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- Chatzidiamantis, N. D., et al.
(författare)
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Inverse Gaussian Modeling of Turbulence-Induced Fading in Free-Space Optical Systems
- 2011
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Ingår i: Journal of Lightwave Technology. - : Institute of Electrical and Electronics Engineers (IEEE). - 0733-8724 .- 1558-2213. ; 29:10, s. 1590-1596
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Tidskriftsartikel (refereegranskat)abstract
- We propose the inverse Gaussian distribution, as a less complex alternative to the classical log-normal model, to describe turbulence-induced fading in free-space optical (FSO) systems operating in weak turbulence conditions and/or in the presence of aperture averaging effects. By conducting goodness of fit tests, we define the range of values of the scintillation index for various multiple-input multiple-output (MIMO) FSO configurations, where the two distributions approximate each other with a certain significance level. Furthermore, the bit error rate performance of two typical MIMO FSO systems is investigated over the new turbulence model; an intensity-modulation/direct detection MIMO FSO system with Q-ary pulse position modulation that employs repetition coding at the transmitter and equal gain combining at the receiver, and a heterodyne MIMO FSO system with differential phase-shift keying and maximal ratio combining at the receiver. Finally, numerical results are presented that validate the theoretical analysis and provide useful insights into the implications of the model parameters on the overall system performance.
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- Grasselli, Giacomo, et al.
(författare)
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ESICM guidelines on acute respiratory distress syndrome : definition, phenotyping and respiratory support strategies
- 2023
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Ingår i: Intensive Care Medicine. - : Springer Nature. - 0342-4642 .- 1432-1238. ; 49, s. 727-759
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Tidskriftsartikel (refereegranskat)abstract
- The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients' representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical practice and identifies the areas of future research.
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- Yoo, S.K., et al.
(författare)
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The K - μ / inverse gamma fading model
- 2015
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Ingår i: IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, PIMRC. - 9781467367820 ; 2015-December, s. 425-429
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Konferensbidrag (refereegranskat)abstract
- © 2015 IEEE. Statistical distributions have been extensively used in modeling fading effects in conventional and modern wireless communications. In the present work, we propose a novel κ - μ composite shadowed fading model, which is based on the valid assumption that the mean signal power follows the inverse gamma distribution instead of the lognormal or commonly used gamma distributions. This distribution has a simple relationship with the gamma distribution, but most importantly, its semi heavy-tailed characteristics constitute it suitable for applications relating to modeling of shadowed fading. Furthermore, the derived probability density function of the κ - μ / inverse gamma composite distribution admits a rather simple algebraic representation that renders it convenient to handle both analytically and numerically. The validity and utility of this fading model are demonstrated by means of modeling the fading effects encountered in body centric communications channels, which have been known to be susceptible to the shadowing effect. To this end, extensive comparisons are provided between theoretical and respective real-time measurement results. It is shown that these comparisons exhibit accurate fitting of the new model for various measurement set ups that correspond to realistic communication scenarios.
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- Yoo, S.K., et al.
(författare)
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The η - μ / inverse gamma composite fading model
- 2015
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Ingår i: IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, PIMRC. - 2166-9570. - 9781467367820 ; 2015-December, s. 166-170
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Konferensbidrag (refereegranskat)abstract
- © 2015 IEEE. In this paper we propose a new composite fading model which assumes that the mean signal power of an η - μ signal envelope follows an inverse gamma distribution. The inverse gamma distribution has a simple relationship with the gamma distribution and can be used to model shadowed fading due to its semi heavy-tailed characteristics. To demonstrate the utility of the new η - μ / inverse gamma composite fading model, we investigate the characteristics of the shadowed fading behavior observed in body centric communications channels which are known to be susceptible to shadowing effects, particularly generated by the human body. It is shown that the η - μ / inverse gamma composite fading model provided an excellent fit to the measurement data. Moreover, using Kullback-Leibler divergence, the η - μ / inverse gamma composite fading model was found to provide a better fit to the measured data than the k - μ / inverse gamma composite fading model, for the communication scenarios considered here.
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6. |
- Akdis, M, et al.
(författare)
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Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
- 2004
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Ingår i: Journal of Experimental Medicine. - : Rockefeller University Press. - 0022-1007 .- 1540-9538. ; 199:11, s. 1567-1575
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Tidskriftsartikel (refereegranskat)abstract
- The mechanisms by which immune responses to nonpathogenic environmental antigens lead to either allergy or nonharmful immunity are unknown. Single allergen-specific T cells constitute a very small fraction of the whole CD4(+) T cell repertoire and can be isolated from the peripheral blood of humans according to their cytokine profile. Freshly purified interferon-gamma-, interleukin (IL)-4-, and IL-10-producing allergen-specific CD4(+) T cells display characteristics of T helper cell (Th)1-, Th2, and T regulatory (Tr)1-like cells, respectively. Tr1 cells consistently represent the dominant subset specific for common environmental allergens in healthy individuals; in contrast, there is a high frequency of allergen-specific IL-4-secreting T cells in allergic individuals. Tr1 cells use multiple suppressive mechanisms, IL-10 and TGF-beta as secreted cytokines, and cytotoxic T lymphocyte antigen 4 and programmed death 1 as surface molecules. Healthy and allergic individuals exhibit all three allergen-specific subsets in different proportions, indicating that a change in the dominant subset may lead to allergy development or recovery. Accordingly, blocking the suppressor activity of Tr1 cells or increasing Th2 cell frequency enhances allergen-specific Th2 cell activation ex vivo. These results indicate that the balance between allergen-specific Tr1 cells and Th2 cells may be decisive in the development of allergy.
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7. |
- Bao, J., et al.
(författare)
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Joint Multiuser Detection of Multidimensional Constellations over Fading Channels
- 2017
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Ingår i: IEEE Transactions on Communications. - : IEEE Press. - 0090-6778 .- 1558-0857. ; 65:1, s. 161-172
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Tidskriftsartikel (refereegranskat)abstract
- We investigate the error performance of multidimensional constellations in the multiple access and broadcast channels. More specifically, we provide closed-form expressions for the pairwise error probability (PEP) of the joint maximum likelihood detection, for multiuser signaling in the presence of additive white Gaussian noise and Rayleigh fading. Arbitrary numbers of users and multidimensional signal sets are assumed, while the provided formula for the PEP is a function of the dimension-wise distances of the multidimensional constellation. Furthermore, a useful upper bound on the average symbol error probability is also obtained through the union bound. The analysis is applied to the sparse code multiple access systems. The analytical results are validated successfully through simulations, and show their importance in the multidimensional constellation design.
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