| 1. |
- Wang, Yan, et al.
(författare)
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The Formation of a Dry-Belt in the North Side of Central Himalaya Mountains
- 2019
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Ingår i: Geophysical Research Letters. - 0094-8276 .- 1944-8007. ; 46, s. 2993-3000
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Tidskriftsartikel (refereegranskat)abstract
- ©2019. American Geophysical Union. All Rights Reserved. South Asian monsoon crosses the Himalayan Mountains (HMs) and brings moisture for precipitations in the South Tibetan Plateau. A distinct dry-belt was found in the north of the central HM region, where there are the highest and steepest mountains in the world. Through in situ and remote-sensing observations and convection-permitting numerical experiments, the current study demonstrates that the formation of the dry-belt is mainly due to the depletion of water vapor when the monsoonal flow climbs the steep south slope of the HMs. The foehn phenomenon is notable over the north slope of the HMs, but the hot and dry downslope flow does not significantly reduce the amount of the precipitation; instead, it can delay the peak of the diurnal precipitation in the north side of the HMs.
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| 2. |
- Zheng, Fenglian, et al.
(författare)
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Structural and functional hippocampal alterations in Multiple sclerosis and neuromyelitis optica spectrum disorder
- 2022
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Ingår i: Multiple Sclerosis Journal. - : SAGE Publications. - 1352-4585 .- 1477-0970. ; 28:5, s. 707-717
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Tidskriftsartikel (refereegranskat)abstract
- Background: Hippocampal involvement may differ between multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Objective: To investigate the morphometric, diffusion and functional alterations in hippocampus in MS and NMOSD and the clinical significance. Methods: A total of 752 participants including 236 MS, 236 NMOSD and 280 healthy controls (HC) were included in this retrospective multi-center study. The hippocampus and subfield volumes, fractional anisotropy (FA) and mean diffusivity (MD), amplitude of low frequency fluctuation (ALFF) and degree centrality (DC) were analyzed, and their associations with clinical variables were investigated. Results: The hippocampus showed significantly lower volume, FA and greater MD in MS compared to NMOSD and HC (p < 0.05), while no abnormal ALFF or DC was identified in any group. Hippocampal subfields were affected in both diseases, though subiculum, presubiculum and fimbria showed significantly lower volume only in MS (p < 0.05). Significant correlations between diffusion alterations, several subfield volumes and clinical variables were observed in both diseases, especially in MS (R = -0.444 to 0.498, p < 0.05). FA and MD showed fair discriminative power between MS and HC, NMOSD and HC (AUC > 0.7). Conclusions: Hippocampal atrophy and diffusion abnormalities were identified in MS and NMOSD, partly explaining how clinical disability and cognitive impairment are differentially affected.
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