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Träfflista för sökning "WFRF:(Flink M) "

Search: WFRF:(Flink M)

  • Result 1-10 of 53
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  • Frantz, Laurent A. F., et al. (author)
  • Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe
  • 2019
  • In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 116:35, s. 17231-17238
  • Journal article (peer-reviewed)abstract
    • Archaeological evidence indicates that pig domestication had begun by similar to 10,500 y before the present ( BP) in the Near East, and mitochondrial DNA ( mtDNA) suggests that pigs arrived in Europe alongside farmers similar to 8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wild boars. This turnover could be accounted for by substantial gene flow from local European wild boars, although it is also possible that European wild boars were domesticated independently without any genetic contribution from the Near East. To test these hypotheses, we obtained mtDNA sequences from 2,099 modern and ancient pig samples and 63 nuclear ancient genomes from Near Eastern and European pigs. Our analyses revealed that European domestic pigs dating from 7,100 to 6,000 y BP possessed both Near Eastern and European nuclear ancestry, while later pigs possessed no more than 4% Near Eastern ancestry, indicating that gene flow from European wild boars resulted in a near-complete disappearance of Near East ancestry. In addition, we demonstrate that a variant at a locus encoding black coat color likely originated in the Near East and persisted in European pigs. Altogether, our results indicate that while pigs were not independently domesticated in Europe, the vast majority of human-mediated selection over the past 5,000 y focused on the genomic fraction derived from the European wild boars, and not on the fraction that was selected by early Neolithic farmers over the first 2,500 y of the domestication process.
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  • Bergström, Anders, et al. (author)
  • Grey wolf genomic history reveals a dual ancestry of dogs
  • 2022
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 607:7918, s. 313-320
  • Journal article (peer-reviewed)abstract
    • The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canis familiaris) lived. Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT88 40,000–30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, we also found that dogs in the Near East and Africa derive up to half of their ancestry from a distinct population related to modern southwest Eurasian wolves, reflecting either an independent domestication process or admixture from local wolves. None of the analysed ancient wolf genomes is a direct match for either of these dog ancestries, meaning that the exact progenitor populations remain to be located.
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  • Result 1-10 of 53
Type of publication
journal article (37)
conference paper (10)
other publication (5)
research review (1)
Type of content
peer-reviewed (37)
other academic/artistic (15)
pop. science, debate, etc. (1)
Author/Editor
Flink, M (27)
Ytterberg, C (13)
Lindblom, S (11)
von Koch, L (9)
Olsson, M. (5)
Ekholm, Elin, 1981- (5)
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Hultman, Lars (4)
Flink, Ida, 1980- (4)
Ohlen, G (4)
Schoonhoven, L. (4)
Vernooij-Dassen, M. (4)
Ter Kuile, Moniek M. (4)
Flink, Roland (3)
Karlsson, L (3)
Koch, L. (3)
Larsson, T (3)
Ekstedt, M (3)
Hultman, L (3)
Hansagi, H (3)
Flink, Axel (3)
Gilbert, M. Thomas P ... (3)
Girdland-Flink, Linu ... (3)
Johnson, JK (3)
Elf, M (3)
Sjölen, J. (3)
Lundqvist, M (2)
Linton, Steven J., 1 ... (2)
Kierkegaard, M (2)
Larson, Greger (2)
Linderholm, Anna (2)
Laska, AC (2)
Laska, A (2)
Götherström, Anders, ... (2)
Elf, Marie, 1962- (2)
Lebrasseur, Ophelie (2)
Gopalakrishnan, Shya ... (2)
Haile, James (2)
Wickstrom, R (2)
Carlsson, AC (2)
Ågren, Johan, 1966- (2)
Pinhasi, Ron (2)
Flink, Ida K., 1980- (2)
Storå, Jan, 1963- (2)
Benecke, Norbert (2)
Skoglund, Pontus (2)
Johansson, M.P. (2)
Gottberg, K (2)
Engman, Linnea (2)
Engman, Linnea, 1987 ... (2)
Tuijnman-Raasveld, C ... (2)
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University
Karolinska Institutet (33)
Uppsala University (9)
Örebro University (7)
Linköping University (7)
Stockholm University (3)
Linnaeus University (3)
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Royal Institute of Technology (2)
Karlstad University (2)
Högskolan Dalarna (2)
Malmö University (1)
Swedish Museum of Natural History (1)
Marie Cederschiöld högskola (1)
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Language
English (50)
Undefined language (2)
Swedish (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (9)
Natural sciences (7)
Social Sciences (6)
Engineering and Technology (1)
Humanities (1)

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