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1.	Sahlin, K, et al. (author) Phosphocreatine content in single fibers of human muscle after sustained submaximal exercise 1997 In: The American journal of physiology. - 0002-9513. ; 273:11 Pt 1, s. C172-C178 Journal article (peer-reviewed)
2.	Ahmed, O, et al. (author) Ezetimibe in Combination With Simvastatin Reduces Remnant Cholesterol Without Affecting Biliary Lipid Concentrations in Gallstone Patients 2018 In: Journal of the American Heart Association. - 2047-9980. ; 7:24, s. e009876- Journal article (peer-reviewed)
3.	Crona, Mikael, et al. (author) NrdH-Redoxin Protein Mediates High Enzyme Activity in Manganese-reconstituted Ribonucleotide Reductase from Bacillus anthracis 2011 In: Journal of Biological Chemistry. - Bethesda, Md. : American Society for Biochemistry and Molecular Biology. - 0021-9258 .- 1083-351X. ; 286:38, s. 33053-33060 Journal article (peer-reviewed)abstract Bacillus anthracis is a severe mammalian pathogen encoding a class Ib ribonucleotide reductase (RNR). RNR is a universal enzyme that provides the four essential deoxyribonucleotides needed for DNA replication and repair. Almost all Bacillus spp. encode both class Ib and class III RNR operons, but the B. anthracis class III operon was reported to encode a pseudogene, and conceivably class Ib RNR is necessary for spore germination and proliferation of B. anthracis upon infection. The class Ib RNR operon in B. anthracis encodes genes for the catalytic NrdE protein, the tyrosyl radical metalloprotein NrdF, and the flavodoxin protein NrdI. The tyrosyl radical in NrdF is stabilized by an adjacent Mn(2)(III) site (Mn-NrdF) formed by the action of the NrdI protein or by a Fe(2)(III) site (Fe-NrdF) formed spontaneously from Fe(2+) and O(2). In this study, we show that the properties of B. anthracis Mn-NrdF and Fe-NrdF are in general similar for interaction with NrdE and NrdI. Intriguingly, the enzyme activity of Mn-NrdF was approximately an order of magnitude higher than that of Fe-NrdF in the presence of the class Ib-specific physiological reductant NrdH, strongly suggesting that the Mn-NrdF form is important in the life cycle of B. anthracis. Whether the Fe-NrdF form only exists in vitro or whether the NrdF protein in B. anthracis is a true cambialistic enzyme that can work with either manganese or iron remains to be established.
4.	Fernstrom, M., et al. (author) Skeletal muscle mitochondrial function and ROS production in response to extreme endurance exercise in athletes 2006 In: Biochimica et Biophysica Acta - Bioenergetics. - 0005-2728 .- 1879-2650. ; , s. 413-414 Journal article (other academic/artistic)
5.	Hojlund, K, et al. (author) Mitochondrial dysfunction in type 2 diabetes and obesity 2008 In: Endocrinology and metabolism clinics of North America. - : Elsevier BV. - 0889-8529. ; 37:3, s. 713- Journal article (peer-reviewed)
6.	Lindstrand, A, et al. (author) Integration of genome sequencing into health care - experiences from 3211 rare disease patients show high diagnostic rates across multiple clinical entities 2020 In: EUROPEAN JOURNAL OF HUMAN GENETICS. - : SPRINGERNATURE. - 1018-4813 .- 1476-5438. ; 28:SUPPL 1, s. 52-53 Conference paper (other academic/artistic)
7.	Littmann, K, et al. (author) SIMVASTATIN AND EZETIMIBE REDUCE PLASMA LIPOPROTEIN BINDING TO HUMAN ARTERIAL PROTEOGLYCANS IN GALLSTONE DISEASED PATIENTS 2018 In: ATHEROSCLEROSIS. - : Elsevier BV. - 0021-9150. ; 275, s. E234-E234 Conference paper (other academic/artistic)
8.	Mogensen, M, et al. (author) Mitochondrial respiratory function is decreased in skeletal muscles of patients with type 2 diabetes 2006 In: DIABETOLOGIA. - 0012-186X. ; 49, s. 121-122 Conference paper (other academic/artistic)
9.	Persson, Marta, 1979, et al. (author) Comprehensive molecular characterization of adenoid cystic carcinoma reveals tumor suppressors as novel drivers and prognostic biomarkers 2023 In: Journal of Pathology. - 0022-3417. ; 261:3, s. 256-268 Journal article (peer-reviewed)abstract Adenoid cystic carcinoma (ACC) is a MYB-driven head and neck malignancy with high rates of local recurrence and distant metastasis and poor long-term survival. New effective targeted therapies and clinically useful biomarkers for patient stratification are needed to improve ACC patient survival. Here, we present an integrated copy number and transcriptomic analysis of ACC to identify novel driver genes and prognostic biomarkers. A total of 598 ACCs were studied. Clinical follow-up was available from 366 patients, the largest cohort analyzed to date. Copy number losses of 1p36 (70/492; 14%) and of the tumor suppressor gene PARK2 (6q26) (85/343; 25%) were prognostic biomarkers; patients with concurrent losses (n = 20) had significantly shorter overall survival (OS) than those with one or no deletions (p < 0.0001). Deletion of 1p36 independently predicted short OS in multivariate analysis (p = 0.02). Two pro-apoptotic genes, TP73 and KIF1B, were identified as putative 1p36 tumor suppressor genes whose reduced expression was associated with poor survival and increased resistance to apoptosis. PARK2 expression was markedly reduced in tumors with 6q deletions, and PARK2 knockdown increased spherogenesis and decreased apoptosis, indicating that PARK2 is a tumor suppressor in ACC. Moreover, analysis of the global gene expression pattern in 30 ACCs revealed a transcriptomic signature associated with short OS, multiple copy number alterations including 1p36 deletions, and reduced expression of TP73. Taken together, the results indicate that TP73 and PARK2 are novel putative tumor suppressor genes and potential prognostic biomarkers in ACC. Our studies provide new important insights into the pathogenesis of ACC. The results have important implications for biomarker-driven stratification of patients in clinical trials.
10.	Sahlin, K, et al. (author) Energy supply and muscle fatigue in humans 1998 In: Acta physiologica Scandinavica. - 0001-6772. ; 162:3, s. 261-266 Journal article (peer-reviewed)

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Result 1-10 of 88

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Type of publication: journal article (69); conference paper (15); book (2); reports (1); book chapter (1)

Type of content: peer-reviewed (66); other academic/artistic (21); pop. science, debate, etc. (1)

Author/Editor: Sahlin, L (10); Sahlin, S (9); Marko-Varga, György (9); Malm, Johan (8); Sahlin, K. Barbara (8); Appelqvist, Roger (8); show more...; Sanchez, Aniel (8); Sahlin, Kent (7); Nordenskjold, M (5); Walsh, B. (4); Giwercman, Aleksande ... (4); Gustafsson, U (4); Nilsson, D (4); Lieden, A (4); Gustavsson, P (4); Ahmed, O (3); Eriksson, M (3); Nordgren, A (3); Pettersson, M. (3); Pramfalk, C (3); Parini, P (3); Soder, O (3); Lindstrand, A (3); Kvarnung, M (3); Bakkman, Linda (3); Wang, H. (2); Larsson, L (2); Sandelin, K (2); Pettersson, K (2); Grigelioniene, G (2); Wedell, A (2); Stenman, Göran, 1953 (2); Wiklund, Ingela (2); Littmann, K (2); Oorni, K (2); Camejo, G (2); Bjorck, E (2); Hallberg, A (2); Papadogiannakis, N (2); Wirta, Valtteri (2); Skoog, L (2); Ygberg, S (2); Pampanini, V (2); Malmgren, H (2); Olofsson, K (2); Jahnukainen, K (2); Larhed, M (2); Wincent, J (2); Andersen, Claus Ydin ... (2); Tham, E. (2); show less...

University: Karolinska Institutet (63); Lund University (10); Högskolan Dalarna (10); Uppsala University (8); The Swedish School of Sport and Health Sciences (6); Royal Institute of Technology (4); show more...; Umeå University (3); Stockholm University (3); Mid Sweden University (3); University of Gothenburg (2); The Nordic Africa Institute (1); Luleå University of Technology (1); Linnaeus University (1); Swedish University of Agricultural Sciences (1); IVL Swedish Environmental Research Institute (1); show less...

Language: English (86); Swedish (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (24); Natural sciences (7); Social Sciences (3)

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