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- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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- Chatterjee, Saion, et al.
(författare)
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Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia
- 2016
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Ingår i: Diabetes Care. - : American Diabetes Association. - 0149-5992 .- 1935-5548. ; 39:2, s. 300-307
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE Type 2 diabetes confers a greater excess risk of cardiovascular disease in women than in men. Diabetes is also a risk factor for dementia, but whether the association is similar in women and men remains unknown. We performed a meta-analysis of unpublished data to estimate the sex-specific relationship between women and men with diabetes with incident dementia. RESEARCH DESIGN AND METHODS A systematic search identified studies published prior to November 2014 that had reported on the prospective association between diabetes and dementia. Study authors contributed unpublished sex-specific relative risks (RRs) and 95% CIs on the association between diabetes and all dementia and its subtypes. Sex-specific RRs and the women-to-men ratio of RRs (RRRs) were pooled using random-effects meta-analyses. RESULTS Study-level data from 14 studies, 2,310,330 individuals, and 102,174 dementia case patients were included. In multiple-adjusted analyses, diabetes was associated with a 60% increased risk of any dementia in both sexes (women: pooled RR 1.62 [95% CI 1.45–1.80]; men: pooled RR 1.58 [95% CI 1.38–1.81]). The diabetes-associated RRs for vascular dementia were 2.34 (95% CI 1.86–2.94) in women and 1.73 (95% CI 1.61–1.85) in men, and for nonvascular dementia the RRs were 1.53 (95% CI 1.35–1.73) in women and 1.49 (95% CI 1.31–1.69) in men. Overall, women with diabetes had a 19% greater risk for the development of vascular dementia than men (multiple-adjusted RRR 1.19 [95% CI 1.08–1.30]; P < 0.001). CONCLUSIONS Individuals with type 2 diabetes are at ∼60% greater risk for the development of dementia compared with those without diabetes. For vascular dementia, but not for nonvascular dementia, the additional risk is greater in women.
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- Conte, Gianpaolo, 1974-
(författare)
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Vision-Based Localization and Guidance for Unmanned Aerial Vehicles
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The thesis has been developed as part of the requirements for a PhD degree at the Artificial Intelligence and Integrated Computer System division (AIICS) in the Department of Computer and Information Sciences at Linköping University.The work focuses on issues related to Unmanned Aerial Vehicle (UAV) navigation, in particular in the areas of guidance and vision-based autonomous flight in situations of short and long term GPS outage.The thesis is divided into two parts. The first part presents a helicopter simulator and a path following control mode developed and implemented on an experimental helicopter platform. The second part presents an approach to the problem of vision-based state estimation for autonomous aerial platforms which makes use of geo-referenced images for localization purposes. The problem of vision-based landing is also addressed with emphasis on fusion between inertial sensors and video camera using an artificial landing pad as reference pattern. In the last chapter, a solution to a vision-based ground object geo-location problem using a fixed-wing micro aerial vehicle platform is presented.The helicopter guidance and vision-based navigation methods developed in the thesis have been implemented and tested in real flight-tests using a Yamaha Rmax helicopter. Extensive experimental flight-test results are presented.
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