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Träfflista för sökning "WFRF:(Roca C) "

Search: WFRF:(Roca C)

  • Result 1-10 of 98
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  • 2021
  • swepub:Mat__t
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  • 2021
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  • de Rojas, I., et al. (author)
  • Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
  • 2021
  • In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1
  • Journal article (peer-reviewed)abstract
    • Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer’s disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer’s disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer’s disease. © 2021, The Author(s).
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  • Ageron, M., et al. (author)
  • ANTARES : The first undersea neutrino telescope
  • 2011
  • In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier. - 0168-9002 .- 1872-9576. ; 656:1, s. 11-38
  • Journal article (peer-reviewed)abstract
    • The ANTARES Neutrino Telescope was completed in May 2008 and is the first operational Neutrino Telescope in the Mediterranean Sea. The main purpose of the detector is to perform neutrino astronomy and the apparatus also offers facilities for marine and Earth sciences. This paper describes the design, the construction and the installation of the telescope in the deep sea, offshore from Toulon in France. An illustration of the detector performance is given. (C) 2011 Elsevier B.V. All rights reserved.
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  • Result 1-10 of 98
Type of publication
journal article (89)
conference paper (4)
research review (2)
book chapter (1)
Type of content
peer-reviewed (88)
other academic/artistic (8)
Author/Editor
Roca, J (31)
Rodriguez-Martinez, ... (15)
Costantini, H. (10)
Junker, M. (9)
Imbriani, G. (9)
Straniero, O. (9)
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Vomiero, Alberto (9)
Romano, M. (8)
Naumann-Godo, M. (8)
Rostovtsev, A. (7)
Kooijman, P. (7)
Aguilar, J. A. (7)
Kappes, A. (7)
Karg, T. (7)
Montaruli, T. (7)
Anton, G. (7)
Katz, U. (7)
Brunner, J. (7)
Albert, A. (7)
Cuneo, S. (7)
Becherini, Yvonne (7)
Carr, J. (7)
Zaborov, D. (7)
Vallage, B. (7)
Feinstein, F. (7)
Carmona, E. (7)
Giacomelli, G. (7)
Margiotta, A. (7)
Popa, V. (7)
Spurio, M. (7)
Olivetto, C. (7)
de, Botton N (7)
van, Dantzig R (7)
Anghinolfi, M. (7)
Anvar, S. (7)
Aubert, J-J. (7)
Basa, S. (7)
Bertin, V. (7)
Bouwhuis, M. C. (7)
Circella, M. (7)
Coyle, P. (7)
Deschamps, A. (7)
Hallewell, G. (7)
Hello, Y. (7)
Hernandez-Rey, J. J. (7)
de Jong, M. (7)
Kouchner, A. (7)
Lo Presti, D. (7)
Loucatos, S. (7)
Louis, F. (7)
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University
Karolinska Institutet (44)
Linköping University (20)
Lund University (20)
Uppsala University (13)
University of Gothenburg (9)
Luleå University of Technology (9)
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Linnaeus University (7)
Stockholm University (6)
Royal Institute of Technology (5)
Swedish University of Agricultural Sciences (4)
Mid Sweden University (3)
Chalmers University of Technology (3)
Högskolan Dalarna (3)
Umeå University (2)
Jönköping University (1)
Marie Cederschiöld högskola (1)
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Language
English (98)
Research subject (UKÄ/SCB)
Natural sciences (31)
Medical and Health Sciences (28)
Engineering and Technology (4)
Agricultural Sciences (3)
Social Sciences (1)

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