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- 2019
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Journal article (peer-reviewed)
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- Su, Zhan, et al.
(author)
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Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.
- 2012
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 44:10
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Journal article (peer-reviewed)abstract
- Barrett's esophagus is an increasingly common disease that is strongly associated with reflux of stomach acid and usually a hiatus hernia, and it strongly predisposes to esophageal adenocarcinoma (EAC), a tumor with a very poor prognosis. We report the first genome-wide association study on Barrett's esophagus, comprising 1,852 UK cases and 5,172 UK controls in the discovery stage and 5,986 cases and 12,825 controls in the replication stage. Variants at two loci were associated with disease risk: chromosome 6p21, rs9257809 (Pcombined=4.09×10(-9); odds ratio (OR)=1.21, 95% confidence interval (CI)=1.13-1.28), within the major histocompatibility complex locus, and chromosome 16q24, rs9936833 (Pcombined=2.74×10(-10); OR=1.14, 95% CI=1.10-1.19), for which the closest protein-coding gene is FOXF1, which is implicated in esophageal development and structure. We found evidence that many common variants of small effect contribute to genetic susceptibility to Barrett's esophagus and that SNP alleles predisposing to obesity also increase risk for Barrett's esophagus.
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- May, Sally K., et al.
(author)
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Early Australian Anthropomorphs : Jabiluka's Dynamic Figure Rock Paintings
- 2018
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In: Cambridge Archaeological Journal. - : Cambridge University Press. - 0959-7743 .- 1474-0540. ; 28:1, s. 67-83
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Journal article (peer-reviewed)abstract
- Early depictions of anthropomorphs in rock art provide unique insights into life during the deep past. This includes human engagements with the environment, socio-cultural practices , gender and uses of material culture. In Australia, the Dynamic Figure rock paintings of Arnhem Land are recognized as the earliest style in the region where humans are explicitly depicted. Important questions, such as the nature and signicance of body adornment in rock art and society, can be explored, given the detailed nature of the human gurative art and the sheer number of scenes depicted. In this paper, we make a case for Dynamic Figure rock art having some of the earliest and most extensive depictions of complex an-thropomorph scenes found anywhere in the world.
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- May, Sally K., et al.
(author)
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New Insights into the Rock Art of Anbangbang Gallery, Kakadu National Park
- 2020
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In: Journal of field archaeology. - : Taylor & Francis Group. - 0093-4690 .- 2042-4582. ; 45:2, s. 120-134
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Journal article (peer-reviewed)abstract
- This paper presents findings from a recent study of the Anbangbang Gallery in the Burrungkuy (Nourlangie) site complex of Kakadu National Park, Australia. Using new technologies alongside established methods for rock art documentation, we discuss the complexity and uniqueness of Anbangbang Gallery as an icon of Australian rock art. We have taken a comprehensive approach to our investigations, deliberately linking new technologies and scientific analysis with other archaeological and anthropological research methods. In particular, using evidence from a detailed site recording, oral histories, and pXRF analysis, we explore aspects of the site chronology, the nature of painting activity, and the retouching and repainting of earlier imagery. The findings force us to rethink the existing interpretative narrative for Anbangbang Gallery, the motivations behind previously held beliefs relating to recent rock art, and the implications this has had for ongoing conservation work in the region.
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- May, Sally K., et al.
(author)
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‘This is my father’s painting’ : A first-hand account of the creation of the most iconic rock art in Kakadu National Park
- 2019
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In: Rock Art Research. - : Archaeological Publications, Australia. - 0813-0426. ; 36:2, s. 199-213
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Journal article (peer-reviewed)abstract
- The Anbangbang Gallery in the Burrungkuy area of Kakadu National Park includes some of the most iconic rock art imagery from Australia. Visited and enjoyed by tens of thousands of visitors every year it stands as a testament to Aboriginal culture and provides a glimpse into the remarkable rock art traditions of this region. Yet, most visitors are surprised to discover that rock art was still being produced at this site in the 1960s. In this paper, we explore the most recent rock art created at the Anbangbang Gallery. Most importantly, we present new evidence from a first-hand account of the paintings being created in 1963/64 and discuss the implications of these new insights for our understanding of the practice, the artists, and the social context of rock art in northern Australia.
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