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| 2. |
- Alehagen, Siw, 1953-, et al.
(författare)
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Catecholamine and cortisol reaction to childbirth
- 2001
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Ingår i: International Journal of Behavioral Medicine. - 1070-5503 .- 1532-7558. ; 8:1, s. 50-65
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Tidskriftsartikel (refereegranskat)abstract
- One way to study the stressfulness of childbirth is to examine the output of stress hormones. In this study, urinary catecholamines and salivary cortisol from 50 primiparous women were collected for 1 day during gestational weeks 37 to 39, hourly during labor and delivery, and 2 hr and 2 days postpartum. All three stress hormones increased statistically significantly from pregnancy to labor. The increase in adrenaline and cortisol was more than 500%, and the increase in noradrenaline was about 50%. After labor, the output decreased but not statistically significantly below the levels during late pregnancy. Hormone levels during late pregnancy, during labor and delivery, and during the period postpartum mostly did not correlate systematically. However, noradrenaline and adrenaline, as well as adrenaline and cortisol, were positively correlated during labor. After administration of epidural analgesia, there was a moderate but significant decrease in noradrenaline and adrenaline, whereas cortisol did not change. In conclusion, the results of this study support the assumption that childbirth is a very stressful event and that the stress responses vary considerably among women. The substantial increase of adrenaline and cortisol compared with noradrenaline indicates that mental stress is more dominant than physical stress during labor.
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| 3. |
- Busch, Hillevi, et al.
(författare)
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Self-efficacy beliefs predict sustained long-term sick absenteeism in individuals with chronic musculoskeletal pain
- 2007
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Ingår i: Pain Practice. - : Wiley. - 1530-7085 .- 1533-2500. ; 7:3, s. 234-240
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Tidskriftsartikel (refereegranskat)abstract
- Recovery beliefs are assumed to predict rehabilitation outcomes and return-to-work in various clinical conditions but are less frequently assessed in musculoskeletal disorders. We tested the hypothesis that recovery beliefs constitute a risk factor for sustained long-term sick absenteeism in men and women suffering from nonspecific chronic musculoskeletal disorders. A total of 233 subjects with a recent or ongoing experience of long-term sick leave were included in a prospective design. Subjects answered a postal baseline questionnaire and were followed up via register data for 1 year. Multivariate logistic regression analyses indicated that subjects with negative recovery beliefs (OR: 2.41; CI: 1.22–4.77), low sense of mastery (OR: 2.08; CI: 1.27–3.40), perceived high mental demands at work (OR: 1.77; CI: 1.05–2.99), and prior experiences of long-term sick absenteeism (OR: 1.86; CI: 1.02–3.37) had an increased probability of receiving sickness benefits at follow-up. We conclude that prolonged sickness absence contributes strongly to increase patients' sense of helplessness, lower self-efficacy, and hinder future work return. To improve work return, patients' maladaptive beliefs should be clarified and challenged early in the rehabilitation process.
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| 4. |
- Busch, Hillevi, et al.
(författare)
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Visuospatial and verbal memory in chronic pain patients: an explorative study.
- 2006
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Ingår i: Pain Practice. - : Wiley. - 1530-7085 .- 1533-2500. ; 6:3, s. 179-185
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Tidskriftsartikel (refereegranskat)abstract
- Cognitive bias, such as selective memory for pain-related information, is frequently observed in chronic pain patients and is assessed mostly using verbal material. Beside word lists, the current study used photographs of people presenting pain behaviours to assess memory bias in chronic pain patients. Chronic pain patients were hypothesized to show better recall of pain-related words and pictures as compared to pain-free controls. Twenty-eight female chronic neck patients and 28 pain-free female controls completed two computerized pictorial memory games and two word recall tasks. Patients and controls performed equally well in the neutral memory game. In the pain-related game, patients performed significantly worse than did controls. No significant differences were found in the word recall task. The result is discussed in terms of cognitive avoidance.
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| 5. |
- Busch, Hillevi, 1970-
(författare)
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When pain remains : Appraisals and adaptation
- 2007
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- As the number one cause of sick absenteeism and disability pension, musculoskeletal pain is considered a major health problem in Sweden and many other industrialized countries. Medical findings are often insufficient to explain the pain’s intensity or duration, and psychological factors are known to be important in understanding the aetiology and maintenance of pain. The current thesis examines the relationship between non-specific chronic musculoskeletal pain and cognitions, emotions and behaviours. In Study I, chronic pain patients were interviewed about pain experiences and the results indicated that some patients use psychological defences to deal with chronic pain. Study II was an experimental approach set up to study the association between chronic pain and selective memory. In a pictorial memory game, no differences were found between patients and controls in the neutral game. In the pain-related game patients decreased – and controls improved – their performance, a finding discussed in terms of cognitive avoidance. Study III used questionnaire and register data to examine the predictive value of psychosocial variables on sustained pain-related sick absenteeism and the results showed sense of mastery and recovery beliefs to be especially important. The studies are discussed in terms of emotional and defensive coping and it is suggested that defences can be related to excessive activity, which may increase the risk of future relapses. It was suggested that an increased acceptance of pain, at both an individual and a societal level – would favour rehabilitation and return-to-work for those suffering from persistent pain.
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| 6. |
- Chatziioannou, Aristotelis, et al.
(författare)
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Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases
- 2017
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 7
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Tidskriftsartikel (refereegranskat)abstract
- We recently reported that differential gene expression and DNA methylation profiles in blood leukocytes of apparently healthy smokers predicts with remarkable efficiency diseases and conditions known to be causally associated with smoking, suggesting that blood-based omic profiling of human populations may be useful for linking environmental exposures to potential health effects. Here we report on the sex-specific effects of tobacco smoking on transcriptomic and epigenetic features derived from genome-wide profiling in white blood cells, identifying 26 expression probes and 92 CpG sites, almost all of which are affected only in female smokers. Strikingly, these features relate to numerous genes with a key role in the pathogenesis of cardiovascular disease, especially thrombin signaling, including the thrombin receptors on platelets F2R (coagulation factor II (thrombin) receptor; PAR1) and GP5 (glycoprotein 5), as well as HMOX1 (haem oxygenase 1) and BCL2L1 (BCL2-like 1) which are involved in protection against oxidative stress and apoptosis, respectively. These results are in concordance with epidemiological evidence of higher female susceptibility to tobacco-induced cardiovascular disease and underline the potential of blood-based omic profiling in hazard and risk assessment.
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| 8. |
- Engelkes, Torbjörn, 1971-
(författare)
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Loyal until death (?) : The nature, measurement and predictors of loyalty in a military context
- 2024
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The overall aim of this thesis was to broaden the understanding of the concept of loyalty within a military context, by focusing on how the nature of loyalty is experienced, how it can be measured and how it can be predicted. To achieve this, the thesis was structured in three interrelated studies, which initially aimed to examine the content of loyalty within the Swedish Armed Forces (SAF), then to develop and validate a scale to measure loyalty, and finally to examine possible predictors of loyalty.The aim of Study I was to examine how loyalty is experienced within the SAF. To achieve this, Study I examined how high-ranking officers – presumed to have a large influence on professional ethics within the SAF – gave meaning to their experiences of loyalty. The results showed that although the nature of loyalty in the military organization is based on a strong identification with the profession, loyalty is a multifaceted phenomenon which requires the individual to manage competing and sometimes counteracting domains (objects) of loyalty.The aim of Study II was to develop a psychometric scale for measuring loyalty in a military context, based on the findings of Study I. Given the complex and varying nature of loyalty and dealing with different domains of loyalty in the military, the scale was developed to consider several domains for an individual’s loyalty (e.g., workgroup, mission, nation). Additionally, there was a focus on the overall nature of loyalty involving sacrifice and action to protect the domain of loyalty. To achieve this, three independent samples, consisting of military personnel (in training and on overseas mission), were invited to answer a questionnaire based on the results from Study I. Exploratory and confirmatory factor analyses resulted in a scale measuring loyalty, denoted the Swedish Military Loyalty Scale (SMiLS). The SMiLS was found to consist of a four-dimensional representation of the willingness to act loyally. The dimensions are sectioned in loyal sacrifice and loyal action, further divided into moderate and extreme loyal sacrifice and loyal action, respectively.The aim of Study III was to examine how individuals’ willingness to act loyally to certain domains (the closest workgroup, the unit, and the unit mission) can be predicted by social identity fusion and developmental leadership. To achieve this, a sample consisting of military personnel serving on an overseas mission in Mali, took part in a survey, using the SMiLS as the dependent variable. Demographic factors, such as rank and gender, were also examined, taking the outcome of loyalty into consideration. The results show that social identity mainly predicted the sacrificial dimensions of loyalty, while developmental leadership predicted all dimensions of loyalty for all domains.In conclusion, the present thesis broadens the understanding of loyalty within a military context. It also contributes with a scale for measuring loyalty and identifies two predictors for loyalty. Further research should focus on a deepened understanding of loyalty within the military and in the context of total defense organizations, further validation of the SMiLS and the examination of additional possible predictors for loyalty.
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| 9. |
- Falkenberg, Helena, 1977-
(författare)
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How privatization and corporatization affect healthcare employees’ work climate, work attitudes and ill-health : Implications of social status
- 2010
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Political liberalization and increased public costs have placed new demands on the Swedish public sector. Two ways of meeting these novel requirements have been to corporatize and privatize organizations. With these two organizational changes, however, comes a risk of increased insecurity and higher demands on employees; the ability to handle these changes is likely dependent on their social status within an organization. The general aim of the thesis is to contribute to the understanding of how corporatization and privatization might affect employees’ work climate, work attitudes and ill-health. Special importance is placed on whether outcomes may differ depending on the employees’ social status in the form of hierarchic level and gender. Questionnaire data from Swedish acute care hospitals were used in three empirical studies. Study I showed that physicians at corporatized and privatized hospitals reported more positive experiences of their work climate compared with physicians at a public administration hospital. Study II showed that privatization had more negative ramifications for a middle hierarchic level (i.e., registered nurses) who reported deterioration of work attitudes, while there were no major consequences for employees at high (physicians) or low (assistant nurses) hierarchic levels. Study III found that although the work situation for women and men physicians were somewhat comparable (i.e., the same occupation, the same organization), all of the differences that remained between the genders were to the detriment of women. The results of this thesis suggest that corporatizations and privatizations do not necessarily imply negative consequence for employees. However, the consequences appear to differ between groups with different social status. Employees whose immediate work situation is affected but who do not have sufficient resources to handle the requirements associated with an organizational change may perceive the most negative consequences.
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| 10. |
- Falkstedt, Daniel, 1973-, et al.
(författare)
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Psychosocial Functioning and Intelligence Both Partly Explain Socioeconomic Inequalities in Premature Death. A Population-Based Male Cohort Study
- 2013
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 8:12
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The possible contributions of psychosocial functioning and intelligence differences to socioeconomic status (SES)-related inequalities in premature death were investigated. None of the previous studies focusing on inequalities in mortality has included measures of both psychosocial functioning and intelligence. Methods: The study was based on a cohort of 49 321 men born 1949-1951 from the general community in Sweden. Data on psychosocial functioning and intelligence from military conscription at similar to 18 years of age were linked with register data on education, occupational class, and income at 35-39 years of age. Psychosocial functioning was rated by psychologists as a summary measure of differences in level of activity, power of initiative, independence, and emotional stability. Intelligence was measured through a multidimensional test. Causes of death between 40 and 57 years of age were followed in registers. Results: The estimated inequalities in all-cause mortality by education and occupational class were attenuated with 32% (95% confidence interval: 20-45%) and 41% (29-52%) after adjustments for individual psychological differences; both psychosocial functioning and intelligence contributed to account for the inequalities. The inequalities in cardiovascular and injury mortality were attenuated by as much as 51% (24-76%) and 52% (35-68%) after the same adjustments, and the inequalities in alcohol-related mortality were attenuated by up to 33% (8-59%). Less of the inequalities were accounted for when those were measured by level of income, with which intelligence had a weaker correlation. The small SES-related inequalities in cancer mortality were not attenuated by adjustment for intelligence. Conclusions: Differences in psychosocial functioning and intelligence might both contribute to the explanation of observed SES-related inequalities in premature death, but the magnitude of their contributions likely varies with measure of socioeconomic status and cause of death. Both psychosocial functioning and intelligence should be considered in future studies.
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