1. |
- Chen, Shuyun, et al.
(author)
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Random capillary glucose levels throughout pregnancy, obstetric and neonatal outcomes, and long-term neurodevelopmental conditions in children : a group-based trajectory analysis.
- 2023
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In: BMC Medicine. - : BioMed Central (BMC). - 1741-7015. ; 21:1
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Journal article (peer-reviewed)abstract
- BACKGROUND: Gestational diabetes mellitus (GDM) is associated with both short- and long-term risks, although it is unknown if risks vary by severity, timing, and duration of gestational hyperglycemia. We aimed to identify trajectories of random capillary glucose (RCG) levels throughout pregnancy and assess their associations with both obstetric/neonatal outcomes and children's risk of neurodevelopmental conditions (NDCs) (i.e., autism, intellectual disability, and attention-deficit/hyperactivity disorders [ADHD]).METHODS: A population-based cohort study was conducted involving 76,228 children born to 68,768 mothers without pregestational diabetes. Group-based trajectory modeling was utilized to identify distinct glucose trajectories across RCG values throughout the course of pregnancy. The associations between these trajectory groups and obstetric/neonatal outcomes as well as children's NDCs were then assessed using generalized estimating equation models with a logit link. The Benjamini-Hochberg (BH) procedure was employed to adjust P-values for multiple comparisons, controlling the false discovery rate (FDR).RESULTS: Five distinct glucose trajectory groups were identified, each with varying percentages diagnosed with GDM. Their associations with obstetric/neonatal outcomes as well as children's NDCs varied. For example, when compared to the "Persistently Low" group, other groups exhibited varying degrees of increased risk for large-for-gestational-age babies, with the exception of the "High in Early Pregnancy" group. Compared to the "Persistently Low" group, all other trajectory groups were associated with NDC outcomes, except the "High in Mid-Pregnancy" group. However, none of the associations with offspring NDCs remained significant after accounting for the FDR correction.CONCLUSIONS: Persistent high glucose levels or moderately elevated glucose levels throughout pregnancy, as well as transient states of hyperglycemia in early or mid-pregnancy, were found to be associated with increased risks of specific obstetric and neonatal complications, and potentially offspring NDCs. These risks varied depending on the severity, timing, duration, and management of hyperglycemia. The findings underscore the need for continuous surveillance and individualized management strategies for women displaying different glucose trajectories during pregnancy. Limitations such as potential residual confounding, the role of mediators, and small sample size should be addressed in future studies.
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2. |
- Flemme, Inger, 1947-, et al.
(author)
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Livskvalitet och upplevda chocker under ICD-behandling : en 5-års uppföljning
- 2004
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Conference paper (peer-reviewed)abstract
- ICD–behandling ökar överlevnaden hos patienter (pat), som har överlevt en malign ventrikulär tachyarytmi. Pats livskvalitet (QoL) har angivits variera betydande och långtidseffekterna är ännu mindre väl kända. Vi följde ett antal konsekutiva pat under minst 5 år med avseende på livskvaliteten.Metod. Pat undersöktes med MUIS-C (Mishel Uncertainty in Illness Scale – community version) och QLI-CV (Quality of Life Index – cardiac version) och multipel regressionsanalys användes hos 35 patienter. Formulären fylldes i vid tre tillfällen: före implantationen, efter 1 och 5 år. Pats egen uppfattning om antalet upplevda chocker oavsett anledning noterades.Patienter. Ur en grupp pat, som tidigare undersöktes efter 1 år, hade 39 pat överlevt med sin ICD i minst 5 år. Av dessa avböjde tre deltagande i uppföljningen utan orsak och en pga cancer. Alla pat hade fått sin ICD på indikationen sekundär prevention. Resultat. Under det första året rapporterade 13 pat totalt 79 chocker och 22 pat ingen chock. Tio pat hade ingen chock vare sig efter 1 eller 5 år, och deras QoL var likvärdig med dem som hade haft ≤5 chocker. Tre pat rapporterade ≥6 chocker och hade sänkt QoL. Mellan år 1 och 5 rapporterade 20 pat 94 shocker och 15 pat ingen shock. Det var ingen skillnad mellan pat med eller utan chocker i deras QoL år 5 vs. år 1. Pat med chocker blev mindre besvärade med tiden.QoL var generellt sänkt år 1 vs baseline. En försämring i den socio-ekonomiska domänen sågs år 1 men var förbättrad år 5. En försämring i familjedomänen var oförändrad vid 1 och 5 år vs. baseline. En förbättring av otrygghet noterades vid 5 år vs år 1.Konklusioner. Pat med ICD mådde bättre år 5 än år 1 efter implantationen. Livskvaliteten var rimligt god 5 år efter implantationen och pat kände sig mer trygga och upplevde sin ICD som en livräddare. Pat med många chocker under det första året mådde sämre än övriga. Under resten av observationsperioden var chocktätheten lägre, möjligen delvis pga farmakologisk behandling, och pat upplevde mindre besvär av chockerna.
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3. |
- Flemme, Inger, et al.
(author)
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Long-term quality of life and uncertainty in patients living with an implantable cardioverter defibrillator.
- 2005
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In: Heart & lung : the journal of critical care. - St. Louis, MO : Elsevier BV. - 0147-9563 .- 1527-3288. ; 34:6, s. 386-92
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Journal article (peer-reviewed)abstract
- PURPOSE: This study describes the quality of life (QOL) and uncertainty in patients who have an implantable cardioverter defibrillator (ICD) and predicts QOL at long-term follow-up. METHODS: Long-term follow-up was defined as 6.9 years +/- 1 year (range 4.11-8.7 years). QOL was measured with the Quality of Life Index, and uncertainty was measured with the Mishel Uncertainty in Illness Scale. RESULTS: The overall QOL and health/functioning were unchanged over time. QOL in the socioeconomic (P = .002) and psychologic/spiritual domains (P = .012) decreased in the first year. From baseline to long-term follow-up, the QOL in the family domain (P = .011) and uncertainty (P = .002) decreased. Uncertainty was a predictor of low QOL. CONCLUSION: QOL was reasonably good 6.9 years post-ICD implantation. Patients felt less uncertain once they had passed the first year of their illness.
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4. |
- Flemme, Inger, et al.
(author)
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Quality of life in relation to ICD shocks and uncertainty in patients living with an ICD : a 5-year old follow-up
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Other publication (other academic/artistic)abstract
- Aim: To describe quality of life (QoL) in relation to ICD (implantable cardioverter defibrillator) shocks and uncertainty in patients living with an ICD and to identify QoL predictors over a 5-year period.Methods: The Mishel Uncertainty in Illness Scale and Quality of Life Index were used for 35 patients. Higher scores indicate higher uncertainty and QoL.Results: From baseline to year 1, QoL overall (p = 0.033) and in the socioeconomic domain (p = 0.006) decreased. From year 1 to 5, QoL in the socioeconomic domain increased (p = 0.027) but decreased in the family domain (p = 0.039) as did uncertainty (p = 0.009). From baseline to year 5, uncertainty (p = 0.009) and QoL in the family domain decreased (p = <0.001). Patients reporting few ICD shocks were less troubled over time, thus uncertainty is a predictor of decreased QoL.Conclusion: ICD-patients felt better at year 5 than year 1. QoL was reasonably good 5 years post-implant, and patients felt more certain and perceived the ICD as a lifesaver.
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5. |
- Flemme, Inger, 1947-, et al.
(author)
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Quality of life related to shocks in ICD-recipients : a 5-year follow-up
- 2006
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In: 6th Annual Spring Meeting of the Working Group on Cardiovascular Nursing of the European Society of Cardiology and the Spring Meeting of the Norwegian National Society of Cardiovascular Nurses Bergen, Norway 5–6 May 2006. - London : Sage Publications. ; , s. S20-S20
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Conference paper (peer-reviewed)abstract
- Purpose: The purpose of this study was to describe QoL in relation to shocks and uncertainty in ICD-recipients and to identify predictors of QoL over a 5-year period. Methods: The design was prospective and longitudinal. Thirty-five patients who had lived with the ICD for at least five years had taken part in the study. All recipients had received their ICD as a form of secondary prevention. The questionnaires Mishel Uncertainty in Illness Scale – community version (MUIS-C), Quality of Life Index – cardiac version (QLI-CV) were completed on three occasions: before implantation, at year 1 and at year 5 after implantation. Self-reported number of shocks between the implantation and year 1 and between year 1 and year 5 were described. Data were analyzed by descriptive as well as analytical statistics. Results: In general, QoL was lower at year 1 than before implantation (p = 0.033). A decrease in the socio-economic domain was observed at year 1 (p = 0.006) but improved again at year 5 (p = 0.027) although it remained below the value before implantation. ICD recipient’s satisfaction with the family domain decreased from the time before ICD implantation (p = < 0.001) and from year 1 (p = 0.039) to year 5 after implantation. A decrease in overall uncertainty was observed at year 5 in relation to year 1 (p = 0.009). The longer the ICD recipient had lived with the device, the greater the risk of receiving a shock. However, ICD recipients who received shocks reported being less troubled by them over time. Uncertainty was identified as a predictor of low QoL. Conclusion: The recipients reported a higher level of QoL at year 5 than at year 1. QoL was reasonably good 5 years after implantation and the ICD recipient felt more secure and perceived their ICD as a lifesaver.
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6. |
- Flemme, Inger, et al.
(author)
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Quality of profile 1 and 5 years after ICD implantation
- 2004
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In: European Journal of Cardiovascular Nursing. - Amsterdam : Elsevier. - 1873-1953.
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Conference paper (peer-reviewed)abstract
- Aim: Treatment with implantable cardioverter defibrillators (ICDs) increases survival in patients suffering from ventricular tachyarrhythmias. The physiologic effects of having an ICD implanted are well-known but there is still limited knowledge about quality of life (QoL), especially in a long-term perspective. Therefore, the aim of this prospective, follow-up study was to describe and compare uncertainty and QoL at year 1 and year 5 after implantation in patients living with an ICD.Methods: The Mishel Uncertainty in Illness Scale-community version (MUIS-C) and Quality of Life Index-cardiac version (QLI) was used for 35 patients, living with an ICD in average 6 years 9 months. Higher scores indicate higher uncertainty and QoL.Results: An improvement in uncertainty was found at year 5 compared to year 1 (p=0.009), and at year 5 compared to baseline (p = 0.009). Overall QoL decreased at year 1 compared to baseline (p = 0.033). QoL in the socioeconomic domain decreased at year 1 compared to baseline (p = 0.006), and increased at year 5 compared to year 1 (p=0.027). QoL in the family domain decreased at year 5 compared to year 1 (p=0.039), and at year 5 compared to baseline (p=<0.001).Conclusion: Patients with ICD feel better at year 5 than at year 1. The QoL is reasonable good 5 years after implant once they have passed the first years and adapted to lifestyle changes, and patients are more certain and perceive the ICD as a parachute of life.
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7. |
- Hansson, Klas, 1944-, et al.
(author)
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Bakom bilderna : Biskopsporträtt i Strängnäs
- 2019. - 1
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Book (pop. science, debate, etc.)abstract
- Sedan reformationstiden finns en serie porträtt av Strängnäs stifts biskopar. De flesta hänger i domkapitelshuset, ett par i biskopsgården och de är inte lätta att få se. Men i denna bok visas de alla, från Petrus Jonæ till Hans-Erik Nordin. Vilka var då dessa män bakom bilderna? Alla biskopar sedan reformationen ges i denna bok en presentation; deras bakgrund, inriktning och biskopsgärning skildras. I en övergripande artikel sätts denna porträttkonst också in i sitt sammanhang. Stav, biskopsmössa och kors är tre av biskoparnas insignier. Strängnäsbiskoparnas kåpor, stavar och biskopsringar liksom biskopsstolen i domkyrkan skildras i text och bild, allt från biskop Rogges medeltida kåpa till dagens enkla resekåpor. Bakom bilderna har utarbetats inom Strängnäs stifts herdaminneskommitté och är författad av professor Ingun Montgomery, teol. dr. Jarl Jergmar, teol. dr. Fredrik Santell, prosten Karin Karlberg, fil. dr. Margareta Nisser Dalman och docent Klas Hansson, som också varit bokens redaktör.
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8. |
- Nisser Dalman, Margareta, 1957-
(author)
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Antiken som ideal : Det antikiserande inredningsmåleriet och dess sociala funktioner i högreståndsmiljöer i Dalarna och Gästrikland 1791-1818
- 2006
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Doctoral thesis (other academic/artistic)abstract
- This thesis focuses on classical style wall painting in the late 18th and early 19th centuries. The study specifically involves the governor's official residence in Falun and nine manor houses in the Swedish provinces of Dalarna and Gästrikland, all of which were decorated in the classical style by local artist Johan Nils Asplind between 1791 and 1818. The patrons were early industrialists; all but one were ironworks owners. The main purpose of the thesis is to describe and analyse the classical style ornamentation and its social functions in the above-mentioned buildings. The thesis comprises four main chapters, the first of which briefly deals with the origins and development of 18th century classical style decorative wall painting in Sweden, its influences, and its ideals. The next chapter describes and analyses the Governor’s official residence in Falun in terms of its historical furnishings and decorated interiors. The third of the main chapters describes and analyses the classical style wall painting and its social functions within the nine manor houses. The last of the main chapters analyses the art of Louis Masreliez, in particular the studies created during his twelve-year-long stay in Italy in the 1770s and 1780s. The analysis arrives at a new interpretation of Masreliez’s extensive collection of Italian studies. Contrary to previous research, the thesis claims that the studies are the work of a history painter, not a decorative painter. This allows for a new understanding of the origins of the artist’s classical style interiors, where the use of ornamental engravings is emphasized as a complement to the many studies of the human body. Together with the earlier chapters, this interpretation also results in a less static understanding of the use of models, and the thesis examines them in a more multifaceted way than hitherto has been the case in art history.
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10. |
- Nisser-Dalman, Margareta
(author)
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Drömmar på hemmaplan
- 2004
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In: Drömmen om Italien. - : Nationalmuseum, Stockholm. - 9171007067 ; , s. 152-
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Book chapter (pop. science, debate, etc.)
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