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Träfflista för sökning "WFRF:(Sancisi V) "

Search: WFRF:(Sancisi V)

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  • Sweed, N, et al. (author)
  • Liver X receptor β regulates bile volume and the expression of aquaporins and cystic fibrosis transmembrane conductance regulator in the gallbladder
  • 2021
  • In: American journal of physiology. Gastrointestinal and liver physiology. - : American Physiological Society. - 1522-1547 .- 0193-1857. ; 321:34, s. G243-G251
  • Journal article (peer-reviewed)abstract
    • This report reveals a novel and specific role of the nuclear receptor liver X receptor β (LXRβ) in controlling biliary tree pathophysiology. LXRβ−/− mice have high gallbladder bile volume and are affected by a cholangiopathy that resembles cystic fibrosis. We found LXRβ to regulate the expression of both aquaporins water channels and the cystic fibrosis transmembrane conductance regulator. This opens a new field in biliary tree pathophysiology, enlightening a possible transcription factor controlling CFTR expression.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Kim, HJ (1)
Hultenby, K (1)
Parini, P (1)
Strandvik, B (1)
Gabbi, C (1)
Barros, R. (1)
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Sweed, N (1)
Sancisi, V (1)
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University
Karolinska Institutet (1)
Language
English (1)
Year
2021 (1)

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