| 1. |
- Engert, Andreas, et al.
(författare)
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The European Hematology Association Roadmap for European Hematology Research : a consensus document
- 2016
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Ingår i: Haematologica. - Pavia, Italy : Ferrata Storti Foundation (Haematologica). - 0390-6078 .- 1592-8721. ; 101:2, s. 115-208
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Tidskriftsartikel (refereegranskat)abstract
- The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at (sic)23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.
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| 2. |
- Buckland, Philip I., Dr. 1973-, et al.
(författare)
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The intricate details of using research databases and repositories for environmental archaeology data
- 2022
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Ingår i: ArcheoLogica Data. - Sesto Fiorentino : All’Insegna del Giglio. - 2785-0307. ; 2, s. 15-29
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Tidskriftsartikel (refereegranskat)abstract
- Environmental archaeology is a complex mix of empirical analysis and qualitative interpretation.It is increasingly data science oriented, and databases and online resources are becoming increasinglyimportant in large scale synthesis research on changes in climate, environments and human activities.Research funders, journals and universities place much emphasis on the use of data repositories toensure transparency and reusability in the research process. Although these are important, researchersthemselves, however, may have more use for research databases which are oriented more towardsadvanced querying and exploratory data analysis than conforming to archiving standards. This paperexplores the pros and cons of these different approaches. It also discusses and problematizes somekey concepts in research data management, including the definitions of data and metadata, along withthe FAIR principles. Research examples are provided from a broad field of environmental archaeologyand palaeoecology. In contrast to most publications, the developer’s perspective is also included, anda worked example using the Strategic Environmental Archaeology Database (SEAD) to investigate fossilbeetle data demonstrates the implementation of some of this in the real world. This example may befollowed online using the SEAD browser, and all described data downloaded from there. After providingboth encouragement and warnings on the use of digital resources for synthesis research, some suggestionsare made for moving forward.
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| 3. |
- Edvardsson, Johannes, et al.
(författare)
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Old wood in a new light : an online dendrochronological database
- 2023
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Ingår i: International Journal of Wood Culture. - : Brill Academic Publishers. - 2772-3194 .- 2772-3186. ; 3:1-3, s. 442-463
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Tidskriftsartikel (refereegranskat)abstract
- The Old Wood in a New Light database project focuses on the digitization and accessibility of the results of dendrochronological samples analyzed and archived at four Swedish university-based tree-ring laboratories at Lund University, Stockholm University, University of Gothenburg, and the Swedish University of Agricultural Sciences. Collaboration with the Environmental Archaeology Laboratory and Humlab at Umeå University enables long-term open access to data, raw data, and metadata. In this project, we (1) systematically undertake large-scale entry and open access publication of results from wood samples scientifically analyzed and archived by Swedish laboratories and the associated metadata, into the Strategic Environmental Archaeology Database (SEAD; www.sead.se) research data infrastructure, and (2) actively promote the database as a resource for new and ongoing interdisciplinary research initiatives. Including dendrochronological data in SEAD infrastructure allows interdisciplinary studies that combine major scientific and societal questions. Building on a pilot study of construction timber from southern Sweden and adaptation of SEAD digitization workflows, more than 70 000 samples archived at the four dendrochronological laboratories are now being handled in the project. The broad coverage of research networks, stakeholder interaction, and strategic support from the cultural heritage community is guaranteed owing to the ongoing collaboration between laboratories and an established international and multidisciplinary reference group.
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