| 1. |
- Bahadoran, Zahra, et al.
(författare)
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Inorganic nitrate, a natural anti-obesity agent : A systematic review and meta-analysis of animal studies
- 2020
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Ingår i: EXCLI Journal. - 1611-2156. ; 19, s. 972-983
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Forskningsöversikt (refereegranskat)abstract
- Evidence for potential effects of inorganic nitrate (NO3) on body weight is limited to inconsistent findings of animal experiments. In this systematic review and meta-analysis, we aimed to quantify the overall effect of inorganic NO3, administered via drinking water, on body weight gain in rats. We searched PubMed, Scopus, and Embase databases, and the reference lists of published papers. Experiments on male rats, reported data on body weight in NO3-treated animals and controls, were included for quality assessment, meta-analyses, subgroup anal-yses, and meta-regressions. Of 173 initially obtained studies, 11 were eligible to be included in the analyses, which covered the years 2004 to 2019 and included a total of 43 intervention (n=395) and 43 control (n=395) arms. Overall, the final body weights were significantly lower in the NO3-supplemented groups compared to controls (WMD= –16.8 g, 95 % CI= –27.38, –6.24; P=0.002). Doses of NO3 higher than the median (> 72.94 mg L-1 d-1) and longer NO3 exposure (> 8 weeks) resulted in greater mean differences (WMD= –31.92 g, 95 % CI= –52.90, –10.94 and WMD= –23.16 g, 95 % CI= –35.64, –10.68 g). After exclusion of experiments using high doses of NO3 (> 400 mg L-1 d-1), the overall mean differences in body weights between the groups decreased by approxi-mately 37 % but remained statistically significant (WMD= –10.11 g, 95 % CI= –19.04, –1.19, P=0.026). Mean changes in body weight were affected by age, baseline values in body weight, and the duration of the studies. These preliminary experimental findings strongly support the hypothesis that NO3 can be considered as a natural anti-obesity agent.
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| 2. |
- Koochek, Afsaneh, et al.
(författare)
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Dietary differences between elderly Iranians living in Sweden and Iran a cross-sectional comparative study
- 2011
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Ingår i: BMC Public Health. - : Springer Science and Business Media LLC. - 1471-2458. ; 11, s. 411-
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Tidskriftsartikel (refereegranskat)abstract
- Background: During the last decades, global migration has increased and many immigrant groups have a higher prevalence than the native born population of several cardiovascular disease risk factors, including poor dietary habits. However, it is uncertain if dietary habits in immigrant populations reflect dietary habits in their country of origin or if the current diet is a consequence of the migration and possible change of dietary habits. The aim of this study was to examine possible dietary differences between elderly Iranians living in Stockholm, Sweden with elderly Iranians living in Tehran, Iran, taking into account sex, age, marital status, and education. Methods: Dietary intakes were assessed by semi - quantitative food frequency questionnaire in a cross-sectional study of 121 Iranians living in Stockholm and 52 Iranians living in Tehran, aged 60-80. Differences in dietary habits between the two groups was analysed by bootstrapped regression analyses with 1000 replications. Results: Iranians living in Sweden had significantly higher intake of protein, total fat, fiber than Iranians living in Iran, but lower consumption of carbohydrates. The observed differences in intake of macronutrients were reflected in consumed amount of all food items, which were higher among Iranians living in Iran with the exception of bread and grain consumption which was lower. Conclusions: There are general differences in dietary habits between Iranians living in Iran and Iranians living in Sweden. Parts of observed differences in dietary habits may reflect a favourable adoption process to the Swedish dietary habits after migration. Meanwhile other differences are point of concern in light of the high prevalence of overweight, among Iranians living in Sweden and can have unfavourable impact in particular in the context of cardiovascular health.
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| 3. |
- Koochek, Afsaneh, et al.
(författare)
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Is migration to Sweden associated with increased prevalence of risk factors for cardiovascular disease?
- 2008
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Ingår i: European Journal of Cardiovascular Prevention & Rehabilitation. - : Sage Publications. - 1741-8267 .- 1741-8275. ; 15:1, s. 78-82
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: [corrected] The proportion of elderly immigrants in Sweden is increasing. This is an important issue considering that the prevalence of cardiovascular disease (CVD) is a global health problem and that CVD is one of the main causes of morbidity among the elderly. The aim of this study is to analyze whether there is an association between migration status, that is being an elderly Iranian immigrant in Sweden, as compared with being an elderly Iranian in Iran, and the prevalence of risk factors for CVD. DESIGN: Population-based cross-sectional study with face-to-face interviews. PARTICIPANTS AND SETTING: A total of 176 Iranians in Stockholm and 300 Iranians in Tehran, aged 60-84 years. METHODS: The prevalence of general obesity, abdominal obesity, hypertension, smoking, and diabetes was determined. Unconditional logistic regression analysis was used to calculate odds ratios (ORs) with 95% confidence intervals (CIs) for outcomes. RESULTS: The age-adjusted risk of hypertension and smoking was higher in Iranian women and men in Sweden. OR for hypertension was 1.9 (95% CI: 1.1-3.2) for women and 3.1 (95% CI: 1.5-6.3) for men and OR for smoking was 6.9 (95% CI: 2.2-21.6) for women and 4.7 (95% CI: 2.0-11.0) for men. The higher risk for hypertension and smoking remained significant after accounting for age, socioeconomic status, and marital status. Abdominal obesity was found in nearly 80% of the women in both groups. CONCLUSION: The findings show a strong association between migration status and the prevalence of hypertension and smoking. Major recommendation for public health is increased awareness of CVD risk factors among elderly immigrants.
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| 4. |
- Ordookhani, Arash, et al.
(författare)
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Seasonal variation of neonatal transient hyperthyrotropinemia in tehran province, 1998–2005
- 2010
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Ingår i: Chronobiology International. - : Informa Healthcare. - 0742-0528 .- 1525-6073. ; 27:9-10, s. 1854-1869
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Tidskriftsartikel (refereegranskat)abstract
- Seasonal aggregation and the monthly rate of neonatal transient hyperthyrotropinemia(THT) were assessed. From November 1998 to April 2005, neonates of gestationalage ≥37 wks, birth weight 2500–4000 g, birth length 45–55 cm, and 1st min Apgarscore >3, who had thyrotropin (TSH) ≥20 mU/L in their cord dried-blood specimen,but without congenital hypothyroidism, were enrolled in the study. The recall rateequals the rate of THT occurrence in this study. Of 47,945 neonates, 555 had THT(recall rate: 1.2%). The aggregated seasonal recall rate (recall for further assessment torule out congenital hypothyroidism) was significantly higher in winter (January,February, and March) than the other seasons ( p < .0001). Winter had higher recallrate in each year as compared to other seasons, but the overall rate of recalls decreasedin 2001 and 2002. Excluding the first 6 months (due to erratic variations), the remaining72 months revealed a relatively sinusoidal pattern in monthly recall rates; indeed,there was an initial 11-month high recall rates (1.7%), followed by a 33-month decrease(0.7%), a 19-month increase (1.9%), and a final 9-month decrease (0.8%). The recallrate of each of these time intervals was significantly different from that of the nexttime interval ( p < .0001). The monthly recall rates were best fitted to cubic curve estimationand then autoregressive integrated moving average (ARIMA) (0, 1, 1) models.THT occurs significantly more in winter than in other seasons, and this suggests apossible role for time-varying factor(s) contributing to its seasonal preponderance.
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