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- Arvidsson, Barbro, et al.
(author)
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Nurses' various ways of conceiving their learning process as doctoral students: A phenomenographic study
- 2013
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In: Nurse Education in Practice. - Kidlington : Elsevier BV. - 1471-5953 .- 1873-5223. ; 13:1, s. 53-57
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Journal article (peer-reviewed)abstract
- Aim: The aim was to describe variations in how doctoral students conceive their learning process to become researchers in the light of their professional background as nurses. Background: Nursing research is an emerging discipline and the number of nurses who acquire a doctor's degree is increasing. Method: The study had a descriptive, qualitative design with a phenomenographic approach and was carried out by means of 20 interviews. Results: Three different description categories emerged: (1) A learning process that provides a synthesis of different parts of the research process aimed at developing preparedness for action within the nursing profession. (2) A learning process where practical problems are integrated with and problematised in relation to scientific theories. (3) A learning process involving the transformation from nurse to researcher. Conclusions: The description categories revealed that the focus was on solving problems that occur in health care and synthesising them by means of research tools. Furthermore, the doctoral students explored different ways of understanding and developing their awareness of the nature of research. Focus was also on the nursing profession and practice and a shift towards the role of a researcher was evident. © 2012 Elsevier Ltd.
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- Bonfiglio, Ferdinando, et al.
(author)
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GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome
- 2021
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In: Cell Genomics. - Cambridge, MA, United States : Elsevier. - 2666-979X. ; 1:3
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Journal article (peer-reviewed)abstract
- Gut dysmotility is associated with constipation, diarrhea, and functional gastrointestinal disorders like irritable bowel syndrome (IBS), although its molecular underpinnings are poorly characterized. We studied stool frequency (defined by the number of bowel movements per day, based on questionnaire data) as a proxy for gut motility in a GWAS meta-analysis including 167,875 individuals from UK Biobank and four smaller population-based cohorts. We identify 14 loci associated with stool frequency (p ≤ 5.0 × 10-8). Gene set and pathway analyses detected enrichment for genes involved in neurotransmitter/neuropeptide signaling and preferentially expressed in enteric motor neurons controlling peristalsis. PheWAS identified pleiotropic associations with dysmotility syndromes and the response to their pharmacological treatment. The genetic architecture of stool frequency correlates with that of IBS, and UK Biobank participants from the top 1% of stool frequency polygenic score distribution were associated with 5× higher risk of IBS with diarrhea. These findings pave the way for the identification of actionable pathological mechanisms in IBS and the dysmotility syndromes.
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| 5. |
- Franke, Anita, et al.
(author)
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Högskolepedagogisk handledning : Erfarenheter av pedagogisk förnyelse vid Högskolan i Halmstad
- 2007
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Book (other academic/artistic)abstract
- Upprinnelsen till denna arbetsrapport är erfarenheter av ett pedagogiskt utvecklingsarbete om högskolepedagogisk handledning, finansierat av Högskoleverket, Rådet för högre utbildning. Projektet planerades och genomfördes i ett konsortium under 2003 samt avrapporterades i april 2004. Konsortiet bestod av Chalmers Lindholmen, Göteborg; Blekinge Tekniska Högskola, Karlskrona och Högskolan i Halmstad, Halmstad. Projektledare var Anita Franke, Institutionen för pedagogik och didaktik, Göteborgs universitet. Övriga projektmedarbetare var: Elsie Anderberg, Institutionen för pedagogik och didaktik, Göteborgs universitet, Erling Fjeldstad, CKK, Chalmers Tekniska Högskola, Helene Ivarsson, Christer Alvegård och Jörgen Andersson, Blekinge Tekniska Högskola samt Barbro Arvidsson och Bertil Gustafsson, Sektionen för hälsa och samhälle, Högskolan i Halmstad.Projektets idé om pedagogisk utveckling var att utveckla handledningskompetens hos lärare inom högskolan. Avsikten var att hos kursdeltagarna försöka åstadkomma en medvetenhet om lärande och lärprocesser i arbetet med pedagogisk handledning bland studerande och doktorander.Denna rapport är ett resultat av ett fortsatt samarbete kring frågor om högskolepedagogisk handledning mellan Anita Franke och Barbro Arvidsson. Medverkar i rapporten gör också Bertil Gustafsson. Vår avsikt är att visa på betydelsen av att högskolelärares kompetens i arbetet med handledning och undervisning grundas i pedagogiska teorier. Mot denna bakgrund beskrivs, analyseras, och reflekteras erfarenheter och exempel från det pedagogiska utvecklingsarbetets planering och genomförande vid Högskolan i Halmstad. Rapporten är tänkt att användas i arbetet med högskolepedagogisk utbildning och i pedagogiskt utvecklingsarbete.
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| 8. |
- Franke, Anita, 1946, et al.
(author)
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Research supervisors' different ways of experiencing supervision of doctoral students
- 2011
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In: STUDIES IN HIGHER EDUCATION. - Oxford : Carfax Publishing. - 0307-5079 .- 1470-174X. ; 36:1, s. 7-19
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Journal article (peer-reviewed)abstract
- Research supervisors’ different ways of experiencing their supervision of doctoral students are analysed in terms of the students’ questions and problems as they relate to the supervisor’s research, and what consequences this connection, or non‐connection, to the supervisor’s research has for supervision and the role of supervisor. Thirty supervisors of doctoral students at different faculties at a university in Sweden were interviewed. The results illustrate two supervision structures, called research practice‐oriented and research relation‐oriented supervision. The principal differences between these two ways of structuring supervision consist of whether the supervisor and the doctoral student participate in a common research practice and share objects of research with the same or a related research approach, or whether the doctoral student’s research problems and research objects lack a clear connection with the supervisor’s research.
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| 10. |
- Hibar, Derrek P., et al.
(author)
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Novel genetic loci associated with hippocampal volume
- 2017
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In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8
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Journal article (peer-reviewed)abstract
- The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (r(g) = -0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.
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