and embedded technology. Here each vehicle is placed with RFID tag. Whenever the RFID reader reads the RFID tag in the stolen vehicle it alert the traffic police and the signal will be automatically changed into red light until the vehicle is recovered from the stolen person. This is achieved by connecting cloud technology with server which is handle by the traffic police. When the traffic controller ensures that the particular vehicle is missed then, whenever that particular vehicle crossed by the any signal red light blinks automatically then cloud displays the message with vehicle number.By using this system, we can alert the signal and can easily find the stolen vehicle by tracking the RFID tag.
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5. |
- Razia Sulthana, A., et al.
(författare)
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Improvement on software testing techniques and tools
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 9:2 Special Issue, s. 1049-1058
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Tidskriftsartikel (refereegranskat)abstract
- Programming Testing is a procedure of discovering mistakes while executing a program with the goal that we get a zero deformity programming. It is gone for assessing the ability or ease of use of a program. Programming testing is an essential methods for getting to nature of programming. Despite the fact that a great deal of progressions have been done in formal strategies and check procedures, still we require programming to be completely tried before it could be dealt with to the client side. Subsequently there are various trying systems and instruments made to finish the undertaking. Programming testing is a vital zone of research and a great deal of advancement has been made in this field. In this paper, testing systems and apparatuses have been depicted. Some run of the mill most recent inquiries about have been outlined. Programming testing is increasing increasingly significance later on.
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6. |
- Sravani, K., et al.
(författare)
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Prescription viewer medcare application using android programming
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 9:Special Issue 2, s. 1360-1370
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Tidskriftsartikel (refereegranskat)abstract
- Living healthy is valuable to everyone. The expert assumes an essential part in sparing one's life by giving the therapeutic solution. The issues faced by patients in their busy lives can't keep the records of prescription safely, inappropriate and overdosed admission of meds furthermore neglecting to get meeting with specialist by going to doctor's facility. This can be explained by Medcare application using android programming. Android is the Operating System that has huge development as of late. The fundamental plan of this paper is to make patients sensible about the application, through which they can see the medicine given by specialist, set suggestion to planned drug, find adjacent drug stores and can alter next meeting with particular branch of specialist without going to healing facility.
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7. |
- Tamil Priya, D., et al.
(författare)
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Similarity based face identification using metrics analysis
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 9:Special Issue 2, s. 1371-1378
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Tidskriftsartikel (refereegranskat)abstract
- Confront acknowledgment framework is one of the biometrics strategies that are utilized as a part of assortment of uses utilizing the picture handling systems. Confront acknowledgment framework is produced utilizing the Mat lab condition with the systems took after by main segment investigation and the straight discriminant examination. The execution is measured utilizing the time rate, remove rate, pixel values and the element separated determination rate. The ideal acknowledgment is executed when the time traverse around half and the separation rate around the 90 %. What’s more, on account of pixel and determination, when the pixel qualities are expanding then the determination calculate ought to likewise be an expanding request. On the off chance that the removed element contains more pixels then the determination element is progressively that identifies with the quality in separating the element. The execution is measured utilizing the two distinctive programming metric techniques to be specific spearmen and Pearson metric. At that point the general measure is characterized by picking up with the two metric strategies. The execution is plotted utilizing the diagram to foresee the rate of time and extricated include.
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8. |
- Uma, K., et al.
(författare)
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A novel method for smart vehicle safety
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 2017:Special Issue 2, s. 1259-1269
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Tidskriftsartikel (refereegranskat)abstract
- This to a great extent reduces the manpower, saves time and operates efficiently without human intervention. With the advent in technology, the existing systems are developed to have in built intelligence. The proposed work to monitor the pressure of the vehicle tire using the Arduino, this will be very much helpful to avoid the burst of tire and to understand about the tire pressure under various load situation of a vehicle. fuel level and the location can be updated during abnormal condition using wireless technology. The accident can be monitored using the high level vibration sensor and if the accident has occurred in any location it can immediately inform to the nearby hospital or ambulance service, the location of the accident. It is tire pressure monitoring. Pressure sensor acts as a main role to monitor the pressure of the vehicle, and it reports to the owner of the vehicle when the pressure gets low with the help of GSM work. This GSM work and the pressure sensor is connected to the Arduino board with the help of connecting wires. It is fuel level monitoring. Fuel level sensor is used to monitor the fuel of the vehicle and when the fuel gets low a message is automatically sent to the owner of the vehicle with the help of GSM work. This GSM work and the fuel sensor is connected to the arduino board with the help of connecting wires. It is accident tracking and intimating to nearby hospital. If the accident happens to the vehicle, with the help of vibration sensor the accident is recorded. The vibration is transmitted to GPS, GPS tracks the location of the vehicle and sent to GSM. It sends message to the nearby hospital and the hospital management has to take the responsibility in taking patient to the hospital for treatment.
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9. |
- Uma, K., et al.
(författare)
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Scanned compound images using different compression techniques
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 9:Special Issue 2, s. 994-1000
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Tidskriftsartikel (refereegranskat)abstract
- This Paper involves a detailed study of different compression techniques of scanned compound images. A compound image is a different kind of image that contains text, natural image and graphic image. Some of the Image compression techniques which include DCT,JPEG, H.264,MMP AND APM-MMP have been reviewed and presented in this paper. Discrete cosine transform (DCT) is a method which compresses the compound image without any loss of data. To compress image DCT is computed using two dimensional functions (2D).Join Picture Expert Group(JPEG) is mostly used as standard format for compressed images. Due to loss of data the compressed image differs from the original image.H.264 is a video compression standard which is also capable of compressing a compound image.MMP is specifically calculated to encode separately the macro blocks information of text and image. Since complexity is high in these above techniques the proposed technique Adaptive Probability Model-MMP solves the limitations like redundant data removal and enhances the image quality. It also improves the encoding efficiency thus modifying the MMP’s character.
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10. |
- Uma, K., et al.
(författare)
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The challenges and issues on big data analytics
- 2017
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Ingår i: Journal of Advanced Research in Dynamical and Control Systems. - : Institute of Advanced Scientific Research, Inc.. - 1943-023X. ; 2017:Special Issue 2, s. 1242-1258
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Tidskriftsartikel (refereegranskat)abstract
- A tremendous store of terabytes of information is created every day from present day data frameworks and advanced innovations, for example, Internet of Things and cloud computing. Analysing of these terabytes of information requires a ton of activities at various levels to extract data from knowledge base. In this manner, big data examination is a momentum region of innovative work. The fundamental goal of this paper is to analyse the potential effect of big data challenges, open research issues, and different tools related with it. Accordingly, this article gives a stage to investigate big data information at various stages. It finally provides the researchers to develop the solution based upon their challenges and also provides research issues.
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