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- Tanash, H, et al.
(författare)
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The risk of burn injury during long term oxygen therapy : a 17-year longitudinal national study in Sweden
- 2015
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Ingår i: Annals of Burns and Fire Disasters. - 1592-9566. ; 28
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Tidskriftsartikel (refereegranskat)abstract
- Background: Long-term oxygen therapy (LTOT) improves the survival time in chronic obstructivepulmonary disease (COPD) complicated by severe hypoxemia. Despite warnings about potentialdangers, a considerable number of patients continue to smoke whilst on LTOT. The incidence ofburn injuries related to LTOT is not known. The aim of this study was to estimate the rate of burninjury that required contact with health care during LTOT.Methods: a prospective, population-based, consecutive cohort study of people starting LTOT fromany cause between 1 January 1992 and 31 December 2009 in the Swedish national Register ofRespiratory Failure (Swedevox).Results: Between 1992 and 2009, 12,497 patients (53% women) started LTOT and were includedin the study. The mean (SD) age was 72 ± 9 years. The main reasons for starting LTOT were COPD(75%) and pulmonary fibrosis (15%). Only 269 (2%) were active smokers at starting LTOT. Themedian follow-up time to event was 1.5 (P25 to P75, 0.55 to 3.1) years. In total, 17 patients had adiagnosed burn injury during LTOT in 27890 person-years of follow-up. The rate of burn injuryduring LTOT was 61(95% CI, 36-98) per 100.000 person-years. Of the 17 burn injuries, five wereinhalation injuries and 12 skin injuries (3 third degree burns and one second degree; six (50%) werefacial burns). Two deaths were related to burn injury during LTOT. There was no significantdifference in the rate of burn injury between ever-smokers and never-smokers neither between menand women.Conclusion: the rate of burn injuries in patients with LTOT seems to be low in Sweden. This couldbe attributable to Swedish strict requirements on smoking cessation before LTOT initiation
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| 2. |
- Torén, Kjell, 1952, et al.
(författare)
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Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study
- 2020
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Ingår i: Bmj Open Respiratory Research. - : BMJ. - 2052-4439. ; 7:1
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Tidskriftsartikel (refereegranskat)abstract
- Background The diagnosis of chronic obstructive pulmonary disease is based on the presence of persistent respiratory symptoms and chronic airflow limitation (CAL). CAL is based on the ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1:FVC) after bronchodilation, and FEV1:FVC less than the fifth percentile is often used as a cut-off for CAL. The aim was to investigate if increasing percentiles of FEV1:FVC were associated withany respiratory symptom(cough with phlegm, dyspnoea or wheezing) in a general population sample of never-smokers and ever-smokers. Methods In a cross-sectional study comprising 15 128 adults (50-64 years), 7120 never-smokers and 8008 ever-smokers completed a respiratory questionnaire and performed FEV(1)and FVC after bronchodilation. We calculated theirz-scores for FEV1:FVC and defined the fifth percentile using the Global Lung Function Initiative (GLI) reference value, GLI(5)and increasing percentiles up to GLI(25). We analysed the associations between different strata of percentiles and prevalence ofany respiratory symptomusing multivariable logistic regression for estimation of OR. Results Among all subjects, regardless of smoking habits, the odds ofany respiratory symptomwere elevated up to the GLI(15-20)strata. Among never-smokers, the odds ofany respiratory symptomwere elevated at GLI(<5)(OR 3.57, 95% CI 2.43 to 5.23) and at GLI(5-10)(OR 2.57, 95% CI 1.69 to 3.91), but not at higher percentiles. Among ever-smokers, the odds ofany respiratory symptomwere elevated from GLI(<5)(OR 4.64, 95% CI 3.79 to 5.68) up to GLI(>= 25)(OR 1.33, 95% CI 1.00 to 1.75). Conclusions The association between percentages of FEV1:FVC and respiratory symptoms differed depending on smoking history. Our results support a higher percentile cut-off for FEV1:FVC for never-smokers and, in particular, for ever-smokers.
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