| 1. |
- Fredriksson, Åsa, 1968, et al.
(author)
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Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigma S upon carbon starvation
- 2007
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In: Genes & Development. - : Cold Spring Harbor Laboratory. - 0890-9369 .- 1549-5477. ; 21:7, s. 862-874
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Journal article (peer-reviewed)abstract
- The {sigma}S subunit of RNA polymerase is a master regulator of Escherichia coli that retards cellular senescence and bestows cells with general stress protective functions during growth arrest. We show that mutations and drugs triggering translational errors elevate {sigma}S levels and stability. Furthermore, mutations enhancing translational fidelity attenuate induction of the rpoS regulon and prevent stabilization of {sigma}S upon carbon starvation. Destabilization of {sigma}S by increased proofreading requires the presence of the {sigma}S recognition factor SprE (RssB) and the ClpXP protease. The data further suggest that {sigma}S becomes stabilized upon starvation as a result of ClpP sequestration and this sequestration is enhanced by oxidative modifications of aberrant proteins produced by erroneous translation. ClpP overproduction counteracted starvation-induced stabilization of {sigma}S, whereas overproduction of a ClpXP substrate (ssrA-tagged GFP) stabilized {sigma}S in exponentially growing cells. We present a model for the sequence of events leading to the accumulation and activation of {sigma}S upon carbon starvation, which are linked to alterations in both ribosomal fidelity and efficiency.
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| 2. |
- Sieberer, Ulrich, et al.
(author)
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The Political Dynamics of Portfolio Design in European Democracies
- 2021
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In: British Journal of Political Science. - : Cambridge University Press. - 0007-1234 .- 1469-2112. ; 51:2, s. 772-787
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Journal article (peer-reviewed)abstract
- The design of government portfolios – that is, the distribution of competencies among government ministries and office holders – has been largely ignored in the study of executive and coalition politics. This article argues that portfolio design is a substantively and theoretically relevant phenomenon that has major implications for the study of institutional design and coalition politics. The authors use comparative data on portfolio design reforms in nine Western European countries since the 1970s to demonstrate how the design of government portfolios changes over time. Specifically, they show that portfolios are changed frequently (on average about once a year) and that such shifts are more likely after changes in the prime ministership or the party composition of the government. These findings suggest a political logic behind these reforms based on the preferences and power of political parties and politicians. They have major implications for the study of institutional design and coalition politics.
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| 3. |
- Albrecht, Frederike, et al.
(author)
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Patterns of Parliamentary Opposition : Empirical Evidence from the Deliberations in the German Bundestag’s Committee on European Union Affairs
- 2021
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In: Parliamentary Affairs. - : Oxford University Press. - 0031-2290 .- 1460-2482. ; 74:1, s. 230-251
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Journal article (peer-reviewed)abstract
- This article examines patterns of oppositional behaviour in the German Bundestag’s Committee on European Union Affairs (EAC) for two separate legislative periods (2005–2009 and 2009–2013). The study makes two contributions to previous research. It, first, shed some much-needed empirical light on political opposition in the Bundestag by examining how much and what kind of opposition exists in the German EAC. Secondly, the article examines the differences in oppositional behaviour of the Members of Parliament between the two legislative periods following an institutional reform in 2009 that afforded the Bundestag with increased opportunity structures in Europen Union affairs.
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| 4. |
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| 5. |
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| 6. |
- Bakardjieva Engelbrekt, Antonina, et al.
(author)
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The EU and Global Imbalances
- 2015
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In: The EU’s Role in Fighting Global Imbalances. - Cheltenham : Edward Elgar Publishing. - 9781784716721 - 9781784716738 - 978 1 78471 672 1 ; , s. 1-15
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Book chapter (peer-reviewed)
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| 7. |
- Bakardjieva Engelbrekt, Antonina, 1963-, et al.
(author)
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The EU’s Role in Fighting Global Imbalances
- 2015
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Book (peer-reviewed)abstract
- The EU’s Role in Fighting Global Imbalances looks at the role of the European Union in addressing some of the greatest challenges of our time: poverty, protectionism, climate change, and human trafficking. Contributions from ten leading scholars in the fields of economics, law, and political science provide in-depth analyses of three key dimensions of EU foreign policy, namely: the internal challenges facing the EU, as its 28 member countries struggle to coordinate their actions; the external challenges facing the EU on the global arena, in areas where global imbalances are particularly pervasive, and where measures taken by the Union can have an important impact; and the EU´s performance on the global arena, in the eyes of other key actors. Based on a broad and interdisciplinary understanding of the concept of global imbalances, this book argues that these challenges follow from pervasive global imbalances, which at root are economic, political, and legal in character.
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| 8. |
- Barow, Thomas, 1969, et al.
(author)
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Inclusive Education im Vereinigten Königreich und in Skandinavien
- 2022
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In: Handbuch Inklusion und Sonderpädagogik. - Bad Heilbrunn : Verlag Julius Klinkhardt. - 9783825288044 ; , s. 194-198
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Book chapter (peer-reviewed)abstract
- Ausgehend von der Etablierung des Inklusionsbegriffs in den 1990er Jahren beschreibt der Beitrag die national geprägten politischen und gesetzlichen Grundlagen inklusiver Bildung im Vereinigten Königreich und in Skandinavien. Die sonderpädagogischen Förderquoten werden dargelegt und ausgewählte Ergebnisse empirischer Forschung präsentiert. Die Verfasser problematisieren die uneinheitliche Definition von Inklusion und das Verhältnis von Inclusive Education zu Bildungs-systemen, die durch Marktorientierung und Wahlfreiheit charakterisiert sind. Hierbei kommt es zu paradoxalen Entwicklungen in Form einer Diagnose- bzw. Behandlungskultur und einer Renaissance gesonderter Unterrichtung. Diese widersprüchlichen Tendenzen bilden zugleich die zentralen Herausforderungen zukünftiger Schulentwicklung.
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| 9. |
- Barow, Thomas, 1969, et al.
(author)
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Inclusive Education in Großbritannien und Skandinavien
- 2015
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In: Handbuch Inklusion und Sonderpädagogik. - Bad Heilbrunn : Verlag Julius Klinkhardt. - 9783825286439 ; , s. 189-193
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Book chapter (peer-reviewed)abstract
- Ausgehend von der Etablierung des Inklusionsbegriffs in den 1990er Jahren beschreibt der Beitrag die national geprägten politischen und gesetzlichen Grundlagen inklusiver Bildung in Großbritannien und Skandinavien. Die sonderpädagogischen Förderquoten werden dargelegt und ausgewählte Ergebnisse empirischer Forschung präsentiert. Die Verfasser problematisieren die uneinheitliche Definition von Inklusion und das Verhältnis von Inclusive Education zu Bildungssystemen, die durch Marktorientierung und Wahlfreiheit charakterisiert sind. Hierbei kommt es zu paradoxalen Entwicklungen in Form einer Diagnose- bzw. Behandlungskultur und einer Renaissance gesonderter Unterrichtung. Diese widersprüchlichen Tendenzen bilden zugleich die zentralen Herausforderungen zukünftiger Schulentwicklung.
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| 10. |
- Bennich-Björkman, Li, 1960-, et al.
(author)
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Dags för Lemne att lämna
- 2015
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In: Upsala Nya Tidning. ; march 13
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Journal article (pop. science, debate, etc.)
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