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- Ahrenby, Hanna, 1978-
(författare)
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Värdegrundsarbete i bildundervisning : en studie om iscensättning av policy i grundskolans senare år
- 2021
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The overall purpose of this thesis is to describe and discuss preconditions for the enactment and the construction of fundamental values in art education in secondary school. The study is based on ethnographic methods, including classroom observations, video recordings and interviews with art teachers and pupils. Three art teachers and 36 pupils in grade eight and nine (age 14-16) have participated in the study. The schools are located in areas of different socio-economic status. Besides interviews, the empirical material consists of observation notes, video and sound recordings, documents and photographs from the observed lessons. In total, 27 lessons were observed and recorded, 20 interviews with teachers and seven interviews with pupils were conducted. The empirical material is analysed with a combination of policy enactment theory (Ball et al. 2012) and concepts form Bernstein (2000, 2003) and Bakhtin (1981, 1986).The analysis reveals that the conditions for policy enactment are created by several factors that interact. It is impossible to designate a single factor to explain why the enacted curriculum turns out the way it does. The contextual dimensions, such as material context, situated context, professional culture and external context (Ball et al. 2012), constitute a complex and unique contextual mix in every school. Together with existing subject traditions and teaching practices in art education, the unique contextual mix creates the conditions for enacting the fundamental values in art education.The art subject carries a tradition of image-making that pushes more theoretical syllabus content,such as image analysis, aside. The situated context influences the professional culture and, therefore,they function as a lens for selecting and translating the curriculum. Regardless of teachers' intentionsto enact the fundamental values in art education, the external context can create obstacles. The goal and result management of school leads to a focus on measurable subject knowledge and drive awayother curriculum parts such as the fundamental values, making it challenging to work with fundamental values in Art education.In conclusion, there are no prerequisites for realising the intentions of the fundamental values as expressed in the curriculum. Despite this, the fundamental values have a given place in Art education. Although, it is not always expressed verbally; instead, it is image-borne.
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| 2. |
- Askman, Sandra, et al.
(författare)
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Decreased neutrophil function in newly diagnosed multiple myeloma patients is restored with lenalidomide therapy
- 2024
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Ingår i: EUROPEAN JOURNAL OF HAEMATOLOGY. - 0902-4441 .- 1600-0609.
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Tidskriftsartikel (refereegranskat)abstract
- ObjectivesBacterial infections are common and a major cause of morbidity and mortality in multiple myeloma (MM). We have investigated the function of polymorphonuclear leukocyte (PMN), the immune system's first line of defense against bacteria, in peripheral blood (PB) and bone marrow (BM) samples from patients with newly diagnosed MM (NDMM), smoldering MM (SMM), monoclonal gammopathy of undetermined significance (MGUS) and healthy controls.MethodsPhagocytosis and oxidative burst in PMN cells from patients and healthy donors were investigated using PhagoTest and PhagoBurst assay.ResultsPMN from NDMM, SMM, and MGUS patients had reduced phagocytosis and oxidative burst ability compared with healthy controls. The dysfunction was most prominent in BM samples from MM, SMM, and MGUS patients. Importantly the reduced phagocytosis in MM patients was restored in patients on lenalidomide therapy. Consistently the ability of Escherichia coli stimulated oxidative burst in BM was reduced for the MM, SMM, and MGUS cohort in contrast to the healthy controls and the patients on lenalidomide treatment.ConclusionOur results show that MM patients have neutrophil dysfunction that could contribute to susceptibility for bacterial infections and that lenalidomide therapy was associated with restored PMN function.
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| 3. |
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| 4. |
- Bengtsson, Anders, et al.
(författare)
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Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus
- 2014
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Ingår i: Arthritis Research and Therapy. - : Springer Science and Business Media LLC. - 1478-6362 .- 1478-6354. ; 16:3
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Polymorphonuclear leukocytes (PMN) are main effector cells in the acute immune response. While the specific role of PMN in systemic lupus erythematosus (SLE) and autoimmunity is still unclear, their importance in chronic inflammation is gaining more attention. Here we investigate aspects of function, bone marrow release and activation of PMN in patients with SLE. Methods: The following PMN functions and subsets were evaluated using flow cytometry; (a) production of reactive oxygen species (ROS) after ex vivo stimulation with phorbol 12-myristate 13-acetate (PMA) or Escherichia coli (E. coli); (b) capacity to phagocytose antibody-coated necrotic cell material; (c) PMN recently released from bone marrow, defined as percentage of CD10(-)D16(low) in peripheral blood, and (d) PMN activation markers; CD11b, CD62L and C5aR. Results: SLE patients (n = 92) showed lower ROS production compared with healthy controls (n = 38) after activation ex vivo. The ROS production was not associated with corticosteroid dose or other immunotherapies. PMA induced ROS production was significantly reduced in patients with severe disease. In contrast, neither ROS levels after E. coli activation, nor the capacity to phagocytose were associated with disease severity. This suggests that decreased ROS production after PMA activation is a sign of changed PMN behaviour rather than generally impaired functions. The CD10(-)CD16(low) phenotype constitute 2% of PMN in peripheral blood of SLE patients compared with 6.4% in controls, indicating a decreased release of PMN from the bone marrow in SLE. A decreased expression of C5aR on PMN was observed in SLE patients, pointing towards in vivo activation. Conclusions: Our results indicate that PMN from SLE patients have altered function, are partly activated and are released abnormally from bone marrow. The association between low ROS formation in PMN and disease severity is consistent with findings in other autoimmune diseases and might be considered as a risk factor.
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| 5. |
- Berndes, Göran, 1966, et al.
(författare)
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Expanding sugarcane ethanol production in Brazil - Socioeconomic and climate effects of expanding sugarcane ethanol production in the Pontal do Paranapanema region (State of São Paulo, Brazil)
- 2007
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Ingår i: Proceedings of the 15th European Biomass Conference & Exhibition - From research to market Deployment, Berlin, Germany, 7-11 May 2007.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- This paper presents results from a study of socioeconomic and climate effects connected to a sugarcane expansion scenario in the Pontal do Paranapanema region, São Paulo state, Brazil. Sugarcane production is expected to grow in the São Paulo state. Pontal do Paranapanema is the only region in the state where a large scale sugarcane expansion can take place and there is a concern that without guidelines the expansion might affect income growth in a negative way. A scenario where the settlers in the region gain from the sugarcane expansion was modelled. The models showed that it is possible to introduce sugarcane in the region with positive effects both on income growth and greenhouse gas emissions.
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| 6. |
- Byström, Erik, 1980, et al.
(författare)
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En e-resurs vara eller inte vara. En kvalitativ metod för utvärdering av tidskrifter och databaser.
- 2017
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Ingår i: Förvärv i en föränderlig tid: Nationell konferens om förvärv och samlingsuppbyggnad. Kungliga biblioteket, 1 juni 2017.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Under 2015 och 2016 testade Göteborgs universitetsbibliotek att använda mellansidor som en metod för att utvärdera den kvalitativa användningen av en e-tidskrift eller databas. I Postern presenteras tillvägagångssätt och resultat.
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| 7. |
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| 8. |
- Earle, Anton, et al.
(författare)
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Transboundary water management and the climate change debate
- 2015
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Climate change has an impact on the ability of transboundary water management institutions to deliver on their respective mandates. The starting point for this book is that actors within transboundary water management institutions develop responses to the climate change debate, as distinct from the physical phenomenon of climate change. Actors respond to this debate broadly in three distinct ways – adapt, resist (as in avoiding the issue) and subvert (as in using the debate to fulfil their own agenda). The book charts approaches which have been taken over the past two decades to promote more effective water management institutions, covering issues of conflict, cooperation, power and law.
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| 9. |
- Edvardsson, Mats, et al.
(författare)
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Retorik och litteratur
- 1991
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Ingår i: Samlaren. - Uppsala. - 0348-6133 .- 2002-3871. ; 112, s. 73-80
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Tidskriftsartikel (refereegranskat)
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| 10. |
- Ekman, Stina, et al.
(författare)
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Osteochondrosis in the central and third tarsal bones of young horses
- 2024
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Ingår i: Veterinary Pathology. - 0300-9858 .- 1544-2217. ; 61, s. 74 - 87
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Tidskriftsartikel (refereegranskat)abstract
- Recently, the central and third tarsal bones of 23 equine fetuses and foals were examined using micro-computed tomography. Radiological changes, including incomplete ossification and focal ossification defects interpreted as osteochondrosis, were detected in 16 of 23 cases. The geometry of the osteochondrosis defects suggested they were the result of vascular failure, but this requires histological confirmation. The study aim was to examine central and third tarsal bones from the 16 cases and to describe the tissues present, cartilage canals, and lesions, including suspected osteochondrosis lesions. Cases included 9 males and 7 females from 0 to 150 days of age, comprising 11 Icelandic horses, 2 standardbred horses, 2 warmblood riding horses, and 1 coldblooded trotting horse. Until 4 days of age, all aspects of the bones were covered by growth cartilage, but from 105 days, the dorsal and plantar aspects were covered by fibrous tissue undergoing intramembranous ossification. Cartilage canal vessels gradually decreased but were present in most cases up to 122 days and were absent in the next available case at 150 days. Radiological osteochondrosis defects were confirmed in histological sections from 3 cases and consisted of necrotic vessels surrounded by ischemic chondronecrosis (articular osteochondrosis) and areas of retained, morphologically viable hypertrophic chondrocytes (physeal osteochondrosis). The central and third tarsal bones formed by both endochondral and intramembranous ossification. The blood supply to the growth cartilage of the central and third tarsal bones regressed between 122 and 150 days of age. Radiological osteochondrosis defects represented vascular failure, with chondrocyte necrosis and retention, or a combination of articular and physeal osteochondrosis.
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