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- CARLSTEN, S, et al.
(author)
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RADAR TECHNIQUES FOR INDICATING INTERNAL EROSION IN EMBANKMENT DAMS
- 1995
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In: JOURNAL OF APPLIED GEOPHYSICS. - : ELSEVIER SCIENCE BV. - 0926-9851. ; 33:1-3, s. 143-156
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Journal article (other academic/artistic)abstract
- For improved dam safety in Sweden, radar techniques have been tested for detecting anomalous zones in the central core of embankment dams and the level of the core crest. Anomalies in the core may indicate a continuing process and a greater risk of intern
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- Mill, O., et al.
(author)
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Analysis and development of hydro power research : synthesis within Swedish Hydro Power Centre
- 2010
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Reports (other academic/artistic)abstract
- The market for hydropower re-investments in Sweden is approx 2.5 billion SEK/yr the coming decade. Large investments will also be carried out in Swedish tailing dams. This will result in challenging projects and need of experts. A crucial factor for a successful management of these challenges is the supply of engineers and researchers with hydro power and dam skills and knowledge. Swedish Hydro Power Centre (Svenskt vattenkraftcentrum, SVC) is a competence centre for university education and research environments within hydro power and mining dams. SVC comprises of two knowledge areas: Hydraulic Engineering and Hydro Turbines and Generators, respectively. SVC builds high-quality and long term sustainable knowledge at selected universities...
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- Nishio, Akiyosho, et al.
(author)
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Comparative studies of mitochondrial autoantibodies in sera and bile in primary biliary cirrhosis
- 1997
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In: Hepatology. - : Ovid Technologies (Wolters Kluwer Health). - 0270-9139 .- 1527-3350. ; 25:5, s. 1085-1089
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Journal article (peer-reviewed)abstract
- Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by destruction of intrahepatic bile ducts. Although the pathogenesis of this disease is still unknown, high titers of antimitochondrial autoantibodies (AMA) have long been recognized in patient sera. However, little is known about the presence of AMA in bile. In this study, we investigated bile and sera from patients with PBC and healthy controls for the presence of AMA and mitochondrial autoantigens. AMA were detected in the bile of 17 of 19 patients (89.4%) with PBC; they were specifically directed against the pyruvate dehydrogenase complex (PDC-E2) in 15 of 19 patients (78.9%), to the branched-chain 2-oxo-acid dehydrogenase complex E2 (BCOADC-E2) in 6 of 19 patients (31.6%), and to the 2-oxoglutarate dehydrogenase complex E2 (OGDC-E2) in 1 of 19 patients (5.3%). In a comparative study of sera from the same patients, anti-PDC-E2 antibodies were found in 19 of 19 patients (100%), anti-BCOADC in 9 of 19 patients (47.3%), and anti-OGDC-E2 in 4 of 19 patients (21.1%) patients. AMA in bile were always found together with antibodies of corresponding specificities in the serum from the same patient. Immunoglobulin (Ig)A AMA were found in the bile of 9 of 19 patients (47.7%) with PBC; they were specifically directed against PDC-E2 in 8 of 19 patients (42.1%) and to BCOADC in 2 of 19 patients (10.5%). Epitope mapping of IgA anti-PDC-E2 antibodies indicated that, like serum autoantibodies, the immunodominant epitope is directed against the inner lipoyl domain of PDC-E2. The prevalence and antigen reactivity of IgA AMA in sera correlated completely with IgA AMA in bile. Autoantibodies against nuclear envelope pore proteins (gp210) were found in 1 of 8 (12.5%) sera of patients with PBC, but not in bile. Furthermore, and of particular interest, we detected the autoantigens, PDC-E2, OGDC-E2, and BCOADC-E2, in the bile of 12 of 19 patients (63.2%), 9 of 19 patients (47.4%), and 9 of 19 patients (47.4%), respectively; PDC-E2 was found in only 1 of 17 (5.9%) disease controls. Although the presence of AMA in bile may merely reflect the presence of these antibodies in sera, the simultaneous detection of mitochondrial autoantigens in bile suggests an increase of mitochondrial autoantigens at inflammatory sites. Such autoantigens, coupled with AMA, may augment the local immune response and disease progression.
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- WORMAN, A
(author)
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COUPLED HYDROLOGICAL AND BIOGEOCHEMICAL MODEL FOR AQUEOUS CONTAMINANT TRANSPORT
- 1995
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In: MARINE AND FRESHWATER RESEARCH. - : C S I R O PUBLICATIONS. - 1323-1650. ; 46:1, s. 197-208
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Journal article (other academic/artistic)abstract
- A coupled hydrological and biogeochemical model for aqueous contaminant transport has been developed on the basis of field data on phosphorus transport in minor drainage brooks through agricultural areas in Sweden. Large scattering exists in constitutive
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- Worman, A, et al.
(author)
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Stochastic analysis of internal erosion in soil structures - Implications for risk assessments
- 2001
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In: JOURNAL OF HYDRAULIC ENGINEERING-ASCE. - : ASCE-AMER SOC CIVIL ENGINEERS. - 0733-9429. ; 127:5, s. 419-428
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Journal article (peer-reviewed)abstract
- A new modeling framework for internal erosion in heterogeneous stratified soils is developed by combining existing methods used to study sediment transport in canals, filtration phenomena, and stochastic processes. The framework is used to study the erosi
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- WORMAN, A, et al.
(author)
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SYSTEM HETEROGENEITY AS VARIABLE FOR SOLUTE TRANSPORT IN STREAMS
- 1995
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In: JOURNAL OF HYDRAULIC ENGINEERING-ASCE. - : ASCE-AMER SOC CIVIL ENG. - 0733-9429. ; 121:11, s. 782-791
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Journal article (other academic/artistic)abstract
- Contaminant migration in streaming waters is characterized by a large number of physical and biochemical transfer mechanisms that often exhibit marked spatial and temporal variabilities. To quantify the mass transport and particularly the mass retention i
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