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- Törnqvist, Daniel, 1974-
(författare)
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När man talar om knark : drogdebatt i svensk dagspress 1970-1999
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis presents a study of the debate on drugs in the Swedish press from 1970 to 1999. Applying a social constructionist and critical discourse perspective, it aims to map out and analyze the discourse on drugs in a large number of Swedish newspapers. The main focus is on debate articles and editorials. The research questions are concerned with (1) how the drug problem has been articulated, and with (2) what the represen¬ta-tion¬al patterns found say about Swedish society, its social relations and social history on a higher level of abstraction. The practical analysis is oriented towards discerning (a) major themes, standpoints and controversies, (b) major views on people using drugs, and (c) major ideas about what should be done and how, within the drug discourse of Swedish media during three decades. Parts of the analyses are also devoted to finding out which actors have been influential in the debate on drugs, and what type of rhetoric has been employed.Results are presented in three chapters: one about the 1970s, one about the 1980s, and one about the 1990s. The drug problem is formulated, already during the 1970s, as a pressing and urgent problem in Swedish society. During the course of the two following decades, this fact is underlined more and more – even though an increasing amount of voices critical to this perspectives are raised towards the end of the 1990s. The threat is articulated during the 1970s as stemming from a faulty political system driving certain groups of people into helplessness drug abuse. During the 1980s and 1990s, however, impending liberalization of attitudes and legislation was increasingly constructed as the most imminent danger. The drug user was represented as a victim of social injustices during the seventies, but to an increasing extent – during the eighties and nineties – as belonging to certain youth groups who were perceived to be at risk of becoming drug abusers. When it comes to the measures prescribed, a steady development in the direction of increased repressiveness and tougher attitudes towards drugs and their users, is to be found over the course of the time period under study.The concluding discussion illustrates that the discourse on drugs is related to a number of other discourses to which it relates at various times, with various effects (a discourse of social critique, a legal discourse, a moral discourse, a discourse on youth and popular culture, and a discourse of Swedishness). The identified tendencies and discursive patterns are discussed in relation to the unique history of the temperance movement in Sweden, and analyzed with the help of John B. Thompson’s theory of media and ideology, Stanley Cohen’s theory on “folk devils and moral panics” and Kai T. Erikson’s idea about “boundary crises”. The main conclusion is that the drug debate is a vehicle through which such far reaching issues as those of morality, law and politics, national identity, the upbringing of youth and the future can be channeled.
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- Aleman, Soo, et al.
(författare)
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Health check-ups and family screening allow detection of hereditary hemochromatosis with less advanced liver fibrosis and survival comparable with the general population
- 2011
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Ingår i: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 0036-5521 .- 1502-7708. ; 46:9, s. 1118-1126
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Tidskriftsartikel (refereegranskat)abstract
- Objective. The information concerning the morbidity and mortality of hereditary hemochromatosis is based primarily on clinical cohorts of symptomatic patients. The major aim of this study was to analyze the long-term prognosis for Swedish patients with this condition, with respect to both clinical features and survival, in relation to the route by which the disease was detected. Patients and methods. 373 patients with hemochromatosis detected through routine health checkups (n = 153), family screening (n = 44), symptoms of arthralgia (n = 23), investigation of other diseases/symptoms (n = 108) or signs of liver disease (n = 45) were monitored for a mean period of 11.9 +/- 5.8 years. The degree of liver fibrosis and survival were analyzed. Results. Overall survival among these patients was not significantly different from that of a matched normal population. The patients diagnosed through health check-ups and family screening were detected at an earlier age and had the highest rate of survival. Liver biopsy at the time of diagnosis revealed cirrhosis in 9% of those detected through the health check-ups and 5% in the case of family screening, compared with 13% for the group with arthralgia, 17% for other diseases/symptoms and 42% for liver disease. Conclusion. Health check-ups and family screening allow detection of hereditary hemochromatosis at an earlier age and with less advanced liver fibrosis, although a few of these patients have already developed cirrhosis. Our study indicates that iron indices should be included in health check-ups, and if abnormal, should lead to further investigation.
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| 8. |
- Andersson, Anna, et al.
(författare)
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Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations
- 2005
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Ingår i: Leukemia. - : Springer Science and Business Media LLC. - 1476-5551 .- 0887-6924. ; 19:6, s. 1042-1050
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Tidskriftsartikel (refereegranskat)abstract
- Hematologic malignancies are characterized by fusion genes of biological/clinical importance. Immortalized cell lines with such aberrations are today widely used to model different aspects of leukemogenesis. Using cDNA microarrays, we determined the gene expression profiles of 40 cell lines as well as of primary leukemias harboring 11q23/MLL rearrangements, t(1;19)[TCF3/PBX1], t(12;21)[ETV6/RUNX1], t(8;21)[RUNX1/CBFA2T1], t(8;14) [IGH@/MYC], t(8;14)[TRA@/MYC], t(9;22)[BCR/ABL1], t(10;11) [PICALM/MLLT10], t(15;17)[PML/RARA], or inv(16)[CBFB/MYH11]. Unsupervised classification revealed that hematopoietic cell lines of diverse origin, but with the same primary genetic changes, segregated together, suggesting that pathogenetically important regulatory networks remain conserved despite numerous passages. Moreover, primary leukemias cosegregated with cell lines carrying identical genetic rearrangements, further supporting that critical regulatory pathways remain intact in hematopoietic cell lines. Transcriptional signatures correlating with clinical subtypes/primary genetic changes were identified and annotated based on their biological/molecular properties and chromosomal localization. Furthermore, the expression profile of tyrosine kinase-encoding genes was investigated, identifying several differentially expressed members, segregating with primary genetic changes, which may be targeted with tyrosine kinase inhibitors. The identified conserved signatures are likely to reflect regulatory networks of importance for the transforming abilities of the primary genetic changes and offer important pathogenetic insights as well as a number of targets for future rational drug design.
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- Andersson, Åke, et al.
(författare)
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Status of the new injector for MAX-lab
- 2002
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Ingår i: 8th European Particle Accelerator Conference. ; , s. 772-774
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Konferensbidrag (refereegranskat)abstract
- The new injector for MAX-lab is built around two 125 MeV linacs [B. Anderberg, (2000)] equipped with SLED cavities [Z.D. Farkas, (1974)]. The electron beam is recirculated once to reach 500 MeV. A 2.3 MeV thermionic RF gun [B. Anderberg, (2000)] injects into the system. The RF-gun is put into operation and commissioning of the first linac is proceeding. Results from the thermionic RF-gun operation, linac commissioning and first beam operations are presented.
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