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Träfflista för sökning "WFRF:(Brito Thiago) "

Search: WFRF:(Brito Thiago)

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1.
  • Battarbee, Markus, et al. (author)
  • Helium in the Earth's foreshock : a global Vlasiator survey
  • 2020
  • In: Annales Geophysicae. - : Copernicus GmbH. - 0992-7689 .- 1432-0576. ; 38:5, s. 1081-1099
  • Journal article (peer-reviewed)abstract
    • The foreshock is a region of space upstream of the Earth's bow shock extending along the interplanetary magnetic field (IMF). It is permeated by shock-reflected ions and electrons, low-frequency waves, and various plasma transients. We investigate the extent of the He2+ foreshock using Vlasiator, a global hybrid-Vlasov simulation. We perform the first numerical global survey of the helium foreshock and interpret some historical foreshock observations in a global context. The foreshock edge is populated by both proton and helium field-aligned beams, with the proton foreshock extending slightly further into the solar wind than the helium foreshock and both extending well beyond the ultra-low frequency (ULF) wave foreshock. We compare our simulation results with Magnetosphere Multiscale (MMS) Hot Plasma Composition Analyzer (HPCA) measurements, showing how the gradient of suprathermal ion densities at the foreshock crossing can vary between events. Our analysis suggests that the IMF cone angle and the associated shock obliquity gradient can play a role in explaining this differing behaviour. We also investigate wave-ion interactions with wavelet analysis and show that the dynamics and heating of He2+ must result from proton-driven ULF waves. Enhancements in ion agyrotropy are found in relation to, for example, the ion foreshock boundary, the ULF foreshock boundary, and specular reflection of ions at the bow shock. We show that specular reflection can describe many of the foreshock ion velocity distribution function (VDF) enhancements. Wave-wave interactions deep in the foreshock cause de-coherence of wavefronts, allowing He2+ to be scattered less than protons.
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2.
  • Franco, Thiago A., et al. (author)
  • Reverse chemical ecology-based approach leading to the accidental discovery of repellents for Rhodnius prolixus, a vector of Chagas diseases refractory to DEET
  • 2018
  • In: Insect Biochemistry and Molecular Biology. - : Elsevier. - 0965-1748 .- 1879-0240. ; 103, s. 46-52
  • Journal article (peer-reviewed)abstract
    • Rhodnius prolixus is one of the most important vectors of Chagas disease in Central and South America for which repellents and attractants are sorely needed. Repellents like DEET, picaridin, and IR3535 are widely used as the first line of defense against mosquitoes and other vectors, but they are ineffective against R. prolixus. Our initial goal was to identify in R. prolixus genome odorant receptors sensitive to putative sex pheromones. We compared gene expression of 21 ORs in the R. prolixus genome, identified 4 ORs enriched in male (compared with female) antennae. Attempts to de-orphanize these ORs using the Xenopus oocyte recording system showed that none of them responded to putative sex pheromone constituents. One of the them, RproOR80, was sensitive to 4 compounds in our panel of 109 odorants, namely, 2-heptanone, gamma-octalactone, acetophenone, and 4-methylcychohexanol. Interestingly, these compounds, particularly 4-methylcyclohexanol, showed strong repellency activity as indicated not only by a significant decrease in residence time close to a host, but also by a remarkable reduction in blood intake. 4-Methylcyclohexanol-elicited repellency activity was abolished in RNAi-treated insects. In summary, our search for pheromone receptors led to the discovery of repellents for R. prolixus.
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