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- Henriksson, Anders E., et al.
(author)
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Identification of Potential Plasma Biomarkers for Abdominal Aortic Aneurysm Using Tandem Mass Tag Quantitative Proteomics
- 2018
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In: Proteomes. - : MDPI AG. - 2227-7382. ; 6:4
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Journal article (peer-reviewed)abstract
- Plasma biomarkers that identify abdominal aortic aneurysm (AAA) rupture risk would greatly assist in stratifying patients with small aneurysms. Identification of such biomarkers has hitherto been unsuccessful over a range of studies using different methods. The present study used an alternative proteomic approach to find new, potential plasma AAA biomarker candidates. Pre-fractionated plasma samples from twelve patients with AAA and eight matched controls without aneurysm were analyzed by mass spectrometry applying a tandem mass tag (TMT) technique. Eight proteins were differentially regulated in patients compared to controls, including decreased levels of the enzyme bleomycin hydrolase. The down-regulation of this enzyme was confirmed in an extended validation study using an enzyme-linked immunosorbent assay (ELISA). The TMT-based proteomic approach thus identified novel potential plasma biomarkers for AAA.
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- Henriksson, Carina
(author)
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Curriculum in Abundance – A Phenomenological Reading
- 2009
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In: Journal of the American Association for the Advancement of Curriculum Studies. - : the American Association for the Advancement of Curriculum Studies. ; 5:2, s. 1-19
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Journal article (peer-reviewed)
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- Henriksson, Carina
(author)
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Editorial
- 2007
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Other publication (pop. science, debate, etc.)
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9. |
- Henriksson, Carina
(author)
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Editorial
- 2008
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In: Phenomenology & Practice. - 1913-4711. ; 2:1, s. 1-3
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Journal article (other academic/artistic)
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