| 1. |
- Catto, Peter J., et al.
(författare)
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A unified treatment of kinetic effects in a tokamak pedestal
- 2011
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 1361-6587 .- 0741-3335. ; 53, s. 054004-
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Tidskriftsartikel (refereegranskat)abstract
- We consider the effects of a finite pedestal radial electric field on ion orbits using a unified approach. We then employ these modified orbit results to retain finite E×B drift departures from flux surfaces in an improved drift-kinetic equation. The procedure allows us to make a clear distinction between transit averages and flux surface averages when solving this kinetic equation. The technique outlined here is intended to clarify and unify recent evaluations of the banana regime decrease and plateau regime alterations in the ion heat diffusivity; the reduction and possible reversal of the poloidal flow in the banana regime, and its augmentation in the plateau regime; the increase in the bootstrap current; and the enhancement of the residual zonal flow regulation of turbulence.
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| 2. |
- Catto, Peter J., et al.
(författare)
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Axisymmetric global gravitational equilibrium for magnetized, rotating hot plasma
- 2015
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Ingår i: Journal of Plasma Physics. - 0022-3778 .- 1469-7807. ; 81:06, s. 515810603-
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Tidskriftsartikel (refereegranskat)abstract
- We present analytic solutions for three-dimensional magnetized axisymmetric equilibria confining rotating hot plasma in a gravitational field. Our up–down symmetric solution to the full Grad–Shafranov equation can exhibit equatorial plane localization of the plasma density and current, resulting in disk equilibria for the plasma density. For very weak magnetic fields and high plasma pressure, we find strongly rotating thin plasma disk gravitational equilibria that satisfy strict Keplerian motion provided the gravitational energy is much larger than the plasma pressure, which must be large compared to the magnetic energy of the poloidal magnetic field. When the rotational energy exceeds the gravitational energy and it is larger than the plasma pressure, diffuse disk equilibrium solutions continue to exist provided the poloidal magnetic energy remains small. For stronger magnetic fields and lower plasma pressure and rotation, we can also find gravitational equilibria with strong localization to the equatorial plane. However, a toroidal magnetic field is almost always necessary to numerically verify these equilibria are valid solutions in the presence of gravity for the cases considered in Catto & Krasheninnikov (J. Plasma Phys., vol. 81, 2015, 105810301). In all cases both analytic and numerical results are presented.
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| 3. |
- Catto, Peter J., et al.
(författare)
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Electromagnetic zonal flow residual responses
- 2017
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Ingår i: Journal of Plasma Physics. - 0022-3778 .- 1469-7807. ; 83:3, s. Article no 905830402-
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Tidskriftsartikel (refereegranskat)abstract
- The collisionless axisymmetric zonal flow residual calculation for a tokamak plasma is generalized to include electromagnetic perturbations. We formulate and solve the complete initial value zonal flow problem by retaining the fully self-consistent axisymmetric spatial perturbations in the electric and magnetic fields. Simple expressions for the electrostatic, shear and compressional magnetic residual responses are derived that provide a fully electromagnetic test of the zonal flow residual in gyrokinetic codes. Unlike the electrostatic potential, the parallel vector potential and the parallel magnetic field perturbations need not relax to flux functions for all possible initial conditions.
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| 4. |
- Catto, Peter J., et al.
(författare)
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Three-dimensional magnetized and rotating hot plasma equilibrium and stability in a gravitational field
- 2015
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Ingår i: Europhysics Conference Abstracts. - 2914771983 ; 39E, s. O2.401-
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Konferensbidrag (refereegranskat)abstract
- We present analytic solutions for three-dimensional magnetized axisymmetric equilibria confining rotating hot plasma in a gravitational field. Our solution to the full Grad-Shafranov equation can exhibit strong equatorial plane localization of the plasma density and current, resulting in disk equilibria for the plasma density. Unlike in [P.J. Catto et al, 2015, J. Plasma Physics 81, 105810301], we find a toriodal magnetic field is necessary to find a equilibrium in the presence of gravity for most cases of interest. We expect our results to provide impetus to re-investigate magneto-rotational stability.
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| 5. |
- Catto, Peter J, et al.
(författare)
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Three-dimensional magnetized and rotating hot plasma equilibrium in a gravitational field
- 2015
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Ingår i: 57th Annual Meeting of the APS Division of Plasma Physics. ; 60:19, s. NP12.00113 -
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- We present analytic and numerical solutions for three-dimensional magnetized axisymmetric equilibria confining rotating hot plasma in a gravitational field. Our solution to the full Shafranov-Grad equation can exhibit strong equatorial plane localization of the plasma density and current, resulting in disk equilibria for the plasma density. We find that a toriodal magnetic field is sometimes necessary to find a equilibrium in the presence of gravity for many cases of interest.
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| 6. |
- Gulyas, Katalin, et al.
(författare)
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Effects of 1-year anti-TNF-α therapies on bone mineral density and bone biomarkers in rheumatoid arthritis and ankylosing spondylitis
- 2020
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Ingår i: Clinical Rheumatology. - : Springer Science and Business Media LLC. - 0770-3198 .- 1434-9949. ; 39:1, s. 167-175
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Tidskriftsartikel (refereegranskat)abstract
- ObjectivesRheumatoid arthritis (RA) and ankylosing spondylitis (AS) have been associated with generalized and localized bone loss. We conducted a comprehensive study using imaging (dual-energy X-ray absorptiometry, DXA) and laboratory biomarkers in order to determine bone health and to study the effects of anti-tumor necrosis factor (TNF) biologics in RA and AS.Patients and methodsThirty-six RA and 17 AS patients undergoing 1-year etanercept (ETN) or certolizumab-pegol (CZP) therapy were studied. Bone density was assessed by DXA at baseline and after 12 months. Serum C-reactive protein (CRP), calcium, phosphate, parathyroid hormone (PTH), vitamin D3, osteocalcin, procollagen type I N-propeptide (P1NP), C-terminal telopeptide (βCTX), osteoprotegerin, sclerostin (SOST), Dickkopf-1 (DKK-1), soluble receptor activator nuclear kappa B ligand (sRANKL), and cathepsin K (cathK) levels were determined at baseline and after 6 and 12 months.ResultsTNF-α inhibition was clinically effective. Anti-TNF-α halted further bone loss over 1 year. In general, anti-TNF therapy significantly increased P1NP, SOST levels, and the P1NP/βCTX ratios, while decreased DKK-1 and CathK production at different time points in most patient subsets. In the full cohort and in RA, baseline and/or 12-month bone mineral density (BMD) at multiple sites exerted inverse relationships with CRP and βCTX, and positive correlation with SOST. In AS, L2-4 BMD after 1-year biologic therapy inversely correlated with baseline βCTX, while femoral neck BMD rather showed inverse correlations with CRP.ConclusionsAnti-TNF therapy slowed down generalized bone loss, in association with clinical improvements, in both diseases. TNF blockade may enhance bone formation and suppress joint destruction. Anti-TNF therapy may act inversely on DKK-1 and SOST. Independent predictors of BMD were SOST and βCTX in RA, whilst CRP in AS.
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| 7. |
- Pusztai, Istvan, 1983, et al.
(författare)
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Neoclassical Plateau Regime Transport in a Tokamak Pedestal
- 2010
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Ingår i: Europhysics Conference Abstracts. - 2914771622 ; 34A, s. P1.1082-
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- In subsonic tokamak pedestals the radial scale of plasma profiles can be comparable to the ion poloidal Larmor radius thereby making the radial electrostatic field so strong that the E×B drift has to be retained in the ion kinetic equation in the same order as the parallel streaming when B_pol
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| 8. |
- Pusztai, Istvan, 1983, et al.
(författare)
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Neoclassical plateau regime transport in a tokamak pedestal
- 2010
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 1361-6587 .- 0741-3335. ; 52:7, s. 075016-
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Tidskriftsartikel (refereegranskat)abstract
- In tokamak pedestals with subsonic flows the radial scale of plasma profiles can be comparable to the ion poloidal Larmor radius, thereby making the radial electrostatic field so strong that the E × B drift has to be retained in the ion kinetic equation in the same order as the parallel streaming. The modifications of neoclassical plateau regime transport—such as the ion heat flux and the poloidal ion and impurity flows—are evaluated in the presence of a strong radial electric field. The altered poloidal ion flow can lead to a significant increase in the bootstrap current in the pedestal where the spatial profile variation is strong because of the enhanced coefficient of the ion temperature gradient term near the electric field minimum. Unlike the banana regime, orbit squeezing does not affect the plateau regime results.
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| 9. |
- Pusztai, Lajos, et al.
(författare)
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De Novo Oligometastatic Breast Cancer
- 2023
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Ingår i: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. - 1527-7755. ; 41:34, s. 5237-5241
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 10. |
- Varga, Gábor, et al.
(författare)
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Cu(II)-amino acid–CaAl-layered double hydroxide complexes, recyclable, efficient catalysts in various oxidative transformations
- 2016
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Ingår i: Journal of Molecular Catalysis A: Chemical. - : Elsevier BV. - 1381-1169. ; 423, s. 49-60
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Tidskriftsartikel (refereegranskat)abstract
- Intercalated composite materials were prepared with CaAl-layered double hydroxide as host and Cu(II)-amino acid (L-cysteine, L-histidine and L-tyrosine) complex anions as guests. Two methods (intercalation of the ligand first followed by constructing the complex; preforming the complex first, then introducing it among the layers of the host) and optimization of the synthesis conditions were performed to obtain composites having the complex exclusively among the layers. The composite materials were structurally characterized by powder X-ray diffractometry, mid infrared (IR) spectroscopy with ATR (attenuated total reflectance) or photoacoustic detections, transmission and scanning electron microscopies and X-ray photoelectron spectroscopy. Structural features of the intercalant (coordination number, coordination sites) were elucidated by classical chemical and energy dispersive X-ray analyses, EPR (electron paramagnetic spectroscopy), X-ray absorption and far IR spectroscopies. Structural models based on these methods are also given. Catalytic activities, selectivities and recycling abilities of the substances were studied in the oxidation reactions of cyclohexene with peracetic acid and in situ formed iodosylbenzene as oxidants in the liquid phase. The catalysts were active in the Ullmann coupling reaction as well. The intercalated substances were found to be efficient and highly selective catalysts with very good recycling abilities.
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