| 1. |
- Lodén, M., et al.
(author)
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Sunscreen use : controversies, challenges and regulatory aspects
- 2011
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In: British Journal of Dermatology. - : Wiley-Blackwell Publishing Inc.. - 0007-0963 .- 1365-2133. ; 165:2, s. 255-262
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Journal article (peer-reviewed)abstract
- Mismatches between skin pigmentation and modern lifestyle continue to challenge our naked skin. One of our responses to these challenges is the development and use of sunscreens. The management of sunscreens has to balance their protective effect against erythema, photocarcinogenesis and photoageing owing to the potential toxicity of the ultraviolet (UV) filters for humans and the environment. The protection against UV radiation offered by sunscreens was recently standardized in the European Union (EU) based on international harmonization of measurement techniques. Four different categories of sun protection have been implemented along with recommendations on how to use sunscreen products in order to obtain the labelled protection. The UV filters in sunscreens have long been authorized for use by the EU authority on the basis of data from studies on acute toxicity, subchronic and chronic toxicity, reproductive toxicity, genotoxicity, photogenotoxicity, carcinogenicity, irritation, sensitization, phototoxicity and photosensitization as well as on environmental aspects. New challenges with respect to the safety of UV filters have arisen from the banning of animal experiments for the development of cosmetics. Future debates on sunscreens are likely to focus on nanoparticles and environmental issues, along with motivation campaigns to persuade consumers to protect their skin. However, more efficient sunscreen use will also continue to raise questions on the benefit in preventing vitamin D synthesis in the skin induced by sunlight.
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| 2. |
- Dahlqvist, J, et al.
(author)
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Multiple epiphyseal dysplasia
- 2009
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In: Acta orthopaedica. - : Medical Journals Sweden AB. - 1745-3682 .- 1745-3674. ; 80:6, s. 711-715
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Journal article (peer-reviewed)
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| 5. |
- Alahyari, H., et al.
(author)
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What Do Agile Teams Find Important for their Success?
- 2018
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In: 2018 25th Asia-Pacific Software Engineering Conference (APSEC). - : IEEE. - 9781728119700
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Conference paper (peer-reviewed)abstract
- Although the general benefits of agile methods have been shown, it is not always clear what makes the application of agile successful or not in a company. With this motivation, we investigate agile success factors, particularly from the viewpoint of teams. We conduct in-company surveys to collect and rank agile team success factors, comparing these results with success factors found in the literature. Our results introduce new success factors not previously discussed in related work. The findings emphasize the importance of team environment, team spirit, and team capability as opposed to previous work which emphasizes project management process and customer involvement. These findings can help find issues and improve the performance of agile teams.
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| 7. |
- Blomquist, H K, et al.
(author)
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Glycerol kinase deficiency in two brothers with and without clinical manifestations.
- 1996
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In: Clinical genetics. - 0009-9163 .- 1399-0004. ; 50:5, s. 375-9
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Journal article (peer-reviewed)abstract
- We report two brothers with glycerol kinase deficiency (GKD). The older brother had serious clinical symptoms, mental and growth retardation, abnormal skeleton, spontaneous fractures and premature loss of abnormal teeth. He and his mother had low serum phosphate levels. He had elevated serum and urine glycerol levels and GKD was found in cultured fibroblasts. Prenatal diagnosis was performed in the second pregnancy. Glycerol kinase activity was considered normal in a chorionic villus sample of the foetus. After birth, it was found that the boy had elevated serum and urine glycerol levels. Enzymatic analysis in cultured fibroblasts revealed that this boy also had GKD, in spite of having no expression of the disease. Chromosomal analyses in the parents and both boys were normal. Major rearrangements or deletions were not detected in molecular studies of DNA from the two brothers. The hybridisation pattern was normal and no allelic loss was observed.
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