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- Zhang, Shunming, et al.
(författare)
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Added sugar intake and its forms and sources in relation to risk of non-alcoholic fatty liver disease : results from the Tianjin Chronic Low-grade Systemic Inflammation and Health cohort study
- 2023
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Ingår i: British Journal of Nutrition. - 1475-2662. ; 129:12, s. 2094-2101
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Tidskriftsartikel (refereegranskat)abstract
- It has been suggested that added sugar intake is associated with non-alcoholic fatty liver disease (NAFLD). However, previous studies only focused on sugar-sweetened beverages; the evidence for associations with total added sugars and their sources is scarce. This study aimed to examine the associations of total added sugars, their physical forms (liquid vs. solid), and food sources with risk of NAFLD among adults in Tianjin, China. We used data from 15,538 participants, free of NAFLD, other liver diseases, cardiovascular disease, cancer, or diabetes at baseline (2013-2018 years). Added sugar intake was estimated from a validated 100-item food frequency questionnaire. NAFLD was diagnosed by ultrasonography after exclusion of other causes of liver diseases. Multivariable Cox proportional hazards models were fitted to calculate hazards ratios (HRs) and corresponding 95% confidence intervals (CIs) for NAFLD risk with added sugar intake. During a median follow-up of 4.2 years, 3,476 incident NAFLD cases were documented. After adjusting for age, sex, body mass index and its change from baseline to follow-up, lifestyle factors, personal and family medical history, and overall diet quality, the multivariable HRs (95% CIs) of NAFLD risk were 1.18 (1.06, 1.32) for total added sugars, 1.20 (1.08, 1.33) for liquid added sugars, and 0.96 (0.86, 1.07) for solid added sugars when comparing the highest quartiles of intake with the lowest quartiles of intake. In this prospective cohort of Chinese adults, higher intakes of total added sugars and liquid added sugars, but not solid added sugars, were associated with a higher risk of NAFLD.
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| 2. |
- Li, Zhixia, et al.
(författare)
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Calibrating VISSIM roundabout model using a critical gap and follow-up headway approach
- 2013
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Ingår i: Proceedings of the 16th International Conference Road Safety on Four Continents. - Linköping : Statens väg- och transportforskningsinstitut.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Roundabouts have been continuously constructed in the U.S. in recent years, as studies have shown their capability of reducing crash risk and severity when compared with signalized intersections. Despite of the safety benefits offered by roundabouts, operational efficiency is required be analyzed when considering building roundabouts. As a prevailing simulation platform for modeling roundabouts, VISSIM have been widely applied in practice to facilitate analyzing the operational performance of roundabouts. Considering that an essential prerequisite to preparing a VISSIM roundabout model is to calibrate the model by adjusting VISSIM parameters, comprehensive calibration guidance is of great importance to practitioners. Previous calibration research has conducted qualitative analysis to study the impact of VISSIM parameters on roundabout capacity. However, parameter values based on field data and quantitative calibration guidelines are more helpful to facilitate fast and accurate modeling of roundabouts. This paper addresses these important needs. Speed trajectories of free-flow entering vehicles were collected in the field using a radar sensor. Location, length, speed distribution, and deceleration rate parameters for the VISSIM Reduced Speed Areas (RSA) were determined through the analysis of the radar data. The impact of VISSIM parameters on critical gap and follow-up headway was quantitatively analyzed through sensitivity analysis of minimum gap for PR, speed distribution and deceleration rate for RSA, and additive and multiplicative settings for the Wiedemann 74 model. Numerical guidelines for calibrating VISSIM roundabout models were ultimately developed, and validated via a case study.
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