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Sökning: WFRF:(Wegener Martin)

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1.
  • Marto, João Pedro, et al. (författare)
  • Safety and Outcome of Revascularization Treatment in Patients With Acute Ischemic Stroke and COVID-19: The Global COVID-19 Stroke Registry.
  • 2023
  • Ingår i: Neurology. - 1526-632X. ; 100:7
  • Tidskriftsartikel (refereegranskat)abstract
    • COVID-19-related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.This was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 and June 2021 tested for severe acute respiratory syndrome coronavirus 2 infection. With a doubly robust model combining propensity score weighting and multivariate regression, we studied the association of COVID-19 with intracranial bleeding complications and clinical outcomes. Subgroup analyses were performed according to treatment groups (IVT-only and EVT).Of a total of 15,128 included patients from 105 centers, 853 (5.6%) were diagnosed with COVID-19; of those, 5,848 (38.7%) patients received IVT-only and 9,280 (61.3%) EVT (with or without IVT). Patients with COVID-19 had a higher rate of symptomatic intracerebral hemorrhage (SICH) (adjusted OR 1.53; 95% CI 1.16-2.01), symptomatic subarachnoid hemorrhage (SSAH) (OR 1.80; 95% CI 1.20-2.69), SICH and/or SSAH combined (OR 1.56; 95% CI 1.23-1.99), 24-hour mortality (OR 2.47; 95% CI 1.58-3.86), and 3-month mortality (OR 1.88; 95% CI 1.52-2.33). Patients with COVID-19 also had an unfavorable shift in the distribution of the modified Rankin score at 3 months (OR 1.42; 95% CI 1.26-1.60).Patients with AIS and COVID-19 showed higher rates of intracranial bleeding complications and worse clinical outcomes after revascularization treatments than contemporaneous non-COVID-19 patients receiving treatment. Current available data do not allow direct conclusions to be drawn on the effectiveness of revascularization treatments in patients with COVID-19 or to establish different treatment recommendations in this subgroup of patients with ischemic stroke. Our findings can be taken into consideration for treatment decisions, patient monitoring, and establishing prognosis.The study was registered under ClinicalTrials.gov identifier NCT04895462.
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2.
  • Aaron, F. D., et al. (författare)
  • Combined measurement and QCD analysis of the inclusive e(+/-)p scattering cross sections at HERA
  • 2010
  • Ingår i: Journal of High Energy Physics. - 1029-8479. ; :1
  • Tidskriftsartikel (refereegranskat)abstract
    • A combination is presented of the inclusive deep inelastic cross sections measured by the H1 and ZEUS Collaborations in neutral and charged current unpolarised e(+/-)p scattering at HERA during the period 1994-2000. The data span six orders of magnitude in negative four-momentum-transfer squared, Q(2), and in Bjorken x. The combination method used takes the correlations of systematic uncertainties into account, resulting in an improved accuracy. The combined data are the sole input in a NLO QCD analysis which determines a new set of parton distributions, HERAPDF1.0, with small experimental uncertainties. This set includes an estimate of the model and parametrisation uncertainties of the fit result.
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3.
  • Aaron, F. D., et al. (författare)
  • Events with an isolated lepton and missing transverse momentum and measurement of W production at HERA
  • 2010
  • Ingår i: Journal of High Energy Physics. - 1029-8479. ; 2010:3, s. 1-19
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for events containing an isolated electron or muon and missing trans verse momentum produced in e(+/-)p collisions is performed with the H1 and ZEUS detectors at HERA. The data were taken in the period 1994-2007 and correspond to an integrated luminosity of 0.98 fb(-1). The observed event yields are in good overall agreement with the Standard Model prediction, which is dominated by single W production. In the e(+)p data, at large hadronic transverse momentum P-T(X) > 25GeV, a total of 23 events are observed compared to a prediction of 14.0 +/- 1.9. The total single W boson production cross section is measured as 1.06 +/- 0.16 (stat.) +/- 0.07 (sys.) pb, in agreement with an Standard Model (SM) expectation of 1.26 +/- 0.19 pb.
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4.
  • Aaron, F. D., et al. (författare)
  • Multi-leptons with high transverse momentum at HERA
  • 2009
  • Ingår i: Journal of High Energy Physics. - : Springer Science and Business Media LLC. - 1029-8479. ; :10
  • Tidskriftsartikel (refereegranskat)abstract
    • Events with at least two high transverse momentum leptons (electrons or muons) are studied using the H1 and ZEUS detectors at HERA with an integrated luminosity of 0.94 fb(-1). The observed numbers of events are in general agreement with the Standard Model predictions. Seven di- and tri-lepton events are observed in e(+)p collision data with a scalar sum of the lepton transverse momenta above 100 GeV while 1.94 +/- 0.17 events are expected. Such events are not observed in e(-)p collisions for which 1.19 +/- 0.12 are predicted. Total visible and differential di-electron and di-muon photoproduction cross sections are extracted in a restricted phase space dominated by photon-photon collisions.
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5.
  • McCall, Martin, et al. (författare)
  • Roadmap on transformation optics
  • 2018
  • Ingår i: Journal of Optics. - : IOP Publishing. - 2040-8978 .- 2040-8986. ; 20:6
  • Forskningsöversikt (refereegranskat)abstract
    • Transformation optics asks, using Maxwell's equations, what kind of electromagnetic medium recreates some smooth deformation of space? The guiding principle is Einstein's principle of covariance: that any physical theory must take the same form in any coordinate system. This requirement fixes very precisely the required electromagnetic medium. The impact of this insight cannot be overestimated. Many practitioners were used to thinking that only a few analytic solutions to Maxwell's equations existed, such as the monochromatic plane wave in a homogeneous, isotropic medium. At a stroke, transformation optics increases that landscape from 'few' to 'infinity', and to each of the infinitude of analytic solutions dreamt up by the researcher, there corresponds an electromagnetic medium capable of reproducing that solution precisely. The most striking example is the electromagnetic cloak, thought to be an unreachable dream of science fiction writers, but realised in the laboratory a few months after the papers proposing the possibility were published. But the practical challenges are considerable, requiring meta-media that are at once electrically and magnetically inhomogeneous and anisotropic. How far have we come since the first demonstrations over a decade ago? And what does the future hold? If the wizardry of perfect macroscopic optical invisibility still eludes us in practice, then what compromises still enable us to create interesting, useful, devices? While three-dimensional (3D) cloaking remains a significant technical challenge, much progress has been made in two dimensions. Carpet cloaking, wherein an object is hidden under a surface that appears optically flat, relaxes the constraints of extreme electromagnetic parameters. Surface wave cloaking guides sub-wavelength surface waves, making uneven surfaces appear flat. Two dimensions is also the setting in which conformal and complex coordinate transformations are realisable, and the possibilities in this restricted domain do not appear to have been exhausted yet. Beyond cloaking, the enhanced electromagnetic landscape provided by transformation optics has shown how fully analytic solutions can be found to a number of physical scenarios such as plasmonic systems used in electron energy loss spectroscopy and cathodoluminescence. Are there further fields to be enriched? A new twist to transformation optics was the extension to the spacetime domain. By applying transformations to spacetime, rather than just space, it was shown that events rather than objects could be hidden from view; transformation optics had provided a means of effectively redacting events from history. The hype quickly settled into serious nonlinear optical experiments that demonstrated the soundness of the idea, and it is now possible to consider the practical implications, particularly in optical signal processing, of having an 'interrupt-without-interrupt' facility that the so-called temporal cloak provides. Inevitable issues of dispersion in actual systems have only begun to be addressed. Now that time is included in the programme of transformation optics, it is natural to ask what role ideas from general relativity can play in shaping the future of transformation optics. Indeed, one of the earliest papers on transformation optics was provocatively titled 'General Relativity in Electrical Engineering'. The answer that curvature does not enter directly into transformation optics merely encourages us to speculate on the role of transformation optics in defining laboratory analogues. Quite why Maxwell's theory defines a 'perfect' transformation theory, while other areas of physics such as acoustics are not apparently quite so amenable, is a deep question whose precise, mathematical answer will help inform us of the extent to which similar ideas can be extended to other fields. The contributors to this Roadmap, who are all renowned practitioners or inventors of transformation optics, will give their perspectives into the field's status and future development.
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6.
  • Wegener, Moritz, 1990-, et al. (författare)
  • Techno-economic optimization model for polygeneration hybridenergy storage systems using biogas and batteries
  • 2021
  • Ingår i: Energy. - : Elsevier BV. - 0360-5442 .- 1873-6785. ; 218, s. 119544-
  • Tidskriftsartikel (refereegranskat)abstract
    • Renewable energy polygeneration systems are a viable alternative to fossil-fuel based systems, but storage solutions may be necessary when aiming for high sustainability and autonomy. As each storage technology has different strengths and weaknesses, combinations of various storage solutions may lead to better techno-economic performance than singular approaches. To this purpose, an optimization model including a novel dispatch control strategy for a hybrid energy storage system (HESS) is proposed, which uses biogas for long-term and batteries for short-term storage. The model optimizes for minimum lifetime costs while exploiting the biomass resources with maximum efficiency and quantifying the additional solar and battery capacities needed. It is applied in a case study with an innovative biomass-based polygeneration system in a rural locality of Bolivia to serve electricity, potable water, and bio-slurry as fertilizer. The results indicate that even with maximized efficiency of the biomass resource conversion, large PV and battery capacities are necessary to satisfy the electricity demand of the locality. Despite of the high investment costs, the biomass-based polygeneration system would cost 22% less over the project lifetime than the fossil-fuel based reference system while being less dependent on fuel price changes. It would also reduce CO2-emissions by over 98%.
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7.
  • Aaron, F. D., et al. (författare)
  • Combined inclusive diffractive cross sections measured with forward proton spectrometers in deep inelastic ep scattering at HERA
  • 2012
  • Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 72:10
  • Tidskriftsartikel (refereegranskat)abstract
    • A combination of the inclusive diffractive cross section measurements made by the H1 and ZEUS Collaborations at HERA is presented. The analysis uses samples of diffractive deep inelastic ep scattering data at a centre-of-mass energy root s = 318 GeV where leading protons are detected by dedicated spectrometers. Correlations of systematic uncertainties are taken into account, resulting in an improved precision of the cross section measurement which reaches 6 % for the most precise points. The combined data cover the range 2.5 < Q(2) < 200 GeV2 in photon virtuality, 0.00035 < x(P) < 0.09 in proton fractional momentum loss, 0.09 < vertical bar t vertical bar < 0.55 GeV2 in squared four-momentum transfer at the proton vertex and 0.0018 < beta < 0.816 in beta = x/x(P), where x is the Bjorken scaling variable.
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8.
  • Aaron, F. D., et al. (författare)
  • Deeply virtual Compton scattering and its beam charge asymmetry in e(+/-)p collisions at HERA
  • 2009
  • Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 681:5, s. 391-399
  • Tidskriftsartikel (refereegranskat)abstract
    • A measurement of elastic deeply virtual Compton scattering gamma*p --> gamma p using e(+) p and e(-) p collision data recorded with the HI detector at HERA is presented. The analysed data sample corresponds to an integrated luminosity of 306 pb(-1), almost equally shared between both beam charges. The cross section is measured as a function of the virtuality Q(2) of the exchanged photon and the centre-of-mass energy W of the gamma*p system in the kinematic domain 6.5 < Q(2) < 80 GeV2, 30 < W < 140 GeV and |t| < 1 GeV2, where t denotes the squared momentum transfer at the proton vertex. The cross section is determined differentially in t for different Q(2) and W values and exponential t-slope parameters are derived. Using e(+) p and e(-) p data samples, a beam charge asymmetry is extracted for the first time in the low Biorken x kinematic domain. The observed asymmetry is attributed to the interference between Bethe-Heitler and deeply virtual Compton scattering processes. Experimental results are discussed in the context of two different models, one based on generalised parton distributions and one based on the dipole approach. (C) 2009 Elsevier B.V. All rights reserved.
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9.
  • Aaron, F. D., et al. (författare)
  • Diffractive electroproduction of rho and phi mesons at HERA
  • 2010
  • Ingår i: Journal of High Energy Physics. - 1029-8479. ; 2010:5, s. 1-111
  • Tidskriftsartikel (refereegranskat)abstract
    • Diffractive electroproduction of rho and phi mesons is measured at HERA with the H1 detector in the elastic and proton dissociative channels. The data correspond to an integrated luminosity of 51 pb(-1). About 10500 rho and 2000 phi events are analysed in the kinematic range of squared photon virtuality 2.5 <= Q(2) <= 60 GeV2, photon-proton centre of mass energy 35 <= W <= 180 GeV and squared four-momentum transfer to the proton vertical bar t vertical bar <= 3 GeV2. The total, longitudinal and transverse cross sections are measured as a function of Q(2), W and vertical bar t vertical bar. The measurements show a transition to a dominantly "hard" behaviour, typical of high gluon densities and small q (q) over bar dipoles, for Q(2) larger than 10 to 20 GeV2. They support flavour independence of the diffractive exchange, expressed in terms of the scaling variable (Q(2) + M-V(2))/4, and proton vertex factorisation. The spin density matrix elements are measured as a function of kinematic variables. The ratio of the longitudinal to transverse cross sections, the ratio of the helicity amplitudes and their relative phases are extracted. Several of these measurements have not been performed before and bring new information on the dynamics of diffraction in a QCD framework. The measurements are discussed in the context of models using generalised parton distributions or universal dipole cross sections.
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10.
  • Aaron, F. D., et al. (författare)
  • Measurement of the charm and beauty structure functions using the H1 vertex detector at HERA
  • 2010
  • Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 65:1-2, s. 89-109
  • Tidskriftsartikel (refereegranskat)abstract
    • Inclusive charm and beauty cross sections are measured in e (-) p and e (+) p neutral current collisions at HERA in the kinematic region of photon virtuality 5a parts per thousand currency signQ (2)a parts per thousand currency sign2000 GeV2 and Bjorken scaling variable 0.0002a parts per thousand currency signxa parts per thousand currency sign0.05. The data were collected with the H1 detector in the years 2006 and 2007 corresponding to an integrated luminosity of 189 pb(-1). The numbers of charm and beauty events are determined using variables reconstructed by the H1 vertex detector including the impact parameter of tracks to the primary vertex and the position of the secondary vertex. The measurements are combined with previous data and compared to QCD predictions.
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  • Resultat 1-10 av 59

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