| 1. |
- Mustafa, Mudassir Imran, et al.
(författare)
-
An Empirical Account of Fitness-Utility : A Case of Radical Change towards Mobility in DSR Practice
- 2014
-
Ingår i: Advancing the Impact of Design Science: Moving from Theory to Practice. - Cham : Springer International Publishing. - 9783319067001 - 3319067001 ; , s. 289-303
-
Bokkapitel (refereegranskat)abstract
- Evaluation is an essential part of design science research - a means to demonstrate qualities of artefacts and knowledge abstractions. The utilityfitness model suggests that evaluation needs to move from ‘usefulness’ measures to utility functions that incorporate the long-term evolution and survival of an artefact in its design landscape. In this paper, we interpret a process of innovative change taking place within a design system, in order to provide an empirical account of utility-fitness. We propose that the utility-fitness model pays too little explicit attention to technological-ecological fit, accountability, and robustness: Three ideals that were prevalent in the scrutinized empirical setting.
|
|
| 2. |
- Mustafa, Mudassir Imran, et al.
(författare)
-
Design Principles for Research Data Export : Lessons Learned in e-Health Design Research
- 2013
-
Ingår i: Design Science at the Intersection of Physical and Virtual Design. - Berlin, Heidelberg : Springer Berlin/Heidelberg. - 9783642388262 ; , s. 34-49
-
Konferensbidrag (refereegranskat)abstract
- Information technology (IT) allows for large-scale data collection and data analysis, e.g. through logs of user behavior and online surveys. While the issue of structured access to data is extremely important, previous research has not sufficiently emphasized design of data export for research purposes. If researchers are to make their data accessible, they must be empowered to export data in a flexible manner. In this paper, we employ action design research to develop design principles for data export in an e-Health context. Design is in- formed by a sociomaterial world-view, object-oriented patterns and principles, and usability goals. Through three build-intervene-evaluate cycles in an empiri- cal setting where randomized controlled trials are designed, we propose nine design principles and a conceptual architecture for data export. Implications for research and practice are discussed.
|
|
| 3. |
- Mustafa, Mudassir Imran, 1978-
(författare)
-
Sustaining the Usefulness of eHealth Research Software : Lessons Learned in Action Design Research
- 2019
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Research software is vital to advancement in the sciences, engineering, humanities, and all other fields. Scientific research is dependent on the quality of and accessibility to research software. Research software is often developed hastily to solve one-off problems, leading to flimsy code that is not sustainable or usable beyond the lifetime of a given research project and is difficult for researchers, outside of the original context, to use, reuse or extend. It is critical to address the many challenges related to the development, deployment, and maintenance of research software. Therefore, there is a growing concern in the scientific community regarding designing sustainable research software. The academic research context refers to the environment or community concerned with scientific research, sponsored by research grants and public funding. Despite the increasing dependence on research software, software development practices in academia lag far behind those in the commercial sector.Health care relies on a very complex information technology architecture with many different IT components and also has a highly complex governance structure alongside the very rapid technology development. Additionally, there are ever-increasing demands and needs from health care users for more flexibility, more functionality and making the care transparent and patient-centred. Taken together, this poses significant challenges for eHealth and Information Systems researchers, as each artefact, depending on the context, has different quality characteristics to operationalise the requirements under consideration.The research objective is to explore what Information Systems researchers and practitioners need to be aware of for sustaining the usefulness of eHealth research software, in the academic research context. This longitudinal action design research (ADR) project, with its three cases, was conducted in an eHealth research project over a period of six years. Contributions from this research include the identification of quality characteristics and their enactment in the actual organisational settings, as well as empirically grounded design principles and a typology for sustaining the usefulness of eHealth research software, based on a formalisation of learning in the three ADR cases. This dissertation also contributes to the method space with the introduction of the augmented action design research (AADR) method, an extension of ADR, on how to conduct multiple ADR projects that build towards an overarching knowledge aim.Practice contributions are the design and development of internet-based eHealth research software to offer patients psychological treatment and support for issues resulting from physical illnesses, while also providing a chance for researchers to study the effectiveness of the aid provided. The dissertation also contributed in a broader sense to the research software development practice, as the findings extend to research areas in which research software is needed to read and interpret research data, and where software must continue to function so that it allows continued access and use of research data.
|
|
| 4. |
- Zubair, Saima, et al.
(författare)
-
Complete genome sequence of Staphylococcus aureus, strain ILRI_Eymole1/1, isolated from a Kenyan dromedary camel
- 2015
-
Ingår i: Standards in Genomic Sciences. - : Springer Science and Business Media LLC. - 1944-3277. ; 10
-
Tidskriftsartikel (refereegranskat)abstract
- We report the genome of a Staphylococcus aureus strain (ILRI_Eymole1/1) isolated from a nasal swab of a dromedary camel (Camelus dromedarius) in North Kenya. The complete genome sequence of this strain consists of a circular chromosome of 2,874,302 bp with a GC-content of 32.88 %. In silico annotation predicted 2755 protein-encoding genes and 76 non-coding genes. This isolate belongs to MLST sequence type 30 (ST30). Phylogenetic analysis based on a subset of 283 core genes revealed that it falls within the human clonal complex 30 (CC30) S. aureus isolate cluster but is genetically distinct. About 79 % of the protein encoding genes are part of the CC30 core genome (genes common to all CC30 S. aureus isolates), similar to 18 % were within the variable genome (shared among multiple but not all isolates) and similar to 3 % were found only in the genome of the camel isolate. Among the 85 isolate-specific genes, 79 were located within putative phages and pathogenicity islands. Protein encoding genes associated with bacterial adhesion, and secretory proteins that are essential components of the type VII secretion system were also identified. The complete genome sequence of S. aureus strain ILRI_Eymole1/1 has been deposited in the European Nucleotide Archive under the accession no LN626917.1.
|
|
